Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Shu-Wing Ng"'
Autor:
Cindy M. Yamamoto, Melanie L. Oakes, Taku Murakami, Michael G. Muto, Ross S. Berkowitz, Shu-Wing Ng
Publikováno v:
Journal of Ovarian Research, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Background Extracellular vesicles (EVs) are considered as a new class of resources for potential biomarkers. We analyzed expression of specific mRNA and miRNA in EVs derived from ovarian cancer ascites and the ideal controls, peritoneal flui
Externí odkaz:
https://doaj.org/article/f2694fda46c9428198be1af1721a81d8
Autor:
Junzheng Yang, Yilan Zhou, Shu-Kay Ng, Kuan-Chun Huang, Xiaoyan Ni, Pui-Wah Choi, Kathleen Hasselblatt, Michael G. Muto, William R. Welch, Ross S. Berkowitz, Shu-Wing Ng
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-12 (2017)
Abstract Background Ovarian cancer is the leading cause of death among gynecologic diseases in Western countries. We have previously identified a miR-200-E-cadherin axis that plays an important role in ovarian inclusion cyst formation and tumor invas
Externí odkaz:
https://doaj.org/article/409ede4f9cf34fedb20144c2c0aa4589
Autor:
Shu-Wing Ng, Gabriella A. Norwitz, Mihaela Pavlicev, Tamara Tilburgs, Carlos Simón, Errol R. Norwitz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4092 (2020)
Interventions to prevent pregnancy complications have been largely unsuccessful. We suggest this is because the foundation for a healthy pregnancy is laid prior to the establishment of the pregnancy at the time of endometrial decidualization. Humans
Externí odkaz:
https://doaj.org/article/6dc01f188f834b218f85f4bed320e449
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3283 (2019)
Iron is an essential element for the survival of most organisms, including humans. Demand for iron increases significantly during pregnancy to support growth and development of the fetus. Paradoxically, epidemiologic studies have shown that excessive
Externí odkaz:
https://doaj.org/article/251c23fe0a8c46bfa29c367513fc91a2
Autor:
Taymaa May, Junzheng Yang, Melina Shoni, Shubai Liu, Housheng He, Reddy Gali, Shu-Kay Ng, Christopher Crum, Ross S. Berkowitz, Shu-Wing Ng
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 6, Pp 600-608 (2013)
INTRODUCTION: Ovarian cancer is the leading cause of mortality from gynecological malignancy despite advancements in novel therapeutics. We have recently demonstrated that the transcriptional co-repressor C-terminal binding protein 2 (CtBP2) is overe
Externí odkaz:
https://doaj.org/article/47840961fffe4ec6a7043dfacf7c3af8
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 3, Pp 5367-5379 (2013)
Endometriosis is classically defined as the presence of endometrial glands and stroma outside of the endometrial lining and uterine musculature. With an estimated frequency of 5%–10% among women of reproductive age, endometriosis is a common gyneco
Externí odkaz:
https://doaj.org/article/06ec48d0587e4da28a639cf0508db072
Autor:
Pui-Wah Choi, Shu-Wing Ng
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 6, p 1207 (2017)
The majority of studies on microRNA-200 family members (miR-200s) in human cancers are based on the premise that miR-200s maintain epithelial cell integrity by suppressing epithelial-mesenchymal transition (EMT) through direct inhibition of mesenchym
Externí odkaz:
https://doaj.org/article/20f703411e25466bb04e8c690b79bf3f
Autor:
Sze Kei Liu, Kwong Kwok Wong, Shu-Wing Ng, Chun Kin Chow, Winston Patrick Kuo, Fang Xie, Errol R. Norwitz, Ross S. Berkowitz, Joseph Kwong, Karen Hales, Dale B. Hales, Abbas Bahrampour, Shu-Kay Ng, Pui-Wah Choi, Wei Qiu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
MicroRNA-200 (miR-200) family is highly expressed in ovarian cancer. We evaluated the levels of family members relative to the internal control miR-103a in ovarian cancer and control blood specimens collected from American and Hong Kong Chinese insti
Autor:
Pui-Wah Choi, Dale B. Hales, Kin Ming Kwan, William R. Welch, Shu-Kay Ng, Ross S. Berkowitz, Jamie S. L. Kwok, Karen Hales, Junzheng Yang, Ka Kui Tong, Shubai Liu, Shu-Wing Ng, Wing-Ping Fong, Christopher P. Crum, Stephen Kwok-Wing Tsui, Wai Wing So
Publikováno v:
Oncogene. 39:4045-4060
Epidemiologic and histopathologic findings and the laying hen model support the long-standing incessant ovulation hypothesis and cortical inclusion cyst involvement in sporadic ovarian cancer development. MicroRNA-200 (miR-200) family is highly expre
Publikováno v:
Reproductive Sciences. 27:1383-1390
Iron is an essential element for cell survival, and iron deficiency is a known risk factor for many reproductive disorders. Paradoxically, such disorders are also seen more commonly under conditions of iron excess. Here, we focus on the problem of ir