Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shu Shyan Wong"'
Autor:
Ludmila V. Roze, Maris Laivenieks, Sung-Yong Hong, Josephine Wee, Shu-Shyan Wong, Benjamin Vanos, Deena Awad, Kenneth C. Ehrlich, John E. Linz
Publikováno v:
Toxins, Vol 7, Iss 5, Pp 1411-1430 (2015)
Aflatoxin biosynthesis in the filamentous fungus Aspergillus parasiticus involves a minimum of 21 enzymes, encoded by genes located in a 70 kb gene cluster. For aflatoxin biosynthesis to be completed, the required enzymes must be transported to speci
Externí odkaz:
https://doaj.org/article/abb9abf9b74349e69ac81fb46e4d5d88
Autor:
J. Helen Leonard, Xuan L. Yong, Stephen A. Ainger, Dubravka Skalamera, Shu Shyan Wong, Brian Gabrielli, Richard A. Sturm
Publikováno v:
Experimental Dermatology. 23:916-921
Dopachrome tautomerase (DCT) is involved in the formation of the photoprotective skin pigment eumelanin and has also been shown to have a role in response to apoptotic stimuli and oxidative stress. The effect of DCT on UVR DNA damage responses and su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea34f0837263e0c11ad69149f282c048
https://doi.org/10.1111/exd.12574
https://doi.org/10.1111/exd.12574
Publikováno v:
Journal of Investigative Dermatology. 132:1452-1461
Variant alleles of the human melanocortin 1 receptor (MC1R) reduce the ability of melanocytes to produce the dark pigment eumelanin, with R alleles being most deficient. Cultured melanocytes of MC1R R/R variant genotype give reduced responses to [Nle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e2851192bcbea4352b9da274007bda
https://doi.org/10.1038/jid.2011.473
https://doi.org/10.1038/jid.2011.473
Autor:
Glenn L. Millhauser, Kimberley A. Beaumont, Shu Shyan Wong, Mira Patel, Richard A. Sturm, Jennifer J. Smith, Yan Yan Liu, Paul F. Alewood, Stephen A. Ainger, J. Helen Leonard
Publikováno v:
European Journal of Pharmacology. 660:103-110
The melanocortin MC(1) receptor is a G-protein coupled receptor expressed in the melanocytes of the skin and hair and is known for its key role in the regulation of human pigmentation. Melanocortin MC(1) receptor activation after ultraviolet radiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b525de6d23f4f8308131a81a59588b73
https://doi.org/10.1016/j.ejphar.2010.11.040
https://doi.org/10.1016/j.ejphar.2010.11.040
Publikováno v:
Experimental Dermatology. 20:681-684
A co-culture system of melanocytic cells and keratinocytes was used to examine dendricity and dopachrome tautomerase (DCT) responses in low penetrant 'r' homozygote and 'R/+' heterozygote MC1R variant allele expressing cells compared to that of wild-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f5ec26297c6ec1a9fe9e8f9c2c6dea
https://doi.org/10.1111/j.1600-0625.2011.01293.x
https://doi.org/10.1111/j.1600-0625.2011.01293.x
Autor:
Deena Awad, Shu Shyan Wong, Ludmila V. Roze, Maris Laivenieks, Sung Yong Hong, Josephine Wee, John E. Linz, Kenneth C. Ehrlich, Benjamin Vanos
Publikováno v:
Toxins
Volume 7
Issue 5
Pages 1411-1430
Toxins, Vol 7, Iss 5, Pp 1411-1430 (2015)
Volume 7
Issue 5
Pages 1411-1430
Toxins, Vol 7, Iss 5, Pp 1411-1430 (2015)
Aflatoxin biosynthesis in the filamentous fungus Aspergillus parasiticus involves a minimum of 21 enzymes, encoded by genes located in a 70 kb gene cluster. For aflatoxin biosynthesis to be completed, the required enzymes must be transported to speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7d86f1a726777190ca84a0fe0c7e66
https://pubmed.ncbi.nlm.nih.gov/25928133
https://pubmed.ncbi.nlm.nih.gov/25928133
Publikováno v:
Toxicology. 114:67-79
The effects of the mycotoxin cyclopiazonic acid (CPA) on cytokine secretion and gene expression were evaluated in the WEHI-3 murine macrophage cell line. Lipopolysaccharide (LPS)-stimulated and non-stimulated cells were exposed to various concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8219b3562d007c1500936d00c24758
https://doi.org/10.1016/s0300-483x(96)03416-6
https://doi.org/10.1016/s0300-483x(96)03416-6
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 857(2)
This report describes a procedure for purification of large conductance calcium-activated potassium (BK, maxi-K) channels using immobilised metal affinity chromatography (IMAC) under non-denaturing conditions. An amino-terminal histidine fusion tag w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49d6e52bbf1e4804ed3ddfd9cbf1782
https://pubmed.ncbi.nlm.nih.gov/17706472
https://pubmed.ncbi.nlm.nih.gov/17706472
Publikováno v:
Journal of toxicology and environmental health. Part A. 65(16)
The effects of vomitoxin (VT) on the binding activity of three transcription factors critical to pro-inflammatory cytokine regulation were assessed in the RAW 264.7 murine macrophage model by electrophoretic mobility shift assay (EMSA). When cells we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04abd810cd947e8a5b241a1569c4d910
https://pubmed.ncbi.nlm.nih.gov/12167214
https://pubmed.ncbi.nlm.nih.gov/12167214
Publikováno v:
Toxicology. 161(1-2)
Vomitoxin (VT or deoxynivalenol), a trichothecene, superinduces proinflammatory cytokine gene expression in vitro and in vivo. To better understand the underlying molecular mechanisms for this observation, post-transcriptional effects of VT on TNF-al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2750bd6d1b9edd55a8a4410361e7bae9
https://pubmed.ncbi.nlm.nih.gov/11295263
https://pubmed.ncbi.nlm.nih.gov/11295263