Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Shu Ching Hsu"'
Autor:
Yu-Sung Chiu, Kuo-Jen Wu, Seong-Jin Yu, Kun-Lieh Wu, Yu-Syuan Wang, Jing Lin, Chia-Ying Chu, Shuchun Chen, Hsi Chen, Shu-Ching Hsu, Yun Wang, Yun-Hsiang Chen
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291927 (2023)
Abnormal accumulation of alpha-synuclein (αSyn) in the remaining nigra dopaminergic neurons is a common neuropathological feature found in patients with Parkinson's disease (PD). Antibody-based immunotherapy has been considered a potential approach
Externí odkaz:
https://doaj.org/article/5f7caeedfc2c4212b652a0008bb8fced
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Blinatumomab, a bispecific T cell engager (BiTE) antibody targeting CD19 and CD3ε, can redirect T cells toward CD19-positive tumor cells and has been approved to treat relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL). How
Externí odkaz:
https://doaj.org/article/abe8d7b431504819a9c88e7b7e55b668
Autor:
Yu-Tsen Lin, Cheng-Kai Wang, Shang-Chih Yang, Shu-Ching Hsu, Hsuan Lin, Fang-Pei Chang, Tzu-Chien Kuo, Chia-Ning Shen, Po-Ming Chiang, Michael Hsiao, Frank Leigh Lu, Jean Lu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract An important safety concern in the use of human pluripotent stem cells (hPSCs) is tumorigenic risk, because these cells can form teratomas after an in vivo injection at ectopic sites. Several thousands of undifferentiated hPSCs are sufficien
Externí odkaz:
https://doaj.org/article/542a27d04f554729a165d891f3827aa9
Autor:
Jer-Yiing Houng, Tzong-Shyuan Tai, Shu-Ching Hsu, Hsia-Fen Hsu, Tzann-Shun Hwang, Chih-Jiun Lin, Li-Wen Fang
Publikováno v:
Chinese Medicine, Vol 12, Iss 1, Pp 1-10 (2017)
Abstract Background Glossogyne tenuifolia (GT) (Hsiang-ju) is a Chinese herbal medicine previously exhibited an anti-inflammatory activity. This study aimed to investigate the effect of GT ethanol extract (GTE) on T cell-mediated adaptive immunity. M
Externí odkaz:
https://doaj.org/article/5deba7f0a1724b58ae4318e2ffa6b566
Autor:
Shu-Ching Hsu, Yu-Shao Yang, Yi-Ting Lai, Kuang-Yu Chan, Li-Cheng Lu, Chien-Hsun Huang, Chao-Ling Yao, Yung-Shiang Chan, Shih-Lung Cheng
Publikováno v:
Cytotherapy. 21:755-768
Background Dendritic cells (DCs) that are derived from hematopoietic stem cells (HSCs) are the most potent antigen-presenting cells and play a pivotal role in initiating the immune response. Hence, large-scale production and direct induction of funct
Autor:
Wei-Ju Chen, Yu-Chen Lin, Scott C. Schuyler, Wei-Kai Huang, Chun Yu Lin, Chiao-Ching Hsu, Yen-Chun Chiu, Jean Lu, Michael Hsiao, Hsuan Lin, Shang-Chih Yang, Su-Yi Tsai, Shu-Ching Hsu, Po-Wen A Tu, Yu-Tsen Lin, Chih-Lun Cheng, Frank Leigh Lu, Yi-Hsuan Lee, Jan-Jan Liu, Chien-Ying Lai, Ching-Fang Chang, Cheng-Kai Wang
Publikováno v:
FASEB J
We reveal by high-throughput screening that activating transcription factor 1 (ATF1) is a novel pluripotent regulator in human embryonic stem cells (hESCs). The knockdown of ATF1 expression significantly up-regulated neuroectoderm (NE) genes but not
Publikováno v:
Nutrients, Vol 9, Iss 11, p 1169 (2017)
Creatine supplementation reduces the impact of muscle fatigue on post-activation potentiation (PAP) of the lower body, but its effects on the upper body remain unknown. This study examined the effects of creatine supplementation on muscle strength, e
Externí odkaz:
https://doaj.org/article/b79b4e7e1a22489789780cf4422997e9
Autor:
Yih-Yuan Chen, Jia-Ru Chang, Wei-Feng Huang, Shu-Ching Hsu, Shu-Chen Kuo, Jun-Ren Sun, Horng-Yunn Dou
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94296 (2014)
It is unclear to what extent the host-responses elicited by Beijing versus non-Beijing strains of Mycobacterium tuberculosis (MTB) contribute to the predominance of modern Beijing strains in Taiwan and some other Asian countries. The purpose of this
Externí odkaz:
https://doaj.org/article/b4b5144a8a3e4c6b8fa06f2c22981995
Autor:
Kuei-Min Chung, Shu-Ching Hsu, Yue-Ru Chu, Mei-Yao Lin, Weir-Tong Jiaang, Ruey-Hwa Chen, Xin Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88772 (2014)
BACKGROUND: The ability of human bone marrow mesenchymal stem cells (BM-MSCs) to migrate and localize specifically to injured tissues is central in developing therapeutic strategies for tissue repair and regeneration. Fibroblast activation protein (F
Externí odkaz:
https://doaj.org/article/0dea8211f5234ba4babed624c9e07f72
Autor:
Mao-Liang Chen, Kuo-Jen Wu, Ho-Min Tsai, Wei Hsieh, Shuchun Chen, Seong-Jin Yu, Li-Wen Liao, Yun-Hsiang Chen, Yu-Syuan Wang, Yun Wang, Hsi Chen, Barry J. Hoffer, Shu-Ching Hsu
Publikováno v:
Journal of Parkinson's disease. 10(2)
Background Accumulation of α-synuclein (αSyn) in the dopaminergic neurons is a common pathology seen in patients with Parkinson's disease (PD). Overproduction of αSyn potentiates the formation of oligomeric αSyn aggregates and enhances dopaminerg