Zobrazeno 1 - 10
of 183
pro vyhledávání: '"Shu, Kondo"'
Autor:
Yang Gao, Ye Sing Tan, Jiaen Lin, Liang Yuh Chew, Htet Yamin Aung, Brinda Palliyana, Mahekta R. Gujar, Kun-Yang Lin, Shu Kondo, Hongyan Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract A delicate balance between neural stem cell (NSC) quiescence and proliferation is important for adult neurogenesis and homeostasis. Small ubiquitin-related modifier (SUMO)-dependent post-translational modifications cause rapid and reversible
Externí odkaz:
https://doaj.org/article/a4c01000c6014895872858c0cf7fd093
Autor:
Shunya Kaneko, Keita Miyoshi, Kotaro Tomuro, Makoto Terauchi, Ryoya Tanaka, Shu Kondo, Naoki Tani, Kei-Ichiro Ishiguro, Atsushi Toyoda, Azusa Kamikouchi, Hideki Noguchi, Shintaro Iwasaki, Kuniaki Saito
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Modification of guanosine to N7-methylguanosine (m7G) in the variable loop region of tRNA is catalyzed by the METTL1/WDR4 heterodimer and stabilizes target tRNA. Here, we reveal essential functions of Mettl1 in Drosophila fertility. Knockout
Externí odkaz:
https://doaj.org/article/4ec9e5921ce14741a2f17a3cab3b43ff
Autor:
Toshiharu Ichinose, Shu Kondo, Mai Kanno, Yuichi Shichino, Mari Mito, Shintaro Iwasaki, Hiromu Tanimoto
Publikováno v:
eLife, Vol 12 (2024)
Multicellular organisms are composed of specialized cell types with distinct proteomes. While recent advances in single-cell transcriptome analyses have revealed differential expression of mRNAs, cellular diversity in translational profiles remains u
Externí odkaz:
https://doaj.org/article/a67569df7cc14c718ffb6880427faab9
Publikováno v:
Cell Structure and Function, Vol 48, Iss 2, Pp 251-257 (2023)
Directional cell rearrangement is a critical process underlying correct tissue deformation during morphogenesis. Although the involvement of F-actin regulation in cell rearrangement has been established, the role and regulation of actin binding prote
Externí odkaz:
https://doaj.org/article/829687e4a1854daaa457c74768ac8fc7
Autor:
Justin A. Bosch, Nathan Keith, Felipe Escobedo, William W. Fisher, James Thai LaGraff, Jorden Rabasco, Kenneth H. Wan, Richard Weiszmann, Yulun Wu, Yanhui Hu, Shu Kondo, James B. Brown, Norbert Perrimon, Susan E. Celniker
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113737- (2024)
Externí odkaz:
https://doaj.org/article/9482914255e4447581d2f70f57d2085e
Autor:
Justin A. Bosch, Nathan Keith, Felipe Escobedo, William W. Fisher, James Thai LaGraff, Jorden Rabasco, Kenneth H. Wan, Richard Weiszmann, Yanhui Hu, Shu Kondo, James B. Brown, Norbert Perrimon, Susan E. Celniker
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113311- (2023)
Summary: Short polypeptides encoded by small open reading frames (smORFs) are ubiquitously found in eukaryotic genomes and are important regulators of physiology, development, and mitochondrial processes. Here, we focus on a subset of 298 smORFs that
Externí odkaz:
https://doaj.org/article/4b08ef18ffc94b6b89b291356102f40d
Autor:
Izumi Oikawa, Shu Kondo, Kao Hashimoto, Akiho Yoshida, Megumi Hamajima, Hiromu Tanimoto, Katsuo Furukubo-Tokunaga, Ken Honjo
Publikováno v:
eLife, Vol 12 (2023)
Nociception is a neural process that animals have developed to avoid potentially tissue-damaging stimuli. While nociception is triggered in the peripheral nervous system, its modulation by the central nervous system is a critical process in mammals,
Externí odkaz:
https://doaj.org/article/f5310661bcb246f8a7356547f5eb2e95
Autor:
Yuma Komori, Koichi Takayama, Naoki Okamoto, Masaki Kamiya, Wataru Koizumi, Makoto Ihara, Daitaro Misawa, Kotaro Kamiya, Yuto Yoshinari, Kazuki Seike, Shu Kondo, Hiromu Tanimoto, Ryusuke Niwa, David B. Sattelle, Kazuhiko Matsuda
Publikováno v:
PLoS Genetics, Vol 19, Iss 2 (2023)
Neonicotinoid insecticides target insect nicotinic acetylcholine receptors (nAChRs) and their adverse effects on non-target insects are of serious concern. We recently found that cofactor TMX3 enables robust functional expression of insect nAChRs in
Externí odkaz:
https://doaj.org/article/941690b3771641299e409a8ab9e03b3c
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
CCHamide-2 (CCHa2) is a protostome excitatory peptide ortholog known for various arthropod species. In fruit flies, CCHa2 plays a crucial role in the endocrine system, allowing peripheral tissue to communicate with the central nervous system to ensur
Externí odkaz:
https://doaj.org/article/84f643c7fdf74e41b0724e460dd7facd
Autor:
Yuto Yoshinari, Hina Kosakamoto, Takumi Kamiyama, Ryo Hoshino, Rena Matsuoka, Shu Kondo, Hiromu Tanimoto, Akira Nakamura, Fumiaki Obata, Ryusuke Niwa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
Incretin hormones regulate insulin and glucagon secretion in mammals, but similar peptides have not been characterized in invertebrates. Here the authors show that neuropeptide F functions similar to mammalian incretin in fruit flies, responding to s
Externí odkaz:
https://doaj.org/article/b4166c8f5f8449ef8b5ce6a3391e52f3