Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Shu Kuei Huang"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 3, Pp 168-175 (2017)
Decreased brain glutamate level has emerged as a new therapeutic approach for epilepsy. This study investigated the effect and mechanism of amiodarone, an anti-arrhythmic drug with antiepileptic activity, on glutamate release in the rat hippocampus.
Externí odkaz:
https://doaj.org/article/42085108127a4c03ba46fb811b1c5c1c
Autor:
Cheng-Wei Lu, Jih-Hsin Huang, Kuan-Ming Chiu, Shu Kuei Huang, Tzu-Yu Lin, Su-Jane Wang, Ming-Yi Lee
Publikováno v:
Canadian Journal of Physiology and Pharmacology. :1-7
Oxycodone, a semisynthetic opioid analgesic with actions similar to morphine, is extensively prescribed for treatment of moderate to severe acute pain. Given that glutamate plays a crucial role in mediating pain transmission, the purpose of this stud
Publikováno v:
Chemical Research in Toxicology. 32:1591-1598
The effect of cycloheterophyllin, a prenylflavone isolated from Artocarpus heteophyllus, on glutamate release was studied in the rat hippocampus using synaptosome and slice preparations. In rat hippocampal synaptosomes, cycloheterophyllin inhibited 4
Publikováno v:
Korean Journal of Physiology & Pharmacology. 2018, Vol. 22 Issue 3, p249-255. 7p.
Publikováno v:
CNSneurological disorders drug targets. 21(4)
Background: Regulation of glutamate release is crucial for maintaining normal brain function, but excess glutamate release is implicated in many neuropathological conditions. Therefore, the minimum glutamate release from presynaptic nerve terminals i
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67215 (2013)
Berberine, an isoquinoline plant alkaloid, protects neurons against neurotoxicity. An excessive release of glutamate is considered to be one of the molecular mechanisms of neuronal damage in several neurological diseases. In this study, we investigat
Externí odkaz:
https://doaj.org/article/8584b1b6d91b4dc59eb0f5ae63e52b48
Autor:
Shu-Kuei Huang, Mei-Hwa Chih
Publikováno v:
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine. 15(10)
Background: Breastfeeding is an important health concern for postpartum women. Objective: This study aimed to investigate the effect of breastfeeding frequency on the level of serum prolactin (PRL)...
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:1685-1693
Echinacoside is a major compound of Cistanche Herb and has glutamate release-inhibiting activity in the brain. Given the involvement of excitotoxicity caused by massive glutamate in the pathophysiology of epilepsy, we explored the antiepileptic effec
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 86:122-130
CGS12066, a 5-hydroxytryptamine 1B (5-HT1B) receptor agonist, has been reported to exhibit antidepressant activity. Considering that glutamatergic dysfunction is implicated in depression, the effect of CGS12066 on glutamate release in rat hippocampal
Publikováno v:
Neurochemistry International. 116:85-94
Excitotoxic damage caused by increased glutamate levels is involved in the pathogenesis of neurodegenerative diseases. Astaxanthin, a natural carotenoid with multiple health benefits, inhibits glutamate release from the brain tissue; however, whether