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Gut microbiota dysbiosis contributes to α-synuclein-related pathology associated with C/EBPβ/AEP signaling activation in a mouse model of Parkinson's disease

Autor: Xiaoli Fang, Sha Liu, Bilal Muhammad, Mingxuan Zheng, Xing Ge, Yan Xu, Shu Kan, Yang Zhang, Yinghua Yu, Kuiyang Zheng, Deqin Geng, Chun-Feng Liu

Publikováno v: Neural Regeneration Research, Vol 19, Iss 9, Pp 2081-2088 (2024)

[INLINE:1] Parkinson's disease is a neurodegenerative disease characterized by motor and gastrointestinal dysfunction. Gastrointestinal dysfunction can precede the onset of motor symptoms by several years. Gut microbiota dysbiosis is involved in the

Externí odkaz: https://doaj.org/article/e872b3aea1524cb18f3ff2e27814f535

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Akademický článek

Elevated NT-proBNP predicts unfavorable outcomes in patients with acute ischemic stroke after thrombolytic therapy

Autor: Zhuang Zhu, Bilal Muhammad, Bo Du, Ning Gu, Tian-Yue Meng, Shu Kan, Ying-Feng Mu, Yan-Bo Cheng, Shi-Guang Zhu, De-Qin Geng

Publikováno v: BMC Neurology, Vol 23, Iss 1, Pp 1-10 (2023)

Abstract Objective Few studies correlated n-terminal pro-brain natriuretic peptide (NT-proBNP) with early neurological deterioration (END) and prognosis of acute ischaemic stroke (AIS) patients with rt-PA intravenous thrombolysis. Therefore this stud

Externí odkaz: https://doaj.org/article/acda95c52f70448d918b87b6cefd799f

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Akademický článek

Cryptotanshinone against vascular dementia through inhibition of Aβ aggregation and inflammatory responses in cerebrovascular endothelial cells

Autor: Hongmei Ding, Shu Kan, Xiaolong Wang, Bo Du, Yingfeng Mou, Ruiguo Dong, Deqin Geng, Qichen Pang

Publikováno v: Arabian Journal of Chemistry, Vol 15, Iss 12, Pp 104328- (2022)

Abnormal aggregation of amyloid-β (Aβ) peptides and associated inflammation and apoptosis in cerebrovascular endothelial cells are prelude to inhibition of onset of vascular dementia (VaD). Although small molecules have been widely used to mitigate

Externí odkaz: https://doaj.org/article/2893fea050a84592ac6eefb358dab14d

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Akademický článek

Feasibility of Using High-Contrast Grating as a Point-of-Care Sensor for Therapeutic Drug Monitoring of Immunosuppressants

Autor: Yi-Cheng Liu, Christina Thantrakul, Shu Kan, Connie Chang-Hasnain, Dong-Ru Ho

Publikováno v: IEEE Journal of Translational Engineering in Health and Medicine, Vol 8, Pp 1-6 (2020)

Point-of-care (POC) testing has demonstrated great transformative potential in personalized medicine. In particular, patients undergoing transplantation require POC testing to ensure appropriate serum immunosuppressant levels so as to maintain adequa

Externí odkaz: https://doaj.org/article/89135f594cbd4014be737f4556afb948

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Akademický článek

Quantum computing quantum Monte Carlo with hybrid tensor network for electronic structure calculations

Autor: Shu Kanno, Hajime Nakamura, Takao Kobayashi, Shigeki Gocho, Miho Hatanaka, Naoki Yamamoto, Qi Gao

Publikováno v: npj Quantum Information, Vol 10, Iss 1, Pp 1-13 (2024)

Abstract Quantum computers have a potential for solving quantum chemistry problems with higher accuracy than classical computers. Quantum computing quantum Monte Carlo (QC-QMC) is a QMC with a trial state prepared in quantum circuit, which is employe

Externí odkaz: https://doaj.org/article/e5c619d814bd41ef974150ef09e43923

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Neutrophil-to-lymphocyte Ratio as a Risk Determinant of Hemorrhage Transformation in Acute Ischemic Stroke

Autor: Bilal Muhammad, Chen Xi, Ying-Feng Mu, Zi-Peng Wang, Deqin Geng, Zhen-Ying Shang, Wei Wang, Wang Li, Jin-Feng Lv, Shuang Ma, Shu Kan

Publikováno v: Journal of Modern Neurology. :8-16

Objective: The purpose of this study was to investigate the clinical significance between neutrophil-to-lymphocyte ratio (NLR) and classification of non-thrombolytic hemorrhagic transformation (HT) in acute ischemic stroke (AIS), to unravel new diagn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e2b4efc9f05d4580187b41184c62cb8
https://doi.org/10.36922/jmn.v5i1.900

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Akademický článek

Exposure to Radon Progeny, Tobacco Use and Lung Cancer in a Case-Control Study in Southern China

Autor: Yao, Shu Xiang, Lubin, Jay H., Qiao, You Lin, Boice,, John D., Li, Jun Yao, Cai, Shu Kan, Zhang, Fu Ming, Blot, William J.

Publikováno v: Radiation Research, 1994 Jun 01. 138(3), 326-336.

Externí odkaz: https://www.jstor.org/stable/3578680

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Intrinsic impacts of the expression of PD-L1 on postoperative recurrence in EGFR-mutated lung adenocarcinoma

Autor: Atsushi Ito, Shu Kano, Tomohito Tarukawa, Yuta Suzuki, Tadashi Sakaguchi, Kentaro Ito, Yoichi Nishii, Osamu Taguchi, Hiroki Yasui, Motoshi Takao, Osamu Hataji

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

ObjectivesThis study aimed to assess the intrinsic impacts of the expression of PD-L1 on postoperative recurrence and the prognosis in patients with epidermal growth factor receptor (EGFR)-mutated lung adenocarcinomas.Patients and methodsData from 22

Externí odkaz: https://doaj.org/article/c0e0b61e81f84ee6a9005026c1576afa

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Akademický článek

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Feasibility of Using High-Contrast Grating as a Point-of-Care Sensor for Therapeutic Drug Monitoring of Immunosuppressants

Autor: Dong-Ru Ho, Connie J. Chang-Hasnain, Yi-Cheng Liu, Shu Kan, Christina Thantrakul

Publikováno v: IEEE Journal of Translational Engineering in Health and Medicine
IEEE Journal of Translational Engineering in Health and Medicine, Vol 8, Pp 1-6 (2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bfe84b5fc16d8d3b45750c0df43e5e
https://escholarship.org/uc/item/21g8d1rw

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