Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shrish Kumar, Pandey"'
Autor:
Mithlesh Kumar Temre, Saveg Yadav, Yugal Goel, Shrish Kumar Pandey, Ajay Kumar, Sukh Mahendra Singh
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Neoplastic cells overexpress glucose transporters (GLUT), particularly GLUT1 and GLUT3, to support altered metabolism. Hence, novel strategies are being explored to effectively inhibit GLUTs for a daunting interference of glucose uptake. Glutor, a pi
Externí odkaz:
https://doaj.org/article/0914d44e07ce4c43bfd326b0de7f1c41
Autor:
Yugal Goel, Saveg Yadav, Shrish Kumar Pandey, Mithlesh Kumar Temre, Babu Nandan Maurya, Ashish Verma, Ajay Kumar, Sukh Mahendra Singh
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Methyl jasmonate (MJ), a natural oxylipin, possesses a broad spectrum of antineoplastic potential in vitro. However, its tumor growth impeding and chemo-potentiating action has not been adequately investigated in vivo. Using a murine thymus-derived t
Externí odkaz:
https://doaj.org/article/ad37501f283e49899a24eec0f2c2be3c
Autor:
Yugal Goel, Saveg Yadav, Shrish Kumar Pandey, Mithlesh Kumar Temre, Vinay Kumar Singh, Ajay Kumar, Sukh Mahendra Singh
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Methyl jasmonate (MJ) displays antineoplastic potential against numerous neoplastic cells. However, several mechanistic aspects of its antineoplastic action against malignancies of T cell origin remain elusive. The present investigation reports the n
Externí odkaz:
https://doaj.org/article/2ec150291e704396a35b6a3f4a2a239a
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Malignant cells possess a unique metabolic machinery to endure unobstructed cell survival. It comprises several levels of metabolic networking consisting of 1) upregulated expression of membrane-associated transporter proteins, facilitating unhindere
Externí odkaz:
https://doaj.org/article/d0283e2e310545e389e45677905d8fe4
Autor:
Mithlesh Kumar Temre, Bharti Devi, Vinay Kumar Singh, Yugal Goel, Saveg Yadav, Shrish Kumar Pandey, Rajnish Kumar, Ajay Kumar, Sukh Mahendra Singh
Publikováno v:
Journal of biomolecular structuredynamics.
Recent experimental evidence from our and other laboratories has strongly indicated that glutor, a piperazine-2-one derivative, which is a pan-GLUT inhibitor, displays a promising antineoplastic action by hampering glucose uptake owing to its ability
Autor:
Saveg Yadav, Shrish Kumar Pandey, Vinay Kumar Singh, Yugal Goel, Ajay Kumar, Sukh Mahendra Singh
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176403 (2017)
Altered metabolism is an emerging hallmark of cancer, as malignant cells display a mammoth up-regulation of enzymes responsible for steering their bioenergetic and biosynthetic machinery. Thus, the recent anticancer therapeutic strategies focus on th
Externí odkaz:
https://doaj.org/article/dc9c2e34652545c58f53b0221d417507
Autor:
Ashish Pathak, Shrish Kumar Pandey
Publikováno v:
Concrete Operators, Vol 8, Iss 1, Pp 114-124 (2021)
In this paper, we shall introduce functions spaces as subspaces of Lp κ (ℝ) that we call Besov-κ-Hankel spaces and extend the concept of κ-Hankel wavelet transform in Lp κ(ℝ) space. Subsequently we will characterize the Besov-κ-Hankel space
Publikováno v:
Immunological Investigations. 49:425-442
Tumor growth and its chemotherapeutic regimens manifest myelosuppression, which is one of the possible causes underlying the limited success of immunotherapeutic anticancer strategies. Hence, approaches are being designed to develop safer therapeutic
Publikováno v:
Life Sciences. 215:86-95
Acetate is a short chain fatty acid, comprising carbon, hydrogen and oxygen (C2H3O2−), which has emerged as a key alternative fuel for cellular metabolism. Beginning its voyage from the abiotic atmosphere, acetate has contributed to the physiology
Autor:
Mithlesh Kumar Temre, Sukh Mahendra Singh, Ajay Kumar, Yugal Goel, Saveg Yadav, Shrish Kumar Pandey, Babu Nandan Maurya, Ashish Verma
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Methyl jasmonate (MJ), a natural oxylipin, possesses a broad spectrum of antineoplastic potential in vitro. However, its tumor growth impeding and chemo-potentiating action has not been adequately investigated in vivo. Using a murine thymus-derived t