Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Shu-Xiang Cui"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 16, Iss , Pp 105-117 (2019)
The important role of insulin-like growth factor-1 receptor (IGF-1R) in tumorigenesis has been well established. The classical model involves IGF-1R binding to IGF-1/2, the following activation of PI3K-Akt-signaling cascades, driving cell proliferati
Externí odkaz:
https://doaj.org/article/1d84a5136e4d4d57b298d29e2f944057
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundM10 is a derivative of Myricetin by adding a hydrophilic glycosylation group. Our previous study revealed that M10 by oral administration prevented colitis-associated colonic cancer (CAC) through attenuating endoplasmic reticulum stress in
Externí odkaz:
https://doaj.org/article/45e480a539b54503843c7e623dcebcd4
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 1, Pp 201-212 (2015)
Background/Aims: Des-gamma-carboxy prothrombin (DCP), an aberrant prothrombin produced by hepatocellular carcinoma (HCC) cells, is known as a marker for HCC. Recent studies indicated that high levels of DCP are associated with the malignant potential
Externí odkaz:
https://doaj.org/article/60340bac9ca64c3ba77c10dd03f90464
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 3, Pp 903-915 (2014)
Des-γ-carboxy prothrombin (DCP) is a prothrombin precursor produced in hepatocellular carcinoma (HCC). Because of deficiency of vitamin K or γ-glutamyl carboxylase in HCC cells, the 10 glutamic acid (Glu) residues in prothrombin precursor did not c
Externí odkaz:
https://doaj.org/article/04e352a1c8a844ef9c795c81a998a87a
Autor:
Hui-Ping Liu, Zu-Hua Gao, Shu-Xiang Cui, De-Fu Sun, Yan Wang, Cui-Rong Zhao, Hong-Xiang Lou, Xian-Jun Qu
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33243 (2012)
BACKGROUND: Mutation of tumor suppressor gene, adenomatous polyposis coli (APC), is the primary molecular event in the development of most intestinal carcinomas. Animal model with APC gene mutation is an effective tool for study of preventive approac
Externí odkaz:
https://doaj.org/article/32fbc34216ca4f66bb36d2eeb875ad1a
Autor:
Juan, Yang, Rong-Rong, Miao, Ya-Nan, Li, Ting, Pan, Shu-Hua, Wu, Xian-Jun, Qu, Shu-Xiang, Cui
Publikováno v:
Acta Pharmacologica Sinica. 43:2967-2976
Atypical chemokine receptor 3 (ACKR3) has emerged as a key player in various biological processes. Its atypical "intercepting receptor" properties have established ACKR3 as the major regulator in the pathophysiological processes in many diseases. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25b3ba2276cfd4b1c2850a4da5fc65b
https://doi.org/10.1038/s41401-022-00901-x
https://doi.org/10.1038/s41401-022-00901-x
Publikováno v:
Toxicology Letters. 346:7-15
Our previous studies found that M10, a myricetin-3-O-β-d-lactose sodium salt, possessed higher effects of ameliorating ulcerative colitis (UC) than Myricetin in mice. Here, we aim to investigate whether the inhibition of UC is the consequence of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046b505827064814ec570300c24089c5
https://doi.org/10.1016/j.toxlet.2021.03.009
https://doi.org/10.1016/j.toxlet.2021.03.009
Autor:
Shu-Xiang Cui, Xiaohui Wang, Xinfeng Yu, Mahan Si, Dong Wang, Shiyue Sun, Xian-Jun Qu, Juan Yang, Haochen Wu
Publikováno v:
Cancer Letters. 525:200-202
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc4a7a7bbb20353f07c50555c1767f4
https://doi.org/10.1016/j.canlet.2021.11.010
https://doi.org/10.1016/j.canlet.2021.11.010
Autor:
Shu-Xiang Cui, Yuan-Hang Liu, Shu-Hua Wu, Xinfeng Yu, Xiao-Hui Liu, Shi-Yue Sun, Xian-Jun Qu, Xue-Tao Hu, Yang-Yang Li, Yue-Ying Zhang
Publikováno v:
British Journal of Pharmacology. 178:2351-2369
Background and purpose It is well known that microsatellite instability-high (MSI-H) is associated with 5-fluorouracil (5-FU) resistance in colorectal cancer. MSI-H is the phenotype of DNA mismatch repair deficiency (MMR-D), mainly occurring due to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003e301afe4ac5b8838574e2489dddc5
https://doi.org/10.1111/bph.15422
https://doi.org/10.1111/bph.15422
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(8)
Conjugated bile acids (CBAs) play major roles in hepatic gene regulation via nuclear S1P-inhibited histone deacetylase (HDACs). Gut microbiota modifies bile acid pool to generate CBAs and then CBAs returned to liver to regulate hepatic genes, fatty l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6433d017b31c19cddd29a9fba40fa90
https://pubmed.ncbi.nlm.nih.gov/35792869
https://pubmed.ncbi.nlm.nih.gov/35792869