Výsledky vyhledávání - "Shrikant Kolan"

Akademický článek

Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation

Autor: Jonas Aakre Wik, Danh Phung, Shrikant Kolan, Guttorm Haraldsen, Bjørn Steen Skålhegg, Johanna Hol Fosse

Publikováno v: FEBS Open Bio, Vol 11, Iss 6, Pp 1719-1730 (2021)

Endothelial cell function and metabolism are closely linked to differential use of energy substrate sources and combustion. While endothelial cell migration is promoted by 2‐phosphofructokinase‐6/fructose‐2,6‐bisphosphatase (PFKFB3)‐driven

Externí odkaz: https://doaj.org/article/0eff95fed2ab412194f21fea35b4a63a

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Endogenous glutamine is rate-limiting for anti-CD3 and anti-CD28 induced CD4+ T-cell proliferation and glycolytic activity under hypoxia and normoxia

Autor: Jonas A. Wik, Azazul Chowdhury, Shrikant Kolan, Nasser E. Bastani, Gaoyang Li, Kazi Alam, Franco Grimolizzi, Bjørn S. Skålhegg

Publikováno v: Biochemical Journal. 479:1221-1235

To meet the demand for energy and biomass, T lymphocytes (T cells) activated to proliferation and clonal expansion, require uptake and metabolism of glucose (Gluc) and the amino acid (AA) glutamine (Gln). Whereas exogenous Gln is converted to glutama

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db83a70428896b79347894ef53d29e51
https://doi.org/10.1042/bcj20220144

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