Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shruthi, Hamsanathan"'
Autor:
Shruthi Hamsanathan, Aditi U. Gurkar
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Lipids are key macromolecules that perform a multitude of biological functions ranging from maintaining structural integrity of membranes, energy storage, to signaling molecules. Unsurprisingly, variations in lipid composition and its levels can infl
Externí odkaz:
https://doaj.org/article/0c07b81e50af428bacc96ac644612368
Autor:
Umesh K Bageshwar, Lynn VerPlank, Dwight Baker, Wen Dong, Shruthi Hamsanathan, Neal Whitaker, James C Sacchettini, Siegfried M Musser
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149659 (2016)
The twin arginine translocation (Tat) pathway transports fully-folded and assembled proteins in bacteria, archaea and plant thylakoids. The Tat pathway contributes to the virulence of numerous bacterial pathogens that cause disease in humans, cattle
Externí odkaz:
https://doaj.org/article/84100f32452d4002873e775672a5c112
Autor:
Shruthi Hamsanathan, Tamil Anthonymuthu, Suhao Han, Himaly Shinglot, Ella Siefken, Austin Sims, Payel Sen, Hannah L. Pepper, Nathaniel W. Snyder, Hulya Bayir, Valerian Kagan, Aditi U. Gurkar
Publikováno v:
Science advances. 8(7)
Although DNA damage is intricately linked to metabolism, the metabolic alterations that occur in response to DNA damage are not well understood. We use a DNA repair–deficient model of ERCC1-XPF in Caenorhabditis elegans to gain insights on how geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33218314b697ffcf01bfb381e61364c
https://pubmed.ncbi.nlm.nih.gov/35171671
https://pubmed.ncbi.nlm.nih.gov/35171671
Persistent DNA damage rewires lipid metabolism and promotes histone hyperacetylation via MYS-1/Tip60
Autor:
Hannah L. Pepper, Shruthi Hamsanathan, Stacy G. Wendell, Aditi U. Gurkar, Mullet Sj, Payel Sen, SeungHye Han, Tamil S. Anthonymuthu, Nathaniel W. Snyder, Sims Aa, Valerian E. Kagan, Hülya Bayır, Shinglot H, Siefken E
Nuclear DNA damage is intricately linked to cellular metabolism. However, the underlying mechanisms and full range of metabolic alterations that occur in response to persistent DNA damage are not well understood. Here, we use a DNA repair-deficient m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61002edcdf6e59ebcc48eea1c17d3513
https://doi.org/10.1101/2021.06.24.449832
https://doi.org/10.1101/2021.06.24.449832
Autor:
Roshan Karthikappallil, Himaly Shinglot, Lucile Marchal, Suhao Han, Shruthi Hamsanathan, Aditi U. Gurkar
Publikováno v:
Mech Ageing Dev
Although the link between DNA damage and aging is well accepted, the role of different DNA repair proteins on functional/physiological aging is not well-defined. Here, using Caenorhabditis elegans, we systematically examined the effect of three DNA r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f66893755b4a33daa1edbeba3a43b4
https://pubmed.ncbi.nlm.nih.gov/34562508
https://pubmed.ncbi.nlm.nih.gov/34562508
Autor:
Jacobo Sellares, Mauricio Rojas, Shruthi Hamsanathan, Ana L. Mora, Aditi U. Gurkar, Jonathan K. Alder
Publikováno v:
Am J Respir Cell Mol Biol
Senescence is a cell fate decision characterized by irreversible arrest of proliferation accompanied by a senescence-associated secretory phenotype. Traditionally, cellular senescence has been recognized as a beneficial physiological mechanism during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81eb90f2fe67562b58aacc53520b0b4c
https://pubmed.ncbi.nlm.nih.gov/30965013
https://pubmed.ncbi.nlm.nih.gov/30965013
Publikováno v:
FEMS Microbiology Letters. 365
The Tat machinery catalyzes the transport of folded proteins across the cytoplasmic membrane in bacteria and the thylakoid membrane in plants. Transport occurs only in the presence of an electric field (Δψ) and/or a pH (ΔpH) gradient, and thus, Ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce094ddb95f1f808feee08ce0a396f90
https://doi.org/10.1093/femsle/fny123
https://doi.org/10.1093/femsle/fny123
The Tat machinery catalyzes the transport of folded proteins across the bacterial cytoplasmic membrane and the thylakoid membrane in plants. Using fluorescence quenching and cross-linking approaches, we demonstrate that the Escherichia coli TatBC com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c044fc2b418d1de651a208b967819bf1
https://europepmc.org/articles/PMC5770558/
https://europepmc.org/articles/PMC5770558/
Publikováno v:
Journal of Molecular Evolution. Apr2010, Vol. 70 Issue 4, p359-370. 12p. 7 Graphs.
Autor:
Lynn VerPlank, Siegfried M. Musser, Dwight Baker, James C. Sacchettini, Neal Whitaker, Umesh K. Bageshwar, Wen Dong, Shruthi Hamsanathan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0149659 (2016)
PLoS ONE, Vol 11, Iss 2, p e0149659 (2016)
The twin arginine translocation (Tat) pathway transports fully-folded and assembled proteins in bacteria, archaea and plant thylakoids. The Tat pathway contributes to the virulence of numerous bacterial pathogens that cause disease in humans, cattle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2991867a35af65b604f16f76137ab0
https://pubmed.ncbi.nlm.nih.gov/26901445
https://pubmed.ncbi.nlm.nih.gov/26901445