Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shrikanth A.G. Reddy"'
Autor:
Shrikanth A.G. Reddy, James L. Abbruzzese, David G. Menter, Kanaga Sabapathy, Murray Korc, Francois-Xavier Claret, Ronghua Zhang, Yixin Yao, Takayuki Asano, Sonyo Shin
Supplementary Figure. 1A. Nuclear extracts (N.E.) from various serum-starved pancreatic cancer cell lines were probed for NF-κBbinding activity. Also included were serum-starved Panc-28 cells after stimulation by IL-1. Supershift assays were perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07670070668bd8cc0027a2787ef1511f
https://doi.org/10.1158/1541-7786.22518562.v1
https://doi.org/10.1158/1541-7786.22518562.v1
Autor:
Shrikanth A.G. Reddy, James L. Abbruzzese, David G. Menter, Kanaga Sabapathy, Murray Korc, Francois-Xavier Claret, Ronghua Zhang, Yixin Yao, Takayuki Asano, Sonyo Shin
Activator protein-1 (AP-1) regulates the expression of several genes involved in human tumorigenesis. However, there is little known about this transcription factor in pancreatic ductal adenocarcinoma. We recently found high levels of AP-1-binding ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87fd7fdec119ba6d3ee6d748fcf419c8
https://doi.org/10.1158/1541-7786.c.6541996
https://doi.org/10.1158/1541-7786.c.6541996
Autor:
Shrikanth A.G. Reddy, Koyamangalath Krishnan, William L. Stone, Sharon Campbell, Sonyo Shin-Kang, Victoria P. Ramsauer, Janet Lightner, Kanishka Chakraborty
Publikováno v:
Free Radical Biology and Medicine. 51:1164-1174
Tocotrienols are members of the vitamin E family but, unlike tocopherols, possess an unsaturated isoprenoid side chain that confers superior anti-cancer properties. The ability of tocotrienols to selectively inhibit the HMG-CoA reductase pathway thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5f979680cfeff8275f8d5b07cfb721
https://doi.org/10.1016/j.freeradbiomed.2011.06.008
https://doi.org/10.1016/j.freeradbiomed.2011.06.008
Autor:
Shrikanth A.G. Reddy, Murray Korc, Takayuki Asano, Yixin Yao, Kanaga Sabapathy, David G. Menter, James L. Abbruzzese, Sonyo Shin, Francois Xavier Claret, Ronghua Zhang
Publikováno v:
Molecular Cancer Research. 7:745-754
Activator protein-1 (AP-1) regulates the expression of several genes involved in human tumorigenesis. However, there is little known about this transcription factor in pancreatic ductal adenocarcinoma. We recently found high levels of AP-1-binding ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befb2389061d911f3763f172af21ee29
https://doi.org/10.1158/1541-7786.mcr-08-0462
https://doi.org/10.1158/1541-7786.mcr-08-0462
Autor:
Shrikanth A.G. Reddy, Akihiro Naito, Masahiro Higuchi, Teresa Evans, Takayuki Asano, Seigo Suzuki
Publikováno v:
Cancer Letters. 268:31-37
TNF plus protein synthesis inhibitor cycloheximide-induced apoptosis in human myelogenous leukemia ML-1a but not in C19, respiration minus mitochondrial DNA-deficient C19 cells, derived from ML-1a. To investigate how mitochondrial DNA depletion inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528f68aabd87391957b8e3db9e403c82
https://doi.org/10.1016/j.canlet.2008.03.020
https://doi.org/10.1016/j.canlet.2008.03.020
Autor:
Bharat B. Aggarwal, Ruijun Shen, Krishna P. Bhat, W. K. Alfred Yung, Shishir Shishodia, Shrikanth A.G. Reddy, Yasanuri Takada, Dimpy Koul
Publikováno v:
Molecular and Cellular Biochemistry. 300:77-87
The continual activation of signaling cascades results in dramatic consequences that include loss of cellular growth control and neoplastic transformation. We show here that phosphoinositide 3-kinase and its mediator Akt was constitutively activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4218f35c875d3ac08cdb7d2d72de4fde
https://doi.org/10.1007/s11010-006-9371-8
https://doi.org/10.1007/s11010-006-9371-8
Publikováno v:
Journal of Computational Biology. 13:1546-1557
Biological signaling networks comprise the chemical processes by which cells detect and respond to changes in their environment. Such networks have been implicated in the regulation of important cellular activities, including cellular reproduction, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be252f88f3770692ac5f95cb27f5c20
https://doi.org/10.1089/cmb.2006.13.1546
https://doi.org/10.1089/cmb.2006.13.1546
Autor:
James L. Abbruzzese, Takayuki Asano, Shrikanth A.G. Reddy, Yixin Yao, Sonyo Shin, James A. McCubrey
Publikováno v:
Cancer Research. 65:9164-9168
Phosphoinositide 3-kinase (PI3K) is activated in pancreatic cancer cells and plays a central role in their proliferation, survival, and drug resistance. Although the mechanism is unclear, PI3K activation in these cells could be due to physical intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d5901e21b0f5d9429365a89d4c69b9
https://doi.org/10.1158/0008-5472.can-05-0779
https://doi.org/10.1158/0008-5472.can-05-0779
Autor:
Yixin Yao, Donghui Li, Jijiang Zhu, Shrikanth A.G. Reddy, James L. Abbruzzese, Takayuki Asano
Publikováno v:
Oncogene. 23:8571-8580
The persistent activation of signaling cascades results in dramatic consequences that include loss of cellular growth control and neoplastic transformation. We show here that phosphoinositide 3-kinase (PI 3-kinase) and its mediator Akt were constitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa6728d6278d7fb9c14fe50e9bd16c4d
https://doi.org/10.1038/sj.onc.1207902
https://doi.org/10.1038/sj.onc.1207902
Publikováno v:
Biochemical and Biophysical Research Communications. 316:1022-1028
Interleukin-1 (IL-1) binds to its type I receptors (IL-1R), which in complex with IL-1R accessory protein (IL-1R AcP) induces various intracellular signaling events. We report here that IL-1 triggers the recruitment of phosphoinositide 3-kinase (PI 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fce35bb726327525ebaf08845469ae
https://doi.org/10.1016/j.bbrc.2004.02.155
https://doi.org/10.1016/j.bbrc.2004.02.155