Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shu-Yan Zhou"'
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Background Human induced pluripotent stem cells (hiPSCs) represent a potentially unlimited source of pancreatic endocrine lineage cells. Although insulin-producing β cells derived from hiPSCs have been successfully induced, much work remain
Externí odkaz:
https://doaj.org/article/28ad016137b949608760b78ec988fda4
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94548 (2014)
Islet transplantation has considerable potential as a cure for diabetes. However, the difficulties that arise from inflammation and the immunological rejection of transplants must be addressed for islet transplantation to be successful. Alpha 1-antit
Externí odkaz:
https://doaj.org/article/f7b8bc46376c4f009e18cd7c563950bf
Autor:
Yongxia Zhu, Rong Hu, Tinghong Ye, Xiuli Wu, Wei Wei, Hualong He, Luoting Yu, Xi Hu, Qi-Wei Wang, Zhihao Liu, Ning-Yu Wang, Xingping Su, Shu-Yan Zhou, Qiangsheng Zhang
Publikováno v:
Journal of Medicinal Chemistry. 64:2829-2848
EZH2 mediates both PRC2-dependent gene silencing via catalyzing H3K27me3 and PRC2-independent transcriptional activation in various cancers. Given its oncogenic role in cancers, EZH2 has constituted a compelling target for anticancer therapy. However
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Human induced pluripotent stem cells (hiPSCs) represent a potentially unlimited source of pancreatic endocrine lineage cells. Although insulin-producing β cells derived from hiPSCs have been successfully induced, much work remains to be d
Autor:
Shu-Yan, Zhou, Xin-Yi, Chen, Yan, Chen, Na-Na, Meng, Xin, Tao, Hua-Long, He, Zhi-Hao, Liu, Ning-Yu, Wang, Luo-Ting, Yu
Publikováno v:
Die Pharmazie. 76(8)
Drug resistance caused by the extreme genetic variability of zhe hepatitis C virus has rendered effective combinations of drugs indispensable in the treatment of chronic hepatitis C (CHC). Herein, we developed a fixed-dose combination (FDC) treatment
Autor:
Shu-Yan Zhou, Jing Ren, Ying Xu, Zhanzhan Feng, Juan Rong, Qiang Xue, Wei Wei, Kun-Lin Liu, Yao-Jie Shi, Ningyu Wang, Luoting Yu
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(19)
Bromodomain-containing protein 4 (BRD4), a member of the bromodomain and extra-terminal (BET) family, has been recognized as an attractive candidate target for the treatment targeting gene transcription in several types of cancers. In this study, two
Publikováno v:
Experimental Cell Research. 340:227-237
Human induced pluripotent stem cells (hiPSCs) are capable of unlimited self-renewal and can generate nearly all cells in the body. Changes induced by different LSD1 activities on the regulation of hiPSC self-renewal and differentiation and the mechan
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 25(2)
To investigate the effects of Agkistrodon acutus venom protein C activator(PCA) on ultrastructure of human umbilical vein endothelial cells(HUVEC), and the levels of tissue factor(TF), vascular von Willebrand factor (vWF) and endothelin-1 secreted by
Autor:
Fu-Rong Li, Shu-Yan Zhou, Tao Ye, Hui Qi, Tao Chen, Chun-Yan Deng, Yunshuai Wang, Hong-Jie Yan
Publikováno v:
Journal of Cellular Biochemistry. 114:2231-2239
Mesenchymal stem cells (MSCs) are self-renewing cells that exhibit differentiation capacity and immune regulation ability. These versatile cells have a wide range of potential applications. However, the spontaneous differentiation and aging of MSCs d
Autor:
Hai Xuan Chen, Dong Lei Ma, Qiu Ying Liu, Bi Bo Ruan, Wang Yifei, Yi Zhang, Peng Jun Zhou, Zhe Ren, Dan-Dan Xu, Hai Zhao Yan, Yuting Liu, Shu Yan Zhou, Wu Yu Fu, Sheng Wang, Rong Zhang, Ying Wang, Xiaoyan Wang, Li Zhang, Xiao Wang, Zhong Liu
Publikováno v:
Scientific Reports
Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-reg