Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shu-Ching M. Wang"'
Publikováno v:
Journal of Molecular Endocrinology. 62:R223-R237
Breast cancer is a heterogeneous disease, and the complexity of breast carcinogenesis is associated with epigenetic modification. There are several major classes of epigenetic enzymes that regulate chromatin activity. This review will focus on the ni
Autor:
Shu-Ching M. Wang, Zewen K. Tuong, Emily Shao, Joel M. Goode, Tae Gyu Oh, George E.O. Muscat, Michael A. Pearen
Publikováno v:
Molecular Endocrinology. 30:660-676
Skeletal muscle remodels metabolic capacity, contractile and exercise phenotype in response to physiological demands. This adaptive remodeling response to physical activity can ameliorate/prevent diseases associated with poor diet and lifestyle. Our
Autor:
Christine L. Clarke, Tae Gyu Oh, Bipul R. Acharya, Shu-Ching M. Wang, Alpha S. Yap, George E.O. Muscat, Joel M. Goode, J. Dinny Graham
Publikováno v:
EBioMedicine
We have previously reported that RORγ expression was decreased in ER − ve breast cancer, and increased expression improves clinical outcomes. However, the underlying RORγ dependent mechanisms that repress breast carcinogenesis have not been eluci
Publikováno v:
Endocrinology. 158(3)
Breast cancer is a heterogeneous disease and its complexity has hindered the development of efficacious treatments targeting all breast cancer subtypes. Many studies have linked the diversity of breast carcinogenesis and metastasis to aberrant epigen
Autor:
Patrick Lau, Rebecca L. Fitzsimmons, George E.O. Muscat, Shu-Ching M. Wang, Adriane Lechtken, Suryaprakash Raichur
Publikováno v:
Journal of Biological Chemistry. 283:18411-18421
Homozygous staggerer mice (sg/sg) display decreased and dysfunctional retinoic acid receptor-related orphan receptor α (RORα) expression. We observed decreases in serum (and liver) triglycerides and total and high density lipoprotein serum choleste
Autor:
Shu-Ching M. Wang, Uwe Dressel, Peter Bailey, Ronald M. Evans, George E.O. Muscat, Michael Downes
Publikováno v:
Journal of Biological Chemistry. 276:17007-17013
The overlapping expression profile of MEF2 and the class-II histone deacetylase, HDAC7, led us to investigate the functional interaction and relationship between these regulatory proteins. HDAC7 expression inhibits the activity of MEF2 (-A, -C, and -
Publikováno v:
Endocrinology. :en.2016-1716
Breast cancer is a heterogeneous disease and its complexity has hindered the development of efficacious treatments targeting all breast cancer subtypes. Many studies have linked the diversity of breast carcinogenesis and metastasis to aberrant epigen
Autor:
Patrick, Lau, Rebecca L, Fitzsimmons, Suryaprakash, Raichur, Shu-Ching M, Wang, Adriane, Lechtken, George E O, Muscat
Publikováno v:
The Journal of biological chemistry. 283(26)
Homozygous staggerer mice (sg/sg) display decreased and dysfunctional retinoic acid receptor-related orphan receptor alpha (RORalpha) expression. We observed decreases in serum (and liver) triglycerides and total and high density lipoprotein serum ch