Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Shu-Qin Ding"'
Autor:
Jing-Lu Li, Gui-Qiang Fu, Yang-Yang Wang, Ming-Ming Bian, Yao-Mei Xu, Lin Zhang, Yu-Qing Chen, Nan Zhang, Shu-Qin Ding, Rui Wang, Rui Fang, Jie Tang, Jian-Guo Hu, He-Zuo Lü
Publikováno v:
PeerJ, Vol 11, p e14929 (2023)
Background Following spinal cord injury (SCI), a large number of peripheral monocytes infiltrate into the lesion area and differentiate into macrophages (Mø). These monocyte-derived Mø are very difficult to distinguish from the local activated micr
Externí odkaz:
https://doaj.org/article/9c8620617c1b4f0cb3d572de2619f0bb
Autor:
Jing Chen, Yu-Qing Chen, Yu-Jiao Shi, Shu-Qin Ding, Lin Shen, Rui Wang, Qi-Yi Wang, Cheng Zha, Hai Ding, Jian-Guo Hu, He-Zuo Lü
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1836-1847 (2021)
Inflammation is a major cause of neuronal injury after spinal cord injury. We hypothesized that inhibiting caspase-1 activation may reduce neuroinflammation after spinal cord injury, thus producing a protective effect in the injured spinal cord. A mo
Externí odkaz:
https://doaj.org/article/118f003fb4354b48ae1e667daa7ba168
Autor:
Yu-Qing Chen, Sai-Nan Wang, Yu-Jiao Shi, Jing Chen, Shu-Qin Ding, Jie Tang, Lin Shen, Rui Wang, Hai Ding, Jian-Guo Hu, He-Zuo Lü
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background After spinal cord injury (SCI), destructive immune cell subsets are dominant in the local microenvironment, which are the important mechanism of injury. Studies have shown that inflammasomes play an important role in the inflammat
Externí odkaz:
https://doaj.org/article/a51e96b6c7b649b582219571efe11df0
Autor:
Sai-Nan Wang, Xue-Yan Guo, Jie Tang, Shu-Qin Ding, Lin Shen, Rui Wang, Shan-Feng Ma, Jian-Guo Hu, He-Zuo Lü
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 3, Pp 542-552 (2019)
In traumatic brain injury, absent in melanoma 2 (AIM2) has been demonstrated to be involved in pyroptotic neuronal cell death. Although the pathophysiological mechanism of spinal cord injury is similar to that of brain injury, the expression and cell
Externí odkaz:
https://doaj.org/article/29e2d5ba6b924690b4f7017a6a07c61f
Autor:
Bo Zhang, Ling-Ling Yang, Shu-Qin Ding, Jing-Jing Liu, Yan-Hong Dong, Yan-Ting Li, Nan Li, Xiao-Jun Zhao, Chang-Ling Hu, Yiping Jiang, Xue-Qin Ma
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Given the limitations of existing therapeutic agents for treatment of postmenopausal osteoporosis, there still remains a need for more options with both efficacy and less adverse effects. Cistanche deserticola Y. C. Ma is known as a popular tonic her
Externí odkaz:
https://doaj.org/article/f84536d5e89643e58303ad4190bbf8c4
Autor:
Shu-Qin Ding, Lin Shen, Rui Wang, He-Zuo Lü, Jian-Guo Hu, Jing Chen, Yu-Jiao Shi, Hai Ding, Cheng Zha, Qi-Yi Wang, Yu-Qing Chen
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1836-1847 (2021)
Neural Regeneration Research
Neural Regeneration Research
Inflammation is a major cause of neuronal injury after spinal cord injury. We hypothesized that inhibiting caspase-1 activation may reduce neuroinflammation after spinal cord injury, thus producing a protective effect in the injured spinal cord. A mo
Autor:
Rui Wang, Lin Shen, Shu-Qin Ding, Jin Xi, Fengchao Wang, Jie Tang, Qi Qi, Yu-Jiao Shi, Jian-Guo Hu, Jing Chen, He-Zuo Lü, Fei-Xiang Duan
Publikováno v:
Experimental Biology and Medicine. 244:1680-1687
Spinal cord injury (SCI), a serious neurological disease, has few therapeutic interventions. A small molecule, P7C3, has been confirmed to play a role in neuroprotection of some neurological diseases. But the effect of P7C3 on acute SCI has not been
Background The myeloid cells play a vital role in health and disease of central nervous system (CNS). However, how to clearly distinguish them is still a knotty problem. At present, single-cell RNA Sequencing (scRNA-Seq) technology can sequence thous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d24340237667ba76bc1430cf12bd94b
https://doi.org/10.21203/rs.3.rs-1071141/v1
https://doi.org/10.21203/rs.3.rs-1071141/v1
Autor:
Yu-Jiao Shi, Wen-Jie Sheng, Meng-Tong Xue, Fei-Xiang Duan, Lin Shen, Shu-Qin Ding, Qi-Yi Wang, Rui Wang, He-Zuo Lü, Jian-Guo Hu
Publikováno v:
Gene. 823
We have previously reported that morroniside promoted motor activity after spinal cord injury (SCI) in rats. However, the mechanism by which morroniside induces recovery of injured spinal cord (SC) remains unknown. In the current study, RNA sequencin
Autor:
Lin Shen, Shu-Qin Ding, Yan Wu, Sai-Nan Wang, Xue-Yan Guo, Jian-Guo Hu, Yu-Hong Lin, Jie Tang, Rui Wang, He-Zuo Lü
Publikováno v:
Genomics. 111:986-996
The underlying mechanisms of macrophage polarization have been detected by genome-wide transcriptome analysis in a variety of mammals. However, the transcriptome profile of rat genes in bone marrow-derived macrophages (BMM) at different activation st