Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shrimp, JH"'
Autor:
Li, J, Hlavka-Zhang, J, Shrimp, JH, Piper, C, Dupéré-Richér, D, Roth, JS, Jing, D, Casellas Román, HL, Troche, C, Swaroop, A, Kulis, M, Oyer, JA, Will, CM, Shen, M, Riva, A, Bennett, RL, Ferrando, AA, Hall, MD, Lock, RB, Licht, JD
Mutations in epigenetic regulators are common in relapsed pediatric acute lymphoblastic leukemia (ALL). Here, we uncovered the mechanism underlying the relapse of ALL driven by an activating mutation of the NSD2 histone methyltransferase (p.E1099K).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::6117e72f189d2646dc936b4d9c32440f
https://hdl.handle.net/10453/169179
https://hdl.handle.net/10453/169179
Autor:
Hoxie N; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA. Electronic address: nate.hoxie@nih.gov., Calabrese DR; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Itkin Z; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Gomba G; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Shen M; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Verma M; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Janiszewski JS; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Shrimp JH; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Wilson KM; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Michael S; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Hall MD; NIH/NCATS National Institutes of Health/ National Center for the Advancing Translational Sciences, Rockville, MD, USA., Burton L; SCIEX. Concord, ON. Canada., Covey T; SCIEX. Concord, ON. Canada., Liu C; SCIEX. Concord, ON. Canada.
Publikováno v:
SLAS technology [SLAS Technol] 2024 Oct 19; Vol. 29 (6), pp. 100199. Date of Electronic Publication: 2024 Oct 19.
Autor:
Rana S; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Dranchak P; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Dahlin JL; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Lamy L; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Li W; Center for Cancer Research, National Cancer Institute, NIH, Frederick, MD, USA., Oliphant E; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Shrimp JH; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Rajacharya GH; Department of Oncology Science, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA., Tharakan R; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Holland DO; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Whitten AS; Department of Oncology Science, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA., Wilson KM; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Singh PK; Department of Oncology Science, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA; OU Health Stephenson Center, University of Oklahoma Health Science Center, Oklahoma City, OK 73104, USA., Durum SK; Center for Cancer Research, National Cancer Institute, NIH, Frederick, MD, USA., Tao D; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA., Rai G; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA. Electronic address: bantukallug@mail.nih.gov., Inglese J; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, NIH, Rockville, MD 20850, USA; Metabolic Medicine Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA. Electronic address: jinglese@mail.nih.gov.
Publikováno v:
Cell chemical biology [Cell Chem Biol] 2024 Feb 15; Vol. 31 (2), pp. 221-233.e14. Date of Electronic Publication: 2023 Oct 23.
Autor:
Eastman RT; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Rusinova R; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA., Herold KF; Department of Anesthesiology, Weill Cornell Medicine, New York, NY, USA., Huang XP; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.; National Institute of Mental Health Psychoactive Drug Screening Program (NIMH PDSP), University of North Carolina School of Medicine, Chapel Hill, NC, USA., Dranchak P; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Voss TC; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Rana S; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Shrimp JH; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., White AD; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA., Hemmings HC Jr; Department of Anesthesiology, Weill Cornell Medicine, New York, NY, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA., Roth BL; Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.; National Institute of Mental Health Psychoactive Drug Screening Program (NIMH PDSP), University of North Carolina School of Medicine, Chapel Hill, NC, USA.; Division of Chemical Biology and Medicinal Chemistry, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC, USA., Inglese J; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.; Metabolic Medicine Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Andersen OS; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA., Dahlin JL; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 24. Date of Electronic Publication: 2023 Oct 24.
Autor:
Echtenkamp FJ; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Ishida R; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Rivera-Marquez GM; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Maisiak M; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Johnson OT; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California, San Francisco, San Francisco, CA 94158, USA., Shrimp JH; Chemical Genomics Center, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA., Sinha A; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Ralph SJ; Cancure Ltd, Broadbeach, Queensland 4218, Australia., Nisbet I; Cancure Ltd, Broadbeach, Queensland 4218, Australia., Cherukuri MK; Biophysics Section, Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Gestwicki JE; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Disease, University of California, San Francisco, San Francisco, CA 94158, USA., Neckers LM; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Publikováno v:
PNAS nexus [PNAS Nexus] 2023 Apr 03; Vol. 2 (4), pp. pgad115. Date of Electronic Publication: 2023 Apr 03 (Print Publication: 2023).
