Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Shu Han Chao"'
Publikováno v:
Biochemistry. 56:5671-5678
PEGylated proteins play an increasingly important role in pharmaceutical drug delivery. We recently showed that short poly(ethylene glycol) (PEG) chains can affect protein structure, even when they are not making extensive contact with the protein su
Autor:
Maxim Belkin, Cees Dekker, Sergii Pud, Casper Van Engelenburg, Teun A.P.M. Huijben, Aleksei Aksimentiev, Daniel Verschueren, Shu Han Chao
Publikováno v:
Nano Letters
Nanopores have become ubiquitous components of systems for single-molecule manipulation and detection, in particular DNA sequencing where electric field-driven translocation of DNA through a nanopore is used to read out the DNA molecule. Here, we pre
Publikováno v:
Biochemistry. 56(42)
PEGylated proteins play an increasingly important role in pharmaceutical drug delivery. We recently showed that short PEG chains can affect protein structure, even when they are not making extensive contact with the protein surface. In contrast, PEG
Autor:
Yu-Ju Tsai, Shu Han Chao, Hsien-Ming Lee, Joseph Jen-Tse Huang, Chu Yi Yu, Ruei Yu He, Yung An Huang, Eric Hwang, Hua De Gao, Chi Chang Lee
Publikováno v:
ACS nano. 11(7)
The abnormal assembly of misfolded proteins into neurotoxic aggregates is the hallmark associated with neurodegenerative diseases. Herein, we establish a photocontrollable platform to trigger amyloidogenesis to recapitulate the pathogenesis of amyotr
Autor:
Aleksei Aksimentiev, Shu Han Chao, Martin Gruebele, Ryan J Paxman, Joshua L. Price, Sam S. Matthews
Publikováno v:
The Journal of Physical Chemistry B. 118:8388-8395
PEGylation, or addition of poly(ethylene glycol) chains to proteins, is widely used to improve delivery in pharmaceutical applications. Recent studies suggest that stabilization of a protein by PEG, and hence its proteolytic degradability, is sequenc
Publikováno v:
The Journal of Physical Chemistry. B
Wild type apomyoglobin folds in at least two steps: the ABGH core rapidly, followed much later by the heme-binding CDEF core. We hypothesize that the evolved heme-binding function of the CDEF core frustrates its folding: it has a smaller contact orde
Publikováno v:
Total Quality Management & Business Excellence. 22:305-329
A virtual team is a network group where team members from different cultures are temporarily gathered together for the period of a mission. The present research proposes a general model of virtual teams to investigate how cultural adaptation, communi
Publikováno v:
Journal of Crystal Growth. 311:4381-4384
We report a simple fabrication process for the growth of nanotip-decorated ZnO nanobottles with an enhanced field emission property. Well-aligned ZnO nanobottles grown on ITO-coated glass substrates were synthesized by the thermal evaporation techniq
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(26)
Fast protein folding involves complex dynamics in many degrees of freedom, yet microsecond folding experiments provide only low-resolution structural information. We enhance the structural resolution of the five-helix bundle protein λ6–85 by engin
Autor:
Shu-Han Chao, 趙書含
103
The issue of same-sex relationships has been an important topic of debate under international and national law. By taking a socio-legal perspective, this thesis investigates the historical background and the evolution of law regarding same-s
The issue of same-sex relationships has been an important topic of debate under international and national law. By taking a socio-legal perspective, this thesis investigates the historical background and the evolution of law regarding same-s
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/13871742753041264622