Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Shu-pei Wang"'
Autor:
Hao Yang, Francis Rossignol, Denis Cyr, Rachel Laframboise, Shu Pei Wang, Jean-François Soucy, Marie-Thérèse Berthier, Yves Giguère, Paula J. Waters, Grant A. Mitchell
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 14, Iss C, Pp 55-58 (2018)
Background: A high level of succinylacetone (SA) in blood is a sensitive, specific marker for the screening and diagnosis of hepatorenal tyrosinemia (HT1, MIM 276700). HT1 is caused by mutations in the FAH gene, resulting in deficiency of fumarylacet
Externí odkaz:
https://doaj.org/article/95486fd6a0e04bf1be78ba0866a34b6f
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007110 (2017)
Fatty liver is a major health problem worldwide. People with hereditary deficiency of hormone-sensitive lipase (HSL) are reported to develop fatty liver. In this study, systemic and tissue-specific HSL-deficient mice were used as models to explore th
Externí odkaz:
https://doaj.org/article/8f3a35c0d0c8486db29bb8f3701d7399
Autor:
Jiang Wei Wu, Christoph Preuss, Shu Pei Wang, Hao Yang, Bo Ji, Gregory W Carter, Rebecca Gladdy, Gregor Andelfinger, Grant A Mitchell
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006716 (2017)
Liposarcoma is an often fatal cancer of fat cells. Mechanisms of liposarcoma development are incompletely understood. The cleavage of fatty acids from acylglycerols (lipolysis) has been implicated in cancer. We generated mice with adipose tissue defi
Externí odkaz:
https://doaj.org/article/a0b0eaee1f8e4f3f930f8e286f846a77
Autor:
Xiao Zhang, Cong Cong Zhang, Hao Yang, Krishnakant G. Soni, Shu Pei Wang, Grant A. Mitchell, Jiang Wei Wu
Publikováno v:
Cells, Vol 8, Iss 5, p 395 (2019)
White adipose tissue (WAT) lipolysis contributes to energy balance during fasting. Lipolysis can proceed by the sequential hydrolysis of triglycerides (TGs) by adipose triglyceride lipase (ATGL), then of diacylglycerols (DGs) by hormone-sensitive lip
Externí odkaz:
https://doaj.org/article/2d07d1b227d74bdf8ad6869688d7ffd3
Autor:
Mélanie Fortier, Krishnakant Soni, Nancy Laurin, Shu Pei Wang, Pascale Mauriège, Frank R. Jirik, Grant A. Mitchell
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 9, Pp 1860-1867 (2005)
In white adipose tissue (WAT), hormone-sensitive lipase (HSL) can mediate lipolysis, a central pathway in obesity and diabetes. Gene-targeted HSL-deficient (HSL−/−) mice with no detectable HSL peptide or activity (measured as cholesteryl esterase
Externí odkaz:
https://doaj.org/article/5cd97dd477104490869973c80ae1584e
Publikováno v:
International Journal of Technology and Human Interaction. 15:47-62
Chinese word segmentation is the basis of the Chinese natural language processing (NLP). With the development of the deep learning, various neural network models are applied to the Chinese word segmentation. However, current neural network models hav
Publikováno v:
Biochemical Society Transactions. 47:149-155
Coenzyme A (CoA) thioesters (acyl-CoAs) are essential intermediates of metabolism. Inborn errors of acyl-CoA metabolism include a large fraction of the classical organic acidemias. These conditions can involve liver, muscle, heart and brain, and can
Autor:
Nicolas Gauthier, Jiang Wei Wu, Shu Pei Wang, Pierre Allard, Orval A Mamer, Lawrence Sweetman, Ann B Moser, Lisa Kratz, Fernando Alvarez, Yves Robitaille, François Lépine, Grant A Mitchell
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e60581 (2013)
Most conditions detected by expanded newborn screening result from deficiency of one of the enzymes that degrade acyl-coenzyme A (CoA) esters in mitochondria. The role of acyl-CoAs in the pathophysiology of these disorders is poorly understood, in pa
Externí odkaz:
https://doaj.org/article/4d0f5c0fde574a7592e72437d2ea3c54
Autor:
Marie-Thérèse Berthier, Yves Giguère, Paula J. Waters, Rachel Laframboise, Jean-François Soucy, Denis Cyr, Grant A. Mitchell, Hao Yang, Francis Rossignol, Shu Pei Wang
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 14, Iss C, Pp 55-58 (2018)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports
Background A high level of succinylacetone (SA) in blood is a sensitive, specific marker for the screening and diagnosis of hepatorenal tyrosinemia (HT1, MIM 276700 ). HT1 is caused by mutations in the FAH gene, resulting in deficiency of fumarylacet
Autor:
Jiang Wei Wu, Cong Cong Zhang, Shu Pei Wang, Xiao Zhang, Grant A. Mitchell, Krishnakant G. Soni, Hao Yang
Publikováno v:
Cells, Vol 8, Iss 5, p 395 (2019)
Cells
Volume 8
Issue 5
Cells
Volume 8
Issue 5
White adipose tissue (WAT) lipolysis contributes to energy balance during fasting. Lipolysis can proceed by the sequential hydrolysis of triglycerides (TGs) by adipose triglyceride lipase (ATGL), then of diacylglycerols (DGs) by hormone-sensitive lip