Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shu-Cheng Wan"'
Autor:
Liang Zhang, An Song, Qi-Chao Yang, Shu-Jin Li, Shuo Wang, Shu-Cheng Wan, Jianwei Sun, Ryan T. K. Kwok, Jacky W. Y. Lam, Hexiang Deng, Ben Zhong Tang, Zhi-Jun Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Immunogenic programmed cell death, such as pyroptosis and ferroptosis, efficiently induces an acute inflammatory response and boosts antitumor immunity. However, the exploration of dual-inducers, particularly nonmetallic inducers, capable of
Externí odkaz:
https://doaj.org/article/27e34f63e59949f894cba2fc41fe9ae4
Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer
Autor:
Qi-Chao Yang, Shuo Wang, Yuan-Tong Liu, An Song, Zhi-Zhong Wu, Shu-Cheng Wan, Hui-Min Li, Zhi-Jun Sun
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106916- (2023)
Summary: Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been demonstrated to play a critical role in regulating cholesterol homeostasis and T cell antitumor immunity. However, the expression, function, and therapeutic value of PCSK9 in hea
Externí odkaz:
https://doaj.org/article/6c9538931e2b41bb8241871ed8a29bb0
Autor:
Meng-Jie Zhang, Meng-Yun Liang, Shao-Chen Yang, Xian-Bin Ma, Shu-Cheng Wan, Qi-Chao Yang, Shuo Wang, Zhigang Xu, Zhi-Jun Sun
Publikováno v:
Chemical Communications. 59:932-935
CDNPs, combined with BRAFi and Cox2i, induced pyroptosis to enhance cancer immunotherapy and act synergistically with anti-PD-1 therapy.
Autor:
Shuo Wang, Zhi-Zhong Wu, Su-Wen Zhu, Shu-Cheng Wan, Meng-Jie Zhang, Bo-Xin Zhang, Qi-Chao Yang, Yao Xiao, Hao Li, Liang Mao, Zhi-Yong Wang, J. Silvio Gutkind, Zhi-Jun Sun
Publikováno v:
Molecular Therapy.
Autor:
Meng-Jie Zhang, Jie Liu, Shu-Cheng Wan, Jia-Xing Li, Shuo Wang, Nyimi Bushabu Fidele, Cong-Fa Huang, Zhi-Jun Sun
Purpose Cysteine-rich protein 2 (CSRP2), as a newly discovered oncogene, is overexpressed in several cancers. However, the specific role of CSRP2 and its potential mechanism remain incompletely understood in head and neck squamous cell carcinoma (HNS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd816c69c1bc0375dc49c27511e760d2
https://doi.org/10.21203/rs.3.rs-2282364/v1
https://doi.org/10.21203/rs.3.rs-2282364/v1
Publikováno v:
Cancer immunology, immunotherapy : CII.
The NLRP3 inflammasome plays cell- and tissue-specific roles in cancer, meaning that its activation in different tumors or cells may play different roles in tumor progression. We have previously described the tumor-promoting function of tumor-intrins
Autor:
Su-Wen Zhu, Mengjie Ye, Xianbin Ma, Zhi-Zhong Wu, Shu-Cheng Wan, Shao-Chen Yang, Hao Li, Zhigang Xu, Zhi-Jun Sun
Publikováno v:
Acta biomaterialia. 154
As the prominent feature of the development and progression of head and neck squamous cell carcinoma (HNSCC) is immunosuppression, therapeutic strategies to restore antitumor immunity have shown promising prospects. The efficacy of chemotherapy, a ma
Autor:
Yao Xiao, Liang Mao, Qi-Chao Yang, Shuo Wang, Zhi-Zhong Wu, Shu-Cheng Wan, Meng-Jie Zhang, Zhi-Jun Sun
Publikováno v:
Oral Oncology. 138:106331
Publikováno v:
Oral Diseases. 28:364-372
Receptor for hyaluronic acid (HA)-mediated motility (RHAMM) is also known as CD168. This study proposed to elucidate the prognostic and clinicopathological significance of CD168 expression in oral squamous cell carcinoma (OSCC).Immune staining of a h
Autor:
Cong-Cong Wu, Yao Xiao, Lei-Lei Yang, Hao Wu, Zhi-Jun Sun, Hao Li, Wen-Feng Zhang, Shu-Cheng Wan, Wei-Wei Deng
Publikováno v:
Journal of Molecular Histology. 51:531-540
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger (P-Rex) proteins control many fundamental cellular functions including cell migration, actin cytoskeletal rearrangement and adhesion in many cancers. However, P-Rex1 expression and its