Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Shu Chu Shiesh"'
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229610 (2020)
Extracellular vesicles (EVs) have attracted increasing attention because of their potential roles in various biological processes and medical applications. However, isolation of EVs is technically challenging mainly due to their small and heterogeneo
Externí odkaz:
https://doaj.org/article/c1c1027f3b604eebbd97a06dccc98930
Autor:
Chia-Ho Chu, Indu Sarangadharan, Abiral Regmi, Yen-Wen Chen, Chen-Pin Hsu, Wen-Hsin Chang, Geng-Yen Lee, Jen-Inn Chyi, Chih-Chen Chen, Shu-Chu Shiesh, Gwo-Bin Lee, Yu-Lin Wang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract In this study, a new type of field-effect transistor (FET)-based biosensor is demonstrated to be able to overcome the problem of severe charge-screening effect caused by high ionic strength in solution and detect proteins in physiological en
Externí odkaz:
https://doaj.org/article/6da60cdd46894422bf680ada3a777a0d
Autor:
Indu Sarangadharan, Yu-Lin Wang, Shin Li Wang, Gwo-Bin Lee, Geng Yen Lee, Tse Yu Tai, Anil Kumar Pulikkathodi, Anirban Sinha, Shu Chu Shiesh, Jen-Inn Chyi
Publikováno v:
Analytical Chemistry. 91:5953-5960
We have developed a swift and simplistic protein immunoassay using aptamer functionalized AlGaN/GaN high electron mobility transistors (HEMTs). The unique design of the sensor facilitates protein detection in a physiological salt environment overcomi
Publikováno v:
The Analyst. 144:4943-4951
In this study, an enzyme linked DNA aptamer based assay was optimized for human cardiac troponin I (cTnI) detection which is a prominent biomarker for acute myocardial infarction (AMI), on an integrated microfluidic platform. This platform allowed fo
Autor:
Wen Hsin Chang, Chen Pin Hsu, Chia Ho Chu, Abiral Regmi, Gwo-Bin Lee, Geng Yen Lee, Yu-Lin Wang, Jen-Inn Chyi, Shu Chu Shiesh, Indu Sarangadharan, Yen-Wen Chen, Chihchen Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
In this study, a new type of field-effect transistor (FET)-based biosensor is demonstrated to be able to overcome the problem of severe charge-screening effect caused by high ionic strength in solution and detect proteins in physiological environment
Autor:
Yen-Wen Chen, Chihchen Chen, Chen Pin Hsu, Shu Chu Shiesh, Indu Sarangadharan, Pei Chi Chen, Yu-Lin Wang, Gwo-Bin Lee
Publikováno v:
ECS Journal of Solid State Science and Technology. 6:Q71-Q76
Publikováno v:
Lab on a chip. 19(19)
Circulating extracellular vesicles (EVs), which can contain a wide variety of molecules such as proteins, messenger ribonucleic acids (mRNAs), micro ribonucleic acids (miRNAs) and deoxyribonucleic acids (DNAs) from cells or tissues of origin, have at
Publikováno v:
2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII).
Cardiovascular diseases (CVDs) have resulted in an estimated death toll of nearly 17 million yearly. Early detection of CVDs may reduce the risk of sudden deaths. The current technologies based on antigen-antibody interactions have limitations in poi
Publikováno v:
Lab on a chip. 19(9)
Although cardiovascular diseases such as heart failure (HF) affect 30 million people globally, the early detection of HF has, until recently, been difficult and prone to misdiagnoses. Monitoring the circulatory levels of a relatively new biomarker, t
Autor:
Tse Yu Tai, Shu Chu Shiesh, Po Chiun Huang, Gwo-Bin Lee, Anirban Sinha, Indu Sarangadharan, Hsi-Pin Ma, Kuang Hsien Li, Priya Gopinathan, Yu-Lin Wang, Yi Da Chung
Publikováno v:
Biosensorsbioelectronics. 129
Certain blood-borne biomarkers offer a potent methodology for understanding the risk of cardiovascular diseases (CVDs) with clinicians generally advocating the use of multiple biomarkers for proper risk assessment of CVDs. Herein four such CVDs bioma