Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Shu Kuei Huang"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 3, Pp 168-175 (2017)
Decreased brain glutamate level has emerged as a new therapeutic approach for epilepsy. This study investigated the effect and mechanism of amiodarone, an anti-arrhythmic drug with antiepileptic activity, on glutamate release in the rat hippocampus.
Externí odkaz:
https://doaj.org/article/42085108127a4c03ba46fb811b1c5c1c
Autor:
Cheng-Wei Lu, Jih-Hsin Huang, Kuan-Ming Chiu, Shu Kuei Huang, Tzu-Yu Lin, Su-Jane Wang, Ming-Yi Lee
Publikováno v:
Canadian Journal of Physiology and Pharmacology. :1-7
Oxycodone, a semisynthetic opioid analgesic with actions similar to morphine, is extensively prescribed for treatment of moderate to severe acute pain. Given that glutamate plays a crucial role in mediating pain transmission, the purpose of this stud
Publikováno v:
Chemical Research in Toxicology. 32:1591-1598
The effect of cycloheterophyllin, a prenylflavone isolated from Artocarpus heteophyllus, on glutamate release was studied in the rat hippocampus using synaptosome and slice preparations. In rat hippocampal synaptosomes, cycloheterophyllin inhibited 4
Publikováno v:
Korean Journal of Physiology & Pharmacology. 2018, Vol. 22 Issue 3, p249-255. 7p.
Publikováno v:
CNSneurological disorders drug targets. 21(4)
Background: Regulation of glutamate release is crucial for maintaining normal brain function, but excess glutamate release is implicated in many neuropathological conditions. Therefore, the minimum glutamate release from presynaptic nerve terminals i
Autor:
Shu-Kuei Huang, Mei-Hwa Chih
Publikováno v:
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine. 15(10)
Background: Breastfeeding is an important health concern for postpartum women. Objective: This study aimed to investigate the effect of breastfeeding frequency on the level of serum prolactin (PRL)...
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:1685-1693
Echinacoside is a major compound of Cistanche Herb and has glutamate release-inhibiting activity in the brain. Given the involvement of excitotoxicity caused by massive glutamate in the pathophysiology of epilepsy, we explored the antiepileptic effec
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 86:122-130
CGS12066, a 5-hydroxytryptamine 1B (5-HT1B) receptor agonist, has been reported to exhibit antidepressant activity. Considering that glutamatergic dysfunction is implicated in depression, the effect of CGS12066 on glutamate release in rat hippocampal
Publikováno v:
Neurochemistry International. 116:85-94
Excitotoxic damage caused by increased glutamate levels is involved in the pathogenesis of neurodegenerative diseases. Astaxanthin, a natural carotenoid with multiple health benefits, inhibits glutamate release from the brain tissue; however, whether
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 96:479-484
Lycopene is a natural dietary carotenoid that was reported to exhibit a neuroprotective profile. Considering that excitotoxicity and cell death induced by glutamate are involved in many brain disorders, the effect of lycopene on glutamate release in