Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shu Fang Jia"'
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 37, Iss 12, Pp 1115-1119 (2012)
Objective To prepare a novel biomimetic agent with adhesive and osteoinduction capabilities, and provide a new approach for improving seeding cell adhesion and osteoblastic differentiation on a scaffold surface. Methods A novel bifunctional recombina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::4e0305ffdcdf5917674f728bc01d04cd
http://www.plamj.org/index.php/plamj/article/view/608
http://www.plamj.org/index.php/plamj/article/view/608
Autor:
Zhichao Zhou, Tim H. Lee, Ying Cao, Krishna Reddy, Shu Fang Jia, Eugenie S. Kleinerman, Jaime Morales-Arias
Publikováno v:
International Journal of Cancer. 123:831-837
Stromal cell-derived Factor-1alpha (SDF-1alpha) stimulates the migration of bone marrow (BM) cells, similar to vascular endothelial growth factor (VEGF). We previously demonstrated that inhibition of VEGF(165) by small interfering RNA inhibited Ewing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4596ad79263f909cd848a025b1f7a55
https://doi.org/10.1002/ijc.23582
https://doi.org/10.1002/ijc.23582
Publikováno v:
Cancer Gene Therapy. 13:948-957
We evaluated the effect of interleukin-12 (IL-12) gene therapy using an Ewing's sarcoma animal model in T-cell-deficient nude mice. Subcutaneous injection of TC71 cells resulted in tumor development by day 5. Mice were treated with a single intratumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebe4e8d2e01cb548fa7f9bdf7de075c
https://doi.org/10.1038/sj.cgt.7700968
https://doi.org/10.1038/sj.cgt.7700968
Publikováno v:
Cancer. 106:1382-1388
BACKGROUND Cyclophosphamide (CTX) and ifosfamide (IFX) are alkylating agents used to treat osteosarcoma (OS). It was previously demonstrated that the sensitivity of OS cells to 4-hydroperoxycyclophosphamide (4-HC, the active metabolite of CTX) is aug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56e2a52e6d57c1061b302ad390a74442
https://doi.org/10.1002/cncr.21744
https://doi.org/10.1002/cncr.21744
Publikováno v:
Clinical Cancer Research. 11:2662-2669
Angiogenesis plays an essential role in tumor growth and metastasis and is a promising therapeutic target for cancer. Vascular endothelial growth factor (VEGF) is a key regulator in vasculogenesis as well as in angiogenesis. TC71 human Ewing's sarcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a234ec825672a3ce3d12fae925b85da
https://doi.org/10.1158/1078-0432.ccr-04-1206
https://doi.org/10.1158/1078-0432.ccr-04-1206
Autor:
Nadezhda V. Koshkina, Xiaoping Duan, Elizabeth A. Lafleur, Laura L. Worth, John Stewart, Eugenie S. Kleinerman, Shu Fang Jia
Publikováno v:
Clinical Cancer Research. 10:8114-8119
Purpose: The process of metastasis requires the single tumor cell that seeds the metastatic clone to complete a complex series of steps. Identifying factors responsible for these steps is essential in developing and improving targeted therapy for met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90e50cb399fc70e5c7083b908c11079
https://doi.org/10.1158/1078-0432.ccr-04-0353
https://doi.org/10.1158/1078-0432.ccr-04-0353
Publikováno v:
Journal of Experimental Therapeutics and Oncology. 2:27-36
The recurrence of pulmonary metastases resistant to salvage chemotherapy continues to be a major problem in osteosarcoma patients. Our goal is to identify novel combinations of biologic response modifiers plus chemotherapeutic agents that can be tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a55081739f554267d9010441a424b9c0
https://doi.org/10.1046/j.1359-4117.2002.01003.x
https://doi.org/10.1046/j.1359-4117.2002.01003.x
Autor:
Laura L. Worth, Vernon Knight, Charles L. Densmore, Ajay Gautam, Yuen Kai Fung, Eugenie S. Kleinerman, J. Clifford Waldrep, Bo Xu, Anne T'ang, Shu Fang Jia
Publikováno v:
Cancer Gene Therapy. 8:619-627
Lung metastases are a frequent complication of osteosarcoma and a treatment that would reduce the severity of this complication would be of great benefit to patients. We have used a formulation consisting of polyethyleneimine (PEI) and a p53 gene adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8d6c5f48155e777227f775b6682b43
https://doi.org/10.1038/sj.cgt.7700343
https://doi.org/10.1038/sj.cgt.7700343
Publikováno v:
Journal of Interferon & Cytokine Research. 19:617-624
The purpose of these studies was to determine whether interferon-alpha (IFN-alpha) could enhance the sensitivity of human osteosarcoma cells to the cytotoxic actions of etoposide (VP-16). Cytostasis was determined using a [3H]thymidine incorporation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdedd7cb8eed2aa25cebe1089316e04
https://doi.org/10.1089/107999099313758
https://doi.org/10.1089/107999099313758
Publikováno v:
Clinical and Experimental Metastasis. 17:501-506
The purpose of these studies was to develop a metastatic osteosarcoma nude mouse model to evaluate the in vivo efficacy of new therapeutic compounds. Human SAOS-2 osteosarcoma cells (10(6) cells) were injected i.v. into nude mice. Cells isolated from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e516e6943e37dbac398ff82ed700de0e
https://doi.org/10.1023/a:1006623001465
https://doi.org/10.1023/a:1006623001465