Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Shriyaa Mittal"'
Publikováno v:
Journal of the American Chemical Society. 145:7504-7515
Publikováno v:
ACS Central Science, Vol 4, Iss 9, Pp 1146-1154 (2018)
Externí odkaz:
https://doaj.org/article/394eb26feb044b9dad62bcd3445e819d
Nonenzymatic template-directed RNA primer extension with 2-aminoimidazole activated nucleotides begins with the generation of an imidazolium-bridged dinucleotide intermediate that binds to the template adjacent to the primer. Crystal structures have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9123d56e7fcbc395217b7800ff971c6
https://doi.org/10.1101/2023.02.03.527041
https://doi.org/10.1101/2023.02.03.527041
The virtual circular genome (VCG) model was proposed as a means of going beyond template copying to indefinite cycles of nonenzymatic RNA replication during the origin of life. In the VCG model the protocellular genome is a collection of short oligon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb2d98d5cfb6eba7f808f70eb969f08
https://doi.org/10.1101/2023.01.16.524303
https://doi.org/10.1101/2023.01.16.524303
Autor:
Ziyuan Fang, Harry R.M. Aitken, Constantin Giurgiu, Shriyaa Mittal, Jack W. Szostak, Lydia Pazienza, Seohyun Chris Kim
Publikováno v:
Angew Chem Int Ed Engl
The template-directed synthesis of RNA played an important role in the transition from prebiotic chemistry to the beginnings of RNA based life, but the mechanism of RNA copying chemistry is incompletely understood. We measured the kinetics of templat
Autor:
Sandra Franco Iborra, Jessica Polka, Sara Monaco, Sharon Ahmad, Maryrose Franko, Shriyaa Mittal, Samantha Hindle, R. Dyche Mullins, Timothy E.J. Behrens, Gautam Dey, Iratxe Puebla
There has been strong interest in preprint commenting and review activities in recent years. Public preprint feedback can bring benefits to authors, readers and others in scholarly communication, however, the level of public commenting on preprints i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0a05c7766149a5dafdebc59c910a867
https://doi.org/10.31219/osf.io/9wdcq
https://doi.org/10.31219/osf.io/9wdcq
Publikováno v:
The Journal of Computational Science Education. 9:14-22
Markov State Models (MSMs) are a powerful framework to reproduce the long-time conformational dynamics of biomolecules using a set of short Molecular Dynamics (MD) simulations. However, precise kinetics predictions of MSMs heavily rely on the feature
Autor:
Shriyaa Mittal, Diwakar Shukla
Publikováno v:
The Journal of Physical Chemistry B. 122:10793-10805
Spectroscopic techniques such as Trp-Tyr quenching, luminescence resonance energy transfer, and triplet-triplet energy transfer are widely used for understanding the dynamic behavior of proteins. These experiments measure the relaxation of a particul
Autor:
Diwakar Shukla, Shriyaa Mittal
Spectroscopy experiments are crucial to study membrane proteins for which traditional structure determination methods still prove challenging. Double electron-electron resonance (DEER) spectroscopy experiments provide protein residue-pair distance di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e5b5b0c0933151a74a3ea3a7a7a27b3
https://doi.org/10.1101/2020.12.19.140186
https://doi.org/10.1101/2020.12.19.140186