Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Shu Uin Gan"'
Autor:
Jiayi Liu, Bowen Sun, Wenkai Li, Han-Joon Kim, Shu Uin Gan, John S. Ho, Juwita Norasmara Bte Rahmat, Yong Zhang
Publikováno v:
Light: Science & Applications, Vol 13, Iss 1, Pp 1-15 (2024)
Abstract Using photodynamic therapy (PDT) to treat deep-seated cancers is limited due to inefficient delivery of photosensitizers and low tissue penetration of light. Polymeric nanocarriers are widely used for photosensitizer delivery, while the self
Externí odkaz:
https://doaj.org/article/25cb4066bc734e31b4ac0842f2e62eb5
Autor:
Subramanian Arjunan, Shu Uin Gan, Mahesh Choolani, Vaishnevi Raj, Jane Lim, Arijit Biswas, Ariff Bongso, Chui Yee Fong
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Keloid formation occurs in Caucasian, African, and Asian populations and is a severe psychosocial burden on patients. There is no permanent treatment for this problem as its pathogenesis is not properly understood. Furthermore, di
Externí odkaz:
https://doaj.org/article/40e0e98dea854e42b1f588335765c4ff
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The potent costimulatory effect of CD137 has been implicated in several murine autoimmune disease models. CD137 costimulates and polarizes antigen-specific T cells toward a potent Th1/Tc1 response, and is essential for the development of experimental
Externí odkaz:
https://doaj.org/article/bf106b120ff146718c73bbef7ecf1d7f
Publikováno v:
Stem Cell Research, Vol 47, Iss , Pp 101880- (2020)
Gestational diabetes mellitus (GDM) has been strongly associated with an increased risk of type 2 diabetes mellitus (T2DM) in later child and adulthood. The human umbilical cord and its contents are of fetal origin and represent the fetus genetically
Externí odkaz:
https://doaj.org/article/f5bccb45683c4385b66c1d14d0a4da00
Publikováno v:
Cells, Vol 9, Iss 11, p 2474 (2020)
We have previously used a hepatotropic adeno-associated viral (AAV) vector with a modified human insulin gene to treat diabetic mice. The HLP (hybrid liver-specific promoter) used was constitutively active and non-responsive to glucose. In this study
Externí odkaz:
https://doaj.org/article/36140b25fe8f4692a27038cb298e2d6a
Autor:
Hai Van Thi Do, Wan Ting Loke, Irene Kee, Vivienne Liang, Sebastian J. David, Shu Uin Gan, Sze Sing Lee, Wai Har Ng, Heng Nung Koong, Hock Soo Ong, Kok Onn Lee, Roy Y. Calne, Oi Lian Kon
Publikováno v:
Cell Transplantation, Vol 24 (2015)
Cell therapy could potentially meet the need for pancreas and islet transplantations in diabetes mellitus that far exceeds the number of available donors. Bone marrow stromal cells are widely used in clinical trials mainly for their immunomodulatory
Externí odkaz:
https://doaj.org/article/5ef5ae364afe41328072145fab7fe44d
Autor:
Heming Wei, Guangqin Zhang, Suhua Qiu, Jun Lu, Jingwei Sheng, Manasi, Grace Tan, Philip Wong, Shu Uin Gan, Winston Shim
Publikováno v:
PLoS ONE, Vol 8, Iss 9 (2013)
Externí odkaz:
https://doaj.org/article/67b2985eb6f04af59041eb6e40389c73
Autor:
Heming Wei, Guangqin Zhang, Suhua Qiu, Jun Lu, Jingwei Sheng, Manasi, Grace Tan, Philip Wong, Shu Uin Gan, Winston Shim
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50641 (2012)
AimHydrogen sulfide (H₂S) is a promising cardioprotective agent and a potential modulator of cardiac ion currents. Yet its cardiac effects on humans are poorly understood due to lack of functional cardiomyocytes. This study investigates electrophys
Externí odkaz:
https://doaj.org/article/b9311f0a0dfb44ec80e032ac26ee02d0
Autor:
Yue Zhou, Shu Uin Gan, Gen Lin, Yan Ting Lim, Jeyakumar Masilamani, Fatimah Bte Mustafa, Meow Ling Phua, Laura Rivino, Toan Thang Phan, Kok Onn Lee, Roy Calne, Paul A. Macary
Publikováno v:
Cell Transplantation, Vol 20 (2011)
In this study we describe the derivation and immunological characterization of a primary epithelial cell type from the human umbilical cord membrane. These cord lining epithelial cells (CLECs) expressed and/or secreted isoforms of the nonclassical hu
Externí odkaz:
https://doaj.org/article/72d8a900ec5c44b19e13a2e558c64299
Autor:
Hwee Hui Lau, Adrian Kee Keong Teo, Heiko Lickert, Shu Uin Gan, Kok Onn Lee, A. M. J. Shapiro
Publikováno v:
Med. 2:1138-1162
Summary The discovery of insulin a century ago changed the lives of millions of individuals suffering from diabetes, paving the way for long-term survival. While the availability of recombinant insulin for hormone replacement therapy has served extre