Assessment of an Antibody-in-Lymphocyte Supernatant Assay for the Etiological Diagnosis of Pneumococcal Pneumonia in Children

Autor: Michael J. Carter, Pallavi Gurung, Claire Jones, Shristy Rajkarnikar, Rama Kandasamy, Meeru Gurung, Stephen Thorson, Madhav C. Gautam, Krishna G. Prajapati, Bibek Khadka, Anju Maharjan, Julian C. Knight, David R. Murdoch, Thomas C. Darton, Merryn Voysey, Brian Wahl, Katherine L. O'Brien, Sarah Kelly, Imran Ansari, Ganesh Shah, Nina Ekström, Merit Melin, Andrew J. Pollard, Dominic F. Kelly, Shrijana Shrestha

Publikováno v: Frontiers in Cellular and Infection Microbiology
King's College London
Frontiers in Cellular and Infection Microbiology, Vol 9 (2020)

New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed41ec685aec85d30e63e8c76f721069
https://pubmed.ncbi.nlm.nih.gov/32039044