Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Shu-Hsien Sheu"'
Autor:
Thomas Delgado, Ronald S. Petralia, David W. Freeman, Miloslav Sedlacek, Ya-Xian Wang, Stephan D. Brenowitz, Shu-Hsien Sheu, Jeffrey W. Gu, Dimitrios Kapogiannis, Mark P. Mattson, Pamela J. Yao
Publikováno v:
Biology Open, Vol 8, Iss 8 (2019)
Serial-section electron microscopy such as FIB-SEM (focused ion beam scanning electron microscopy) has become an important tool for neuroscientists to trace the trajectories and global architecture of neural circuits in the brain, as well as to visua
Externí odkaz:
https://doaj.org/article/a219570d5c1b48e69bca21380b0e4090
Autor:
Alban Latremoliere, Long Cheng, Michelle DeLisle, Chen Wu, Sheena Chew, Elizabeth B. Hutchinson, Andrew Sheridan, Chloe Alexandre, Frederic Latremoliere, Shu-Hsien Sheu, Sara Golidy, Takao Omura, Eric A. Huebner, Yanjie Fan, Mary C. Whitman, Elaine Nguyen, Crystal Hermawan, Carlo Pierpaoli, Max A. Tischfield, Clifford J. Woolf, Elizabeth C. Engle
Publikováno v:
Cell Reports, Vol 24, Iss 7, Pp 1865-1879.e9 (2018)
Summary: We generated a knockout mouse for the neuronal-specific β-tubulin isoform Tubb3 to investigate its role in nervous system formation and maintenance. Tubb3−/− mice have no detectable neurobehavioral or neuropathological deficits, and upr
Externí odkaz:
https://doaj.org/article/39973573a0814e0c95602d286adca792
Publikováno v:
eLife, Vol 7 (2018)
Mutations in the polycystin genes, PKD1 or PKD2, results in Autosomal Dominant Polycystic Kidney Disease (ADPKD). Although a genetic basis of ADPKD is established, we lack a clear understanding of polycystin proteins’ functions as ion channels. Thi
Externí odkaz:
https://doaj.org/article/1316725f3ce14c489a7b1855b8cfe8a7
Publikováno v:
eLife, Vol 6 (2017)
In many parts of the nervous system, signals pass across multiple synaptic relays on their way to a destination, but little is known about how these relays form and the function they serve. To get some insight into this question we ask how the connec
Externí odkaz:
https://doaj.org/article/c387665786b0455da166c510465a3184
Autor:
Shu-Hsien Sheu, Srigokul Upadhyayula, Vincent Dupuy, Song Pang, Fei Deng, Jinxia Wan, Deepika Walpita, H. Amalia Pasolli, Justin Houser, Silvia Sanchez-Martinez, Sebastian E. Brauchi, Sambashiva Banala, Melanie Freeman, C. Shan Xu, Tom Kirchhausen, Harald F. Hess, Luke Lavis, Yulong Li, Séverine Chaumont-Dubel, David E. Clapham
Publikováno v:
Cell
Cell, 2022, 185 (18), pp.3390-3407. ⟨10.1016/j.cell.2022.07.026⟩
Cell, 2022, 185 (18), pp.3390-3407. ⟨10.1016/j.cell.2022.07.026⟩
International audience; Chemical synapses between axons and dendrites mediate neuronal intercellular communication. Here, we describe a synapse between axons and primary cilia: the axo-ciliary synapse. Using enhanced focused ion beam-scanning electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68741624c921623cc3a64eb6abe54391
https://hal.science/hal-03796396
https://hal.science/hal-03796396
Autor:
David E. Clapham, Srigokul Upadhyayula, C. Shan Xu, Andrew L. Lemire, Deepika Walpita, Justin Houser, Luke D. Lavis, Lihua Wang, Vincent Dupuy, Silvia Sanchez-Martinez, Song Pang, Sebastian Brauchi, Shu-Hsien Sheu, Fei Deng, H. Amalia Pasolli, Yulong Li, Séverine Chaumont-Dubel, Sambashiva Banala, Tom Kirchhausen, Jin-Xia Wan, Melanie Freeman, Harald F. Hess
SummaryChemical synapses between axons and dendrites mediate much of the brain’s intercellular communication. Here we describe a new kind of synapse – the axo-ciliary synapse - between axons and primary cilia. By employing enhanced focused ion be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d1d99275313e27b5339eed176e31211
https://doi.org/10.1101/2021.09.27.461878
https://doi.org/10.1101/2021.09.27.461878
Publikováno v:
Journal of the American Chemical Society. 141:13734-13738
Targeting small-molecule fluorescent indicators using genetically encoded protein tags yields new hybrid sensors for biological imaging. Optimization of such systems requires redesign of the synthetic indicator to allow cell-specific targeting withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d25bd24f0b25328d3b4d4729246e88d
https://doi.org/10.1021/jacs.9b06092
https://doi.org/10.1021/jacs.9b06092
Publikováno v:
Journal of the American Chemical Society. 141(35)
Targeting small-molecule fluorescent indicators using genetically encoded protein tags yields new hybrid sensors for biological imaging. Optimization of such systems requires redesign of the synthetic indicator to allow cell-specific targeting withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7253368df9972d8633ff18382fd414f3
https://pubmed.ncbi.nlm.nih.gov/31430138
https://pubmed.ncbi.nlm.nih.gov/31430138
Autor:
Pamela J. Yao, David W. Freeman, Mark P. Mattson, Stephan D. Brenowitz, Jeffrey Gu, Ronald S. Petralia, Dimitrios Kapogiannis, Miloslav Sedlacek, Ya-Xian Wang, Thomas E. Delgado, Shu-Hsien Sheu
Publikováno v:
Biology Open
Biology Open, Vol 8, Iss 8 (2019)
Biology Open, Vol 8, Iss 8 (2019)
Serial-section electron microscopy such as FIB-SEM (focused ion beam scanning electron microscopy) has become an important tool for neuroscientists to trace the trajectories and global architecture of neural circuits in the brain, as well as to visua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1401bdca4de8fa829f4f7800bd063ce
https://pubmed.ncbi.nlm.nih.gov/31362947
https://pubmed.ncbi.nlm.nih.gov/31362947
Autor:
Sung-Jan Lin, Yu-Hua Tseng, Chih-Lung Chen, Edrick Tai Yu Lin, Sabrina Mai-Yi Fan, Shu-Hsien Sheu, Bing Zhang, Farnaz Shamsi, Ya-Chieh Hsu, H. Amalia Pasolli, Pai Chi Tsai, Meryem Gonzalez-Celeiro, Steven Assaad, Megan He, Yulia Shwartz
Publikováno v:
Cell. 182(3)
Piloerection (goosebumps) requires concerted actions of the hair follicle, the arrector pili muscle (APM), and the sympathetic nerve, providing a model to study interactions across epithelium, mesenchyme, and nerves. Here, we show that APMs and sympa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0438cf284cd9017a6c8bab43f9ed392
https://pubmed.ncbi.nlm.nih.gov/32763185
https://pubmed.ncbi.nlm.nih.gov/32763185