Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shrikesh Sachdev"'
Autor:
Austin N. Spratt, Saathvik R. Kannan, Kalicharan Sharma, Shrikesh Sachdev, Shree L. Kandasamy, Anders Sönnerborg, Christian L. Lorson, Kamal Singh
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2593 (2022)
The latest SARS-CoV-2 variant of concern (VOC), Omicron (B.1.1.529), has diversified into more than 300 sublineages. With an expanding number of newly emerging sublineages, the mutation profile is also becoming complicated. There exist mutually exclu
Externí odkaz:
https://doaj.org/article/c3378f2280f0460c9a558ddcc827dff1
Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.
Autor:
David A Roeseler, Shrikesh Sachdev, Desire M Buckley, Trupti Joshi, Doris K Wu, Dong Xu, Mark Hannink, Samuel T Waters
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47366 (2012)
Gbx2 encodes a DNA-binding transcription factor that plays pivotal roles during embryogenesis. Gain-and loss-of-function studies in several vertebrate species have demonstrated a requirement for Gbx2 in development of the anterior hindbrain, spinal c
Externí odkaz:
https://doaj.org/article/7f89cdf969754f2ab493b4f2a1f655d7
Autor:
Saathvik R. Kannan, Shrikesh Sachdev, Athreya S. Reddy, Shree Lekha Kandasamy, Siddappa N. Byrareddy, Christian L. Lorson, Kamal Singh
Publikováno v:
Journal of autoimmunity. 133
Attributes contributing to the current monkeypox virus (MPXV) outbreak remain unknown. It has been established that mutations in viral proteins may alter phenotype and pathogenicity. To assess if mutations in the MPXV DNA replication complex (RC) con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c03ea1f82682819d2bc222b8f498fc
https://pubmed.ncbi.nlm.nih.gov/36252459
https://pubmed.ncbi.nlm.nih.gov/36252459
Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy
Autor:
Ralf Herrmann, Florian von Deimling, Katrin Hoffmann, Sebahattin Cirak, Stephan Hinderlich, Alice Steinbrecher, Wesley J. Errington, Shrikesh Sachdev, Tom H. Lindner, Gilbert G. Privé, Peter Nürnberg, Knut Brockmann, Mark Hannink, Thomas Voit, Carsten G. Bönnemann
Publikováno v:
Brain
Distal myopathies are a heterogeneous group of disorders characterized by progressive weakness and muscular atrophy, beginning in distal limb muscles and affecting proximal limb muscles at a later stage. We studied a large German kindred with 10 affe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4750896ad1808e02b6d4ba60dc137d9
https://doi.org/10.1093/brain/awq108
https://doi.org/10.1093/brain/awq108
Publikováno v:
Biology
DNA polymerases are essential for genome replication, DNA repair and translesion DNA synthesis (TLS). Broadly, these enzymes belong to two groups: replicative and non-replicative DNA polymerases. A considerable body of data suggests that both groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88bcd145b571c0e06a7752a79a6c7bdb
https://doi.org/10.3390/biology7010005
https://doi.org/10.3390/biology7010005
Autor:
Lee D. Spate, Gaurishankar Manandhar, Miriam Sutovsky, Peter Sutovsky, Randall S. Prather, Shrikesh Sachdev, Michael D. Powell, Shawn Zimmerman, Mark Hannink
Publikováno v:
PROTEOMICS - Clinical Applications. 4:337-351
Purpose: Identification of the biomarkers of oocyte quality, and developmental and reprogramming potential is of importance to assisted reproductive technology in humans and animals. Experimental design: PerkinElmer ExacTag™ Kit was used to label d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dcc8236fe695677d5df32bd51e918a
https://doi.org/10.1002/prca.200900024
https://doi.org/10.1002/prca.200900024
Autor:
Andrea Pichler, Frauke Melchior, Rudolf Grosschedl, Heidemarie Sieber, Shrikesh Sachdev, Laurakay Bruhn
Publikováno v:
Genes and Development
The Wnt-responsive transcription factor LEF1 can activate transcription in association with β-catenin and repress transcription in association with Groucho. In search of additional regulatory mechanisms of LEF1 function, we identified the protein in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62200983d59af1f06c5e2edd636dd34c
https://doi.org/10.1101/gad.944801
https://doi.org/10.1101/gad.944801
Autor:
Diana Roberts, Ullas V. Pedmale, Ning Zheng, Pascal Genschik, Mark Hannink, Xiaobo Tang, Shrikesh Sachdev, Emmanuel Liscum, Esther Lechner, Johanna Morrow
Publikováno v:
The Plant cell
The Plant cell, American Society of Plant Biologists (ASPB), 2011, 23, pp.3627-3640
The Plant cell, American Society of Plant Biologists (ASPB), 2011, 23, pp.3627-3640
Plant phototropism is an adaptive response to changes in light direction, quantity, and quality that results in optimization of photosynthetic light harvesting, as well as water and nutrient acquisition. Though several components of the phototropic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad8eda008d1e655dd408a4b1a99fa4a
https://hal.archives-ouvertes.fr/hal-00652259
https://hal.archives-ouvertes.fr/hal-00652259
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 19(4)
Ets-2 controls the activities of many genes characteristically up-regulated in trophoblast. One apparent exception has been the gene for the human chorionic gonadotropin subunit alpha (hCGalpha). Here, we show that the hCGalpha gene contains two over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8311a91d71367a027837899b17d41ea4
https://pubmed.ncbi.nlm.nih.gov/15637148
https://pubmed.ncbi.nlm.nih.gov/15637148
Publikováno v:
Molecular and cellular biology. 20(5)
The inhibitor of kappa B alpha (IkappaBalpha) protein is able to shuttle between the cytoplasm and the nucleus. We have utilized a combination of in vivo and in vitro approaches to provide mechanistic insight into nucleocytoplasmic shuttling by Ikapp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ff7ad4a055f54724e83568647f2613
https://pubmed.ncbi.nlm.nih.gov/10669735
https://pubmed.ncbi.nlm.nih.gov/10669735