Autor:
Dahlin JL; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA. jaymedahlin@gmail.com.; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA. jaymedahlin@gmail.com., Hua BK; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA., Zucconi BE; Division of Genetics, Departments of Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Nelson SD Jr; Stanley Center, Broad Institute, Cambridge, MA, USA., Singh S; Imaging Platform, Broad Institute, Cambridge, MA, USA., Carpenter AE; Imaging Platform, Broad Institute, Cambridge, MA, USA., Shrimp JH; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Lima-Fernandes E; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada., Wawer MJ; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA., Chung LPW; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA., Agrawal A; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA., O'Reilly M; Pattern, Broad Institute, Cambridge, MA, USA., Barsyte-Lovejoy D; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada., Szewczyk M; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada., Li F; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada., Lak P; Department of Pharmaceutical Chemistry and Quantitative Biology Institute, University of California San Francisco, San Francisco, CA, USA., Cuellar M; Institute for Therapeutics Discovery and Development, University of Minnesota, Minneapolis, MN, USA., Cole PA; Division of Genetics, Departments of Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA., Meier JL; Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA., Thomas T; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia., Baell JB; Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia., Brown PJ; Structural Genomics Consortium, University of Toronto, Toronto, ON, Canada., Walters MA; Institute for Therapeutics Discovery and Development, University of Minnesota, Minneapolis, MN, USA., Clemons PA; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA., Schreiber SL; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA., Wagner BK; Chemical Biology and Therapeutics Science Program, Broad Institute, Cambridge, MA, USA. bwagner@broadinstitute.org.
Publikováno v:
Nature communications [Nat Commun] 2023 Mar 13; Vol. 14 (1), pp. 1364. Date of Electronic Publication: 2023 Mar 13.
Autor:
Shi L; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; The Cancer Program, Broad Institute, Cambridge, MA, USA., Shen W; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Davis MI; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Kong K; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Vu P; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Saha SK; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Adil R; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Kreuzer J; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Egan R; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Lee TD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Greninger P; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Shrimp JH; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Zhao W; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Wei TY; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Zhou M; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Eccleston J; Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sussman J; Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Manocha U; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Weerasekara V; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; The Cancer Program, Broad Institute, Cambridge, MA, USA., Kondo H; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; The Cancer Program, Broad Institute, Cambridge, MA, USA., Vijay V; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; The Cancer Program, Broad Institute, Cambridge, MA, USA., Wu MJ; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; The Cancer Program, Broad Institute, Cambridge, MA, USA., Kearney SE; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Ho J; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., McClanaghan J; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Murchie E; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Crowther GS; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Patnaik S; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Boxer MB; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA., Ting DT; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Kim WY; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Stanger BZ; Division of Gastroenterology, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Deshpande V; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Ferrone CR; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Benes CH; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Haas W; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA. hallma@mail.nih.gov., Bardeesy N; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA. bardeesy.nabeel@mgh.harvard.edu.; The Cancer Program, Broad Institute, Cambridge, MA, USA. bardeesy.nabeel@mgh.harvard.edu.
Publikováno v:
Nature cancer [Nat Cancer] 2023 Mar; Vol. 4 (3), pp. 365-381. Date of Electronic Publication: 2023 Mar 13.
Autor:
Shrimp JH; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Janiszewski J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Chen CZ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Xu M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Wilson KM; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Kales SC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Sanderson PE; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Shinn P; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Schneider R; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Itkin Z; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Guo H; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Klumpp-Thomas C; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Michael SG; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Zheng W; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Simeonov A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States., Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland 20850, United States.
Publikováno v:
ACS infectious diseases [ACS Infect Dis] 2022 Jun 10; Vol. 8 (6), pp. 1191-1203. Date of Electronic Publication: 2022 Jun 01.
Autor:
Shrimp JH; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Janiszewski J; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Chen CZ; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Xu M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Wilson KM; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Kales SC; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Sanderson PE; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Shinn P; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Itkin Z; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Guo H; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Klumpp-Thomas C; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Michael SG; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Zheng W; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Simeonov A; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850., Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, 20850.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2022 Feb 07. Date of Electronic Publication: 2022 Feb 07.
Autor:
Li J; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Hlavka-Zhang J; Children's Cancer Institute, School of Women's and Children's Health, University of New South Wales Sydney, Sydney, Australia., Shrimp JH; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., Piper C; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Dupéré-Richér D; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Roth JS; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., Jing D; Children's Cancer Institute, School of Women's and Children's Health, University of New South Wales Sydney, Sydney, Australia., Casellas Román HL; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Troche C; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Swaroop A; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Kulis M; Fundació Clínic per a la Recerca Biomèdica, Barcelona, Spain., Oyer JA; Pfizer Inc., Oncology Research and Development, San Diego, California., Will CM; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Shen M; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., Riva A; Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, Florida., Bennett RL; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida., Ferrando AA; Institute of Cancer Genetics, Columbia University, New York, New York., Hall MD; National Center for Advancing Translational Sciences, NIH, Rockville, Maryland., Lock RB; Children's Cancer Institute, School of Women's and Children's Health, University of New South Wales Sydney, Sydney, Australia., Licht JD; Division of Hematology/Oncology, University of Florida Health Cancer Center, Gainesville, Florida. jdlicht@ufl.edu.
Publikováno v:
Cancer discovery [Cancer Discov] 2022 Jan; Vol. 12 (1), pp. 186-203. Date of Electronic Publication: 2021 Aug 20.