Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shruti Regmi"'
Autor:
Brent D. G. Page, Nicholas C. K. Valerie, Roni H. G. Wright, Olov Wallner, Rebecka Isaksson, Megan Carter, Sean G. Rudd, Olga Loseva, Ann-Sofie Jemth, Ingrid Almlöf, Jofre Font-Mateu, Sabin Llona-Minguez, Pawel Baranczewski, Fredrik Jeppsson, Evert Homan, Helena Almqvist, Hanna Axelsson, Shruti Regmi, Anna-Lena Gustavsson, Thomas Lundbäck, Martin Scobie, Kia Strömberg, Pål Stenmark, Miguel Beato, Thomas Helleday
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
NUDIX hydrolases are an important family of nucleotide-metabolizing enzymes. Here, the authors identify potent, small molecule inhibitors of NUDT5, which is implicated in ADP-ribose and 8-oxo-guanine metabolism, and confirm its role in gene regulatio
Externí odkaz:
https://doaj.org/article/2bf99c4671d44e71969d21873ef164c4
Autor:
Brent D. G. Page, Nicholas C. K. Valerie, Roni H. G. Wright, Olov Wallner, Rebecka Isaksson, Megan Carter, Sean G. Rudd, Olga Loseva, Ann-Sofie Jemth, Ingrid Almlöf, Jofre Font-Mateu, Sabin Llona-Minguez, Pawel Baranczewski, Fredrik Jeppsson, Evert Homan, Helena Almqvist, Hanna Axelsson, Shruti Regmi, Anna-Lena Gustavsson, Thomas Lundbäck, Martin Scobie, Kia Strömberg, Pål Stenmark, Miguel Beato, Thomas Helleday
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/8af88760aa3d4c38b6df8ba59624e3f1
Autor:
Saeed Eshtad, Ingrid Almlöf, Pål Stenmark, Matthieu Desroses, Armando Cázares-Körner, Evert Homan, Mikael Altun, Azita Rasti, Si Min Zhang, Torsten Schaller, Lars Bräutigam, Hanna Axelsson, Megan Carter, Adam Throup, Rosa Krimpenfort, Tobias Koolmeister, Daniel Rehling, Ann-Sofie Jemth, Thomas Lundbäck, Elisee Wiita, Thomas Helleday, Anna Hagenkort, Brent D. G. Page, Martin Scobie, Ulrika Warpman Berglund, Linda Pudelko, Antonio Sarno, Andreas Krämer, Christina Kalderén, Juliane Kutzner, Olov A. Wallner, Shruti Regmi, Mona Göttmann, Sean G. Rudd, Nicholas C.K. Valerie, Stefan Knapp, Olga Loseva
Publikováno v:
Nature chemical biology
Nature Chemical Biology
Nature Chemical Biology
The NUDIX hydrolase NUDT15 was originally implicated in sanitizing oxidized nucleotides but was later shown to hydrolyze the active thiopurine metabolites, 6-thio-(d)GTP, thereby dictating the clinical response of this standard-of-care treatment for
Autor:
Thomas Helleday, Shruti Regmi, Roni H. G. Wright, Nicholas C.K. Valerie, Hanna Axelsson, Sean G. Rudd, Sabin Llona-Minguez, Helena Almqvist, Pål Stenmark, Evert Homan, Brent D. G. Page, Olov A. Wallner, Martin Scobie, Fredrik Jeppsson, Thomas Lundbäck, Kia Strömberg, Olga Loseva, Jofre Font-Mateu, Rebecka Isaksson, Pawel Baranczewski, Ingrid Almlöf, Anna-Lena Gustavsson, Miguel Beato, Megan Carter, Ann-Sofie Jemth
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications
Nature Communications
With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine metabolism and was recently identified as a rheosta
Autor:
Sean G. Rudd, Shruti Regmi, Roni H. G. Wright, Evert Homan, Olga Loseva, Thomas Helleday, Sabin Llona-Minguez, Olov A. Wallner, Ingrid Almlöf, Anna-Lena Gustavsson, Jofre Font-Mateu, Rebecka Isaksson, Megan Carter, Ann-Sofie Jemth, Pål Stenmark, Thomas Lundbäck, Helena Almqvist, Pawel Baranczewski, Kia Strömberg, Nicholas C.K. Valerie, Brent D. G. Page, Martin Scobie, Fredrik Jeppsson, Hanna Axelsson, Miguel Beato
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine metabolism and was recently identified as a rheosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248a82c4c016f63cf19a08615089b281
http://hdl.handle.net/20.500.12328/3012
http://hdl.handle.net/20.500.12328/3012
Autor:
Kiran B. Tiwari, Yurika Rajbhandari, Shruti Regmi, Upendra Thapa Shrestha, Mamata Khatri, Junu Hamal
Publikováno v:
International Journal of Life Sciences. 3
Sodium azide was employed to generate mutants of actinomycetes from Mount Everest region, viz. Sagarmatha National Park, Jorsale, Kalapatthar and Namche. Individual isolates of actinomycetes were inoculated on Starch Casein Agar plates containing 10,