Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Shu Fei Lin"'
Autor:
Yiyun Huang, Shannan Henry, Nabeel Nabulsi, Izumi Nishino, David Labaree, Satoshi Ozaki, Ming-Rong Zhang, Tetsuya Suhara, Mika Naganawa, Hong Gao, Richard Pracitto, Shu-fei Lin, David Matuskey, Jim Ropchan, Helene D. Sabia, Richard E. Carson
Publikováno v:
Journal of Nuclear Medicine. 63:609-614
Arginine vasopressin (AVP) is a hormone that is mainly synthesized in the hypothalamus and stored in the posterior pituitary. Receptors for vasopressin are categorized into at least three subtypes (V1A, V1B, V2). Among these subtypes, the V1B recepto
Autor:
Naganawa, Mika, B. Nabulsi, Nabeel, Matuskey, David, Henry, Shannan, Ropchan, Jim, Shu-Fei, Lin, Gao, Hong, Pracitto, Richard, Labaree, David, Zhang, Ming-Rong, Tetsuya, Suhara, Nishino, Izumi, Sabia, Helene, Ozaki, Satoshi, Huang, Yiyun, E. Carson, Richar
Publikováno v:
Journal of Nuclear Medicine. 63(4):609-614
Arginine vasopressin (AVP) is a hormone that is mainly synthesized in the hypothalamus and stored in the posterior pituitary. Receptors for vasopressin are categorized into at least three subtypes (V1A, V1B, V2). Among these subtypes, the V1B recepto
Autor:
Shu-fei Lin PhD, Frederic Bois PhD, Daniel Holden BA, Nabeel Nabulsi PhD, Richard Pracitto MS, Hong Gao MS, Michael Kapinos BS, Jo-ku Teng BS, Anupama Shirali PhD, Jim Ropchan PhD, Richard E. Carson PhD, Charles S. Elmore PhD, Neil Vasdev PhD, Yiyun Huang PhD
Publikováno v:
Molecular Imaging, Vol 16 (2017)
The myriad physiological functions of γ-amino butyric acid (GABA) are mediated by the GABA-benzodiazepine receptor complex comprising of the GABA A , GABA B , and GABA C groups. The various GABA A subunits with region-specific distributions in the b
Externí odkaz:
https://doaj.org/article/497bac56eec240b688692fea73023b35
Autor:
Rajiv Radhakrishnan, Nabeel Nabulsi, Edward Gaiser, Jean-Dominique Gallezot, Shannan Henry, Beata Planeta, Shu-fei Lin, Jim Ropchan, Wendol Williams, Evan Morris, Deepak Cyril D’Souza, Yiyun Huang, Richard E. Carson, David Matuskey
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 3-4 (2018)
OBJECTIVES/SPECIFIC AIMS: The serotonin receptor 6 (5-HT6) is a potential therapeutic target given its distribution in brain regions that are important in depression, anxiety, and cognition. This study sought to investigate the effects of age on 5-HT
Externí odkaz:
https://doaj.org/article/9b7f331f23664c908f1e521eae84abf8
Autor:
Jayanta Mondal, Nabeel Nabulsi, Yiyun Huang, Jean-Dominique Gallezot, Mika Naganawa, Sjoerd J. Finnema, Hannah R. Michalak, Ming-Kai Chen, Brent C. Vander Wyk, Richard E. Carson, Takuya Toyonaga, Shu-fei Lin, Ryan S. O'Dell, Christopher H. van Dyck, Julia W. McDonald, Amy F.T. Arnsten, Adam P. Mecca
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 41:2395-2409
[11C]UCB-J PET for synaptic vesicle glycoprotein 2 A (SV2A) has been proposed as a suitable marker for synaptic density in Alzheimer’s disease (AD). We compared [11C]UCB-J binding for synaptic density and [18F]FDG uptake for metabolism (correlated
Autor:
Yihuan Lu, Mark Dias, Nabeel Nabulsi, Richard E. Carson, Yiyun Huang, Qianyu Wang, Dennis D. Spencer, Ming-Kai Chen, Jean-Dominique Gallezot, Sjoerd J. Finnema, Mika Naganawa, Shu-fei Lin, Takuya Toyonaga, Kamil Detyniecki
Publikováno v:
Epilepsia. 61:2183-2193
OBJECTIVE In this positron emission tomography (PET) study with [11 C]UCB-J, we evaluated synaptic vesicle glycoprotein 2A (SV2A) binding, which is decreased in resected brain tissues from epilepsy patients, in subjects with temporal lobe epilepsy (T
First-in-Human Assessment of 11C-LSN3172176, an M1 Muscarinic Acetylcholine Receptor PET Radiotracer
Autor:
David Labaree, Nabeel Nabulsi, Kevin Michael Ruley, Antonio Navarro, David Matuskey, Jim Ropchan, Adam J. Schwarz, Hong Gao, Nancy Kant, Shu-fei Lin, Cynthia Darshini Jesudason, Richard E. Carson, Mika Naganawa, Lawrence J. Slieker, Shannan Henry, Yiyun Huang
Publikováno v:
Journal of Nuclear Medicine. 62:553-560
This was a first-in-human study of the PET radiotracer 11C-LSN3172176 for the muscarinic acetylcholine receptor subtype M1. The objectives of the study were to determine the appropriate kinetic model to quantify binding of the tracer to M1 receptors,
Autor:
Ming-Qiang Zheng, Richard E. Carson, Marcel Lindemann, Zhengxin Cai, Chi Liu, Hui Liu, Michael Kapinos, Wenjie Zhang, Shu-fei Lin, Jo-ku Teng, Nabil E. Boutagy, Tim Mulnix, Attila Feher, John C. Stendahl, Edward J. Miller, Jing Wu, Albert J. Sinusas, Yiyun Huang, Jean-Dominique Gallezot
Publikováno v:
Journal of Nuclear Cardiology. 29:216-225
We aimed to develop a dynamic imaging technique for a novel PET superoxide tracer, [18F]DHMT, to allow for absolute quantification of myocardial reactive oxygen species (ROS) production in a large animal model. Six beagle dogs underwent a single base
Autor:
Hongmei Jia, Yingfang He, Shu-fei Lin, Jim Ropchan, Anupama Shirali, Evan Baum, Yiyun Huang, Michael Kapinos, Zhengxin Cai, Hong Gao, Daniel Holden, Songye Li
Publikováno v:
ACS Chemical Neuroscience. 11:1673-1681
We report a convenient radiosynthesis and the first positron emission tomography (PET) imaging evaluation of [18F]FBFP as a potent sigma-1 (σ1) receptor radioligand with advantageous characteristics. [18F]FBFP was synthesized in one step from an iod
Autor:
Nabeel Nabulsi, Yiyun Huang, David Labaree, Michael Mei, Songye Li, Shannan Henry, Shu-fei Lin, David Matuskey, Mika Naganawa, Hong Gao, Jim Ropchan, Richard E. Carson
Publikováno v:
Journal of Nuclear Medicine. 61:1636-1642
The kappa opioid receptor (KOR) is implicated in various neuropsychiatric disorders. We previously evaluated an agonist tracer, 11C-GR103545, for PET imaging of KOR in humans. Although 11C-GR103545 showed high brain uptake, good binding specificity,