Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shu-mei Xu"'
Autor:
Lai-xiang Lin, Xiang-yu Bo, Yuan-zhen Tan, Feng-xian Sun, Ming Song, Juan Zhao, Zhi-hong Ma, Mei Li, Kai-jun Zheng, Shu-Mei Xu
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112052 (2014)
β-amyloid hypothesis is the predominant hypothesis in the study of pathogenesis of Alzheimer's disease. This hypothesis claims that aggregation and neurotoxic effects of amyloid β (Aβ) is the common pathway in a variety of etiological factors for
Externí odkaz:
https://doaj.org/article/aa850f24086e44958dfada5b77bd7931
Publikováno v:
Applied Microbiology and Biotechnology. 102:2225-2234
Clethramycin (1) and mediomycin A (2) belong to the linear polyene polyketide (LPP) family of antibiotics that exhibit potent antifungal activity. Structural similarities exist between 1 and 2, except that 2 contains an amino moiety substituted for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fec4df3129875b05e3516a0a04fff34
https://doi.org/10.1007/s00253-017-8729-z
https://doi.org/10.1007/s00253-017-8729-z
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 35(1)
To study the effect of β-sheet blocking peptide H102 on the expression of AMPK-mTOR autophagy pathway-related protein in APP/PS1 double transgenic AD mice.Thirty male APP/PS1 transgenic male AD mice of 6 months old were randomly divided into AD grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f77c29bb19febad42a61e8352191f179
https://pubmed.ncbi.nlm.nih.gov/31245943
https://pubmed.ncbi.nlm.nih.gov/31245943
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 32(3)
To investigate the effects of β-sheet breaker peptide H102 on NF-κB signal pathway in brain of APP/PS1 double transgenic mice.Thirty 8-week-old APP/PS1 double transgenic mice were randomly divided into model group and treatment group. A group of C5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7403aa39dced9523f90e289bce3ab849
https://pubmed.ncbi.nlm.nih.gov/29931875
https://pubmed.ncbi.nlm.nih.gov/29931875
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 32(4)
To investigate the effects ofβ-sheet breaker peptide H102 on expression of synaptic plasticity associated proteins and learning and memory functions in double transgenic Alzheimer's disease(AD) mice,and to discuss its mechanisms.Thirty APP-swe/PS1dE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22457264bc465aaa98585a99fb158ab0
https://pubmed.ncbi.nlm.nih.gov/29931950
https://pubmed.ncbi.nlm.nih.gov/29931950
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 33(4)
To investigate the effect of β-sheet breaker peptide H102 on APP associated secretase in the hippocampus brain regions of APP/PS1 double transgenic mice(AD mice).Thirty 6-month-old APP/PS1 double transgenic mice were randomly divided into AD group a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a2c386e80841199f5f4e24dd12ed4e9
https://pubmed.ncbi.nlm.nih.gov/29926633
https://pubmed.ncbi.nlm.nih.gov/29926633
Autor:
Hua Tang, Fengxian Sun, Fang Jiang, Moxin Wan, Xiangyu Bo, Weiying Liu, Laixiang Lin, Shu-Mei Xu
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 8 (2018)
Frontiers in Pharmacology, Vol 8 (2018)
Background: Alzheimer's disease (AD), is a progressive neurodegenerative disease that is characterized by cognitive loss. Most researchers believe that aggregation and accumulation of β-amyloid peptides (Aβ) in brain cells are the central pathologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae1002ffb52111cf3336d82221f04a2
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 25(1)
To explore the single nucleotide polymorphism(SNP) of mitochondrial DNA (mtDNA) D-LOOP region in peripheral blood lymphocytes of immuno-related pancytopenia (IRP) patients and its correlation with immune parameters.The D-LOOP region in mitochondrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dbd79b2adf0b359c08e1dab2d7d9d1d
https://pubmed.ncbi.nlm.nih.gov/28245399
https://pubmed.ncbi.nlm.nih.gov/28245399
Autor:
Laixiang Lin, Kai-jun Zheng, Zhi-hong Ma, Shu-mei Xu, Ming Song, Xiang-yu Bo, Feng-Xian Sun, Yuan-zhen Tan, Juan Zhao, Mei Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112052 (2014)
PLoS ONE, Vol 9, Iss 11, p e112052 (2014)
β-amyloid hypothesis is the predominant hypothesis in the study of pathogenesis of Alzheimer's disease. This hypothesis claims that aggregation and neurotoxic effects of amyloid β (Aβ) is the common pathway in a variety of etiological factors for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1d424943e8a156be5db892fc057ec7
https://pubmed.ncbi.nlm.nih.gov/25372040
https://pubmed.ncbi.nlm.nih.gov/25372040
Publikováno v:
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 29(3)
To study the effect of combining the injection of beta-sheet breaker H102 with human umbilical cord mesenchymal stem cell (hUCMSC) on APP transgenic mice behavior, P-tau, apoptosis and the expression of relevant enzymes in the brain.APP transgenic mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28aaa80ec16d38e07fdb28993c81fc5d
https://pubmed.ncbi.nlm.nih.gov/23940958
https://pubmed.ncbi.nlm.nih.gov/23940958