Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shruti S. Desai"'
Publikováno v:
International Journal of Endocrinology, Vol 2015 (2015)
Lipoma in patients with the multiple endocrine neoplasia type 1 (MEN1) syndrome is a type of benign fat-cell tumor that has biallelic inactivation of MEN1 that encodes menin and could serve as a model to investigate normal and pathologic fat-cell (ad
Externí odkaz:
https://doaj.org/article/6ee635b583854b619852e60cb2ce4b09
Autor:
Lieping Chen, Kurt A. Schalper, Roy S. Herbst, Ignacio Melero, Jun Wang, Tae Kon Kim, Yu Zhang, Jingwei Sun, Ala F. Nassar, Matthew D. Vesely, Xue Han, Xiaoxiao Cheng, Edward Quinlan, Tianxiang Zhang, Lan Ji, Anthony W. Kim, Dejian Zhao, Ti Badri, Franz Villaroel-Espindola, Shruti S. Desai, Xinxin Nie, Miguel F. Sanmamed
Supplementary Figure Legens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b42d1d289722fcea8e95122286f4ee
https://doi.org/10.1158/2159-8290.22540373
https://doi.org/10.1158/2159-8290.22540373
Autor:
Lieping Chen, Kurt A. Schalper, Roy S. Herbst, Ignacio Melero, Jun Wang, Tae Kon Kim, Yu Zhang, Jingwei Sun, Ala F. Nassar, Matthew D. Vesely, Xue Han, Xiaoxiao Cheng, Edward Quinlan, Tianxiang Zhang, Lan Ji, Anthony W. Kim, Dejian Zhao, Ti Badri, Franz Villaroel-Espindola, Shruti S. Desai, Xinxin Nie, Miguel F. Sanmamed
Supplementary Tables S1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5442f4725dffe22fa245d1106f90e7bc
https://doi.org/10.1158/2159-8290.22540364
https://doi.org/10.1158/2159-8290.22540364
Autor:
Lieping Chen, Kurt A. Schalper, Roy S. Herbst, Ignacio Melero, Jun Wang, Tae Kon Kim, Yu Zhang, Jingwei Sun, Ala F. Nassar, Matthew D. Vesely, Xue Han, Xiaoxiao Cheng, Edward Quinlan, Tianxiang Zhang, Lan Ji, Anthony W. Kim, Dejian Zhao, Ti Badri, Franz Villaroel-Espindola, Shruti S. Desai, Xinxin Nie, Miguel F. Sanmamed
Figures S1-14 and Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ea48a6b171109c1272585e28d38db5
https://doi.org/10.1158/2159-8290.22540367
https://doi.org/10.1158/2159-8290.22540367
Autor:
Lieping Chen, Kurt A. Schalper, Roy S. Herbst, Ignacio Melero, Jun Wang, Tae Kon Kim, Yu Zhang, Jingwei Sun, Ala F. Nassar, Matthew D. Vesely, Xue Han, Xiaoxiao Cheng, Edward Quinlan, Tianxiang Zhang, Lan Ji, Anthony W. Kim, Dejian Zhao, Ti Badri, Franz Villaroel-Espindola, Shruti S. Desai, Xinxin Nie, Miguel F. Sanmamed
Specific mechanisms by which tumor-infiltrating lymphocytes (TIL) become dysfunctional remain poorly understood. Here, we employed a two-pronged approach using single-cell mass cytometry and tissue imaging technologies to dissect TILs from 25 patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2485c178b39280216d7fa52bf73d07
https://doi.org/10.1158/2159-8290.c.6549362
https://doi.org/10.1158/2159-8290.c.6549362
Publikováno v:
Journal of Clinical Oncology. 40:136-136
136 Background: O6-methylguanine DNA methyltransferase (MGMT) is the principal repair mechanism of DNA damage created by alkylating agents. Approximately 40% of colorectal cancers (CRC) exhibit MGMT promoter hypermethylation, expected to result in ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04e73fc430d0e59d73829d7884c3d174
https://doi.org/10.1200/jco.2022.40.4_suppl.136
https://doi.org/10.1200/jco.2022.40.4_suppl.136
Publikováno v:
Journal of Biological Chemistry. 289:5386-5398
Insulinomas (pancreatic islet β cell tumors) are the most common type of functioning pancreatic neuroendocrine tumors that occur sporadically or as a part of the MEN1 syndrome that is caused by germ line mutations in MEN1. Tissue-specific tumor pred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb29bc8194a44c0b2989509d06647bb
https://doi.org/10.1074/jbc.m113.533612
https://doi.org/10.1074/jbc.m113.533612
Pancreatic islet β-cells that lack the MEN1-encoded protein menin develop into tumors. Such tumors express the phosphorylated isoform of the β-cell differentiation transcription factor HLXB9. It is not known how phospho-HLXB9 acts as an oncogenic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36698ff017ae566622dbab1ac117e566
https://europepmc.org/articles/PMC4646204/
https://europepmc.org/articles/PMC4646204/
The multiple endocrine neoplasia type 1 (MEN1) syndrome is caused by germline mutations in the MEN1 gene encoding menin, with tissue-specific tumors of the parathyroids, anterior pituitary, and enteropancreatic endocrine tissues. Also, 30–40% of sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ecabf014fbf5a88feb310b56411cbc
https://europepmc.org/articles/PMC6250975/
https://europepmc.org/articles/PMC6250975/
Autor:
Vaishali I. Parekh, Michael Emmert-Buck, Sita D. Modali, Electron Kebebew, Shruti S. Desai, Sunita K. Agarwal, Russel R. Lonser
Publikováno v:
Cancer Research. 73:LB-249
Rapidly growing evidence shows the emerging tumor suppressor role of large non-coding RNAs (lncRNAs) in cancer pathogenesis. Maternally expressed gene 3 (MEG3) is a lncRNA that belongs to the imprinted DLK1-MEG3 locus located on human chromosome 14q3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e7a92d22b50ef36d93a2de20fb86a2c
https://doi.org/10.1158/1538-7445.am2013-lb-249
https://doi.org/10.1158/1538-7445.am2013-lb-249