Zobrazeno 1 - 10
of 392
pro vyhledávání: '"Shu-jen Chen"'
Autor:
Chung-Yu Huang, Kien-Thiam Tan, Shiu-Feng Huang, Yen-Jung Lu, Yeh-Han Wang, Shu-Jen Chen, Ka-Po Tse
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Hepatocellular carcinoma (HCC) is characterized by a notable sex disparity in incidence and tumor aggressiveness. Revealing differences in genetic landscapes between male and female HCCs may expand the understanding of sexual disparities mec
Externí odkaz:
https://doaj.org/article/795312c4f59046f8b53e8533911665f7
Autor:
Shang‐Hung Chen, Ka‐Po Tse, Yen‐Jung Lu, Shu‐Jen Chen, Yu‐Feng Tian, Kien Thiam Tan, Chien‐Feng Li
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Background Breast cancer is a heterogeneous disease categorized based on molecular characteristics, including hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) expression levels. The emergence of profiling technology
Externí odkaz:
https://doaj.org/article/556eec84f6ec4018be34d1e7a502c792
Autor:
Angel Chao, Shu-Jen Chen, Hua-Chien Chen, Kien Thiam Tan, Wen Hsiao, Shih-Ming Jung, Lan-Yan Yang, Kuan-Gen Huang, Hung-Hsueh Chou, Huei-Jean Huang, Ting-Chang Chang, An-Shine Chao, Yun-Hsien Lee, Ren-Chin Wu, Chyong-Huey Lai
Publikováno v:
Biomedical Journal, Vol 46, Iss 5, Pp 100563- (2023)
Background: We investigated whether mutations in plasma circulating tumor DNA (ctDNA) can provide prognostic insight in patients with different histological types of ovarian carcinoma. We also examined the concordance of mutations detected in ctDNA s
Externí odkaz:
https://doaj.org/article/3bcb0cd987684ff4b45d2cca18cdf02a
Autor:
Po-Han Lin, Ling-Ming Tseng, Yi-Hsuan Lee, Shou-Tung Chen, Dah-Cherng Yeh, Ming-Shen Dai, Liang-Chih Liu, Ming-Yang Wang, Chiao Lo, Stanley Chang, Kien Thiam Tan, Shu-Jen Chen, Sung-Hsin Kuo, Chiun-Sheng Huang
Publikováno v:
Journal of the Formosan Medical Association, Vol 121, Iss 12, Pp 2538-2547 (2022)
Background: The prognosis of triple-negative breast cancer (TNBC) is worse and a major proportion of TNBC expresses epidermal growth factor receptor (EGFR). Afatinib can inhibit EGFR signal pathway; however, its treatment effect for TNBC is unknown.
Externí odkaz:
https://doaj.org/article/33e09497336746968e55f30da7ec0b96
Autor:
Iwona Hirschler-Laszkiewicz, Fernanda Festa, Suming Huang, George-Lucian Moldovan, Claudia Nicolae, Ashna Dhoonmoon, Lei Bao, Kerry Keefer, Shu-jen Chen, Hong-Gang Wang, Joseph Y. Cheung, Barbara A. Miller
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Transient receptor potential channel melastatin 2 (TRPM2) is highly expressed in cancer and has an essential function in preserving viability through maintenance of mitochondrial function and antioxidant response. Here, the role of TRPM2 in
Externí odkaz:
https://doaj.org/article/4fbf757ed7af457bbd255a2db843529c
Autor:
John Wen‐Cheng Chang, Chien‐Jung Huang, Wen‐Kuan Huang, Yu‐Chao Wang, Jia‐Juan Hsieh, Yao‐Yu Chang, Yen‐Lin Huang, Chia‐Ling Wu, Yeh‐Han Wang, Shu‐Jen Chen, Kien Thiam Tan, Chiao‐Ping Chen, Chiao‐En Wu
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 8, Pp n/a-n/a (2023)
Abstract Objective Genomic biomarkers predicting immune checkpoint inhibitor (ICI) treatment outcomes for Asian metastatic melanoma have been rarely reported. This study presents data on next‐generation sequencing (NGS) and tumour microenvironment
Externí odkaz:
https://doaj.org/article/9d3e16d3182b40b6b8ab13363b85fb2d
Autor:
Ya-Ting Chen, Shu-Jen Chen, Chun-Yi Hu, Cheng-Di Dong, Chiu-Wen Chen, Reeta Rani Singhania, Shu-Ling Hsieh
Publikováno v:
Molecules, Vol 28, Iss 15, p 5679 (2023)
Fish bone fermented using Monascus purpureus (FBF) has total phenols and functional amino acids that contribute to its anti-oxidant and anti-inflammatory properties. Colorectal cancer, one of the most prevalent cancers and the third largest cause of
Externí odkaz:
https://doaj.org/article/75584f0f9f6342f0b824ff26f395e2e5
Autor:
Nina Lapke, Chien-Hung Chen, Ting-Chang Chang, Angel Chao, Yen-Jung Lu, Chyong-Huey Lai, Kien Thiam Tan, Hua-Chien Chen, Hsiao-Yun Lu, Shu-Jen Chen
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background Genetic alterations for epithelial ovarian cancer are insufficiently characterized. Previous studies are limited regarding included histologies, gene numbers, copy number variant (CNV) detection, and interpretation of pathway alte
Externí odkaz:
https://doaj.org/article/264108415813470b91d938e7123435dd
Autor:
Shih-Chieh Chang, Yi-Chun Lai, Cheng-Yu Chang, Li-Kuo Huang, Shu-Jen Chen, Kien Thiam Tan, Pei-Ning Yu, Jiun-I Lai
Publikováno v:
Translational Oncology, Vol 12, Iss 11, Pp 1425-1431 (2019)
Epidermal growth factor receptor- tyrosine kinase inhibitors (EGFR-TKI) are recommended first-line therapy for advanced non-small cell lung cancer (NSCLC) with sensitizing EGFR mutations. It is of clinical interest to identify concurrent genetic muta
Externí odkaz:
https://doaj.org/article/e12293159a2a4252acfcd79f50fdab8c
Autor:
Joshua J Sims, Jenny A Greig, Kristofer T Michalson, Sharon Lian, R Alexander Martino, Rosemary Meggersee, Kevin B Turner, Kalyani Nambiar, Cecilia Dyer, Christian Hinderer, Makoto Horiuchi, Hanying Yan, Xin Huang, Shu-Jen Chen, James M Wilson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009544 (2021)
SARS-CoV-2 variants have emerged with enhanced pathogenicity and transmissibility, and escape from pre-existing immunity, suggesting first-generation vaccines and monoclonal antibodies may now be less effective. Here we present an approach for preven
Externí odkaz:
https://doaj.org/article/1456eae8f81744b0b130542e55e5bbc3