Tumor stiffness is unrelated to myosin light chain phosphorylation in cancer cells.

Autor: Hui-Jun Yu, Leonid A Serebryannyy, Madeline Fry, Madelyne Greene, Olga Chernaya, Wen-Yang Hu, Teng-Leong Chew, Nadim Mahmud, Shrihari S Kadkol, Sarah Glover, Gail Prins, Zuzana Strakova, Primal de Lanerolle

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e79776 (2013)

Many tumors are stiffer than their surrounding tissue. This increase in stiffness has been attributed, in part, to a Rho-dependent elevation of myosin II light chain phosphorylation. To characterize this mechanism further, we studied myosin light cha

Externí odkaz: https://doaj.org/article/b7cdede7dfa544b09dc154618a68221a

AMYLASE DEPLETION SIGNIFICANTLY IMPROVES THE MALDI-TOF PROFILE OF SALIVA – APPLICATION TO COVID-19 DIAGNOSTICS

Autor: Zane LaCasse, Prajkta Chivte, Kari Kress, Venkata Devesh R. Seethi, Joshua Bland, Hamed Alhoori, Shrihari S. Kadkol, Elizabeth R. Gaillard

Human saliva contains a plethora of proteins whose presence and concentration can be monitored for diagnosis and progression of disease. Saliva has been extensively probed for the diagnosis of several systemic and infectious diseases because of the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::27d0cf291b3b16bf8f797247c5291e33
https://doi.org/10.1101/2023.04.11.23288361

MALDI-ToF protein profiling as a potential rapid diagnostic platform for COVID-19

Autor: Pratool Bharti, Prajkta Chivte, Elizabeth R. Gaillard, Venkata Devesh Reddy Seethi, Shrihari S. Kadkol, Zane LaCasse, Joshua Bland

Publikováno v: Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 31-41 (2021)

More than a year after the COVID-19 pandemic was declared, the need still exists for accurate, rapid, inexpensive and non-invasive diagnostic methods that yield high specificity and sensitivity towards the current and newly emerging SARS-CoV-2 strain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577dd0efd6335d910041863dffc117ee
http://europepmc.org/articles/PMC8426322

Development and validation of viral load assays to quantitate SARS-CoV-2

Autor: Ashley Kavanaugh, Lenny Hong, Joshua Bland, Shrihari S. Kadkol

Publikováno v: Journal of Virological Methods

SARS-CoV-2 has infected more than 30 million persons throughout the world. A subset of patients suffer serious consequences that require hospitalization and ventilator support. Current tests for SARS-CoV-2 generate qualitative results and are vital t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73086661ef2a229f9fc33b7ff4580d40
https://doi.org/10.1016/j.jviromet.2021.114100

CRT-100.61 Clinical and Prescribing Outcomes in a Predominantly Minority Population Undergoing Percutaneous Coronary Intervention and CYP2C19 Genotyping

Autor: Shrihari S. Kadkol, Jin Han, James C. Lee, Amer Ardati, Adhir Shroff, Elliott M. Groves

Publikováno v: JACC: Cardiovascular Interventions. 13:S16

The objective of this study was to evaluate post-percutaneous coronary intervention (PCI) prescribing and clinical outcomes in patients receiving CYP2C19 genotype-guided P2Y12 therapy at an urban academic health center serving an ethnically diverse p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3367eb195e66bcdf875961f6a8bc3814
https://doi.org/10.1016/j.jcin.2020.01.044