Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Shu-Qun Shi"'
Autor:
Shu-qun Shi, Carrie E. Mahoney, Pavel Houdek, Wenling Zhao, Matthew P. Anderson, Xinming Zhuo, Arthur Beaudet, Alena Sumova, Thomas E. Scammell, Carl Hirschie Johnson
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Normal neurodevelopment requires precise expression of the key ubiquitin ligase gene Ube3a. Comparing newly generated mouse models for Ube3a downregulation (models of Angelman syndrome) vs. Ube3a upregulation (models for autism), we find reciprocal e
Externí odkaz:
https://doaj.org/article/b41a57afdeb4418496ca592e63b055fe
Autor:
Martin R Ralph, Shu-Qun Shi, Carl H Johnson, Pavel Houdek, Tenjin C Shrestha, Priya Crosby, John S O'Neill, Martin Sládek, Adam R Stinchcombe, Alena Sumová
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008987 (2021)
Modification of the Per2 clock gene in mPer2Luc reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and dissociates into two distinct components in constant light. Rhythms exhibit increased bimodal
Externí odkaz:
https://doaj.org/article/e98516d1343e4612b43b371cca13078b
Autor:
Jie Yang, Derrick Cumberbatch, Samuel Centanni, Shu-qun Shi, Danny Winder, Donna Webb, Carl Hirschie Johnson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The coupling of optogenetics with fluorescent Ca2+ sensors is confounded by sensitivity of optogenetic probes to light used to excite the sensors. Here the authors develop a Ca2+ sensor based on bioluminescence resonance energy transfer (BRET) that m
Externí odkaz:
https://doaj.org/article/38ae3b777e7041d28342246b480b0c17
Autor:
Shu-Qun, Shi, Carrie E, Mahoney, Pavel, Houdek, Wenling, Zhao, Matthew P, Anderson, Xinming, Zhuo, Arthur, Beaudet, Alena, Sumova, Thomas E, Scammell, Carl Hirschie, Johnson
Publikováno v:
Frontiers in behavioral neuroscience. 16
Normal neurodevelopment requires precise expression of the key ubiquitin ligase gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f8b2e220ce886985c159c4236e0b0d4
https://pubmed.ncbi.nlm.nih.gov/35401134
https://pubmed.ncbi.nlm.nih.gov/35401134
Autor:
Carrie E. Mahoney, Alena Sumová, Carl Hirschie Johnson, Xinming Zhuo, Shu-qun Shi, Thomas E. Scammell, Wenling Zhao, Arthur L. Beaudet, Matthew P. Anderson, Pavel Houdek
Normal neurodevelopment requires precise expression of the key ubiquitin ligase gene Ube3a. Comparing newly generated mouse models for Ube3a down-regulation (models of Angelman syndrome) vs. Ube3a up-regulation (models for autism), we find reciprocal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd45216196818732840bd6d6a64eea4d
https://doi.org/10.1101/2021.10.26.465956
https://doi.org/10.1101/2021.10.26.465956
Autor:
Priya Crosby, John S. O’Neill, Adam R. Stinchcombe, Carl Hirschie Johnson, Shu-qun Shi, Martin Sládek, Tenjin C. Shrestha, Alena Sumová, Pavel Houdek, Martin R. Ralph
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1008987 (2021)
PLoS Computational Biology
PLoS Computational Biology
Modification of the Per2 clock gene in mPer2Luc reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and dissociates into two distinct components in constant light. Rhythms exhibit increased bimodal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ab2a79067a0660398fdaa507e7ecf5
Autor:
Shu-qun Shi, Carl Hirschie Johnson
Publikováno v:
Current opinion in behavioral sciences. 25
Sleep disturbances are common in people with monogenic neurological disorders and they dramatically affect the life of individuals with the disorders and their families. The associated sleep problems are probably caused by multiple factors that have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c41ec332948e3224d1622920978b1c
https://pubmed.ncbi.nlm.nih.gov/31289731
https://pubmed.ncbi.nlm.nih.gov/31289731
Autor:
Samuel W. Centanni, Jie Yang, Derrick Cumberbatch, Danny G. Winder, Shu-qun Shi, Carl Hirschie Johnson, Donna J. Webb
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications
Optogenetic techniques allow intracellular manipulation of Ca++ by illumination of light-absorbing probe molecules such as channelrhodopsins and melanopsins. The consequences of optogenetic stimulation would optimally be recorded by non-invasive opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b926d8e235c5866c075b76a6f1d48ff7
https://doi.org/10.1038/ncomms13268
https://doi.org/10.1038/ncomms13268
Autor:
Akiko Hida, David H. Wasserman, Shin Yamazaki, Shu-qun Shi, Owen P. McGuinness, Carl Hirschie Johnson
Publikováno v:
Current Biology. 20:316-321
Summary Most of the central circadian clock genes in the mouse exist as paralog pairs ( Per1 and Per2 , Cry1 and Cry2 , Clock and Npas2 ) in which each gene of the pair must be knocked out to confer arrhythmicity [1–3]. The only exception to this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da9bf754d85bc5feb7c3103c10da6994
https://doi.org/10.1016/j.cub.2009.12.034
https://doi.org/10.1016/j.cub.2009.12.034