Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shridhar H. Thorat"'
Publikováno v:
CrystEngComm. 23:3961-3974
Erlotinib, a non-small cell lung cancer BCS class II drug, was found to occur as two polymorphs and two hydrates depending on the crystallization conditions. The monohydrate (form III), which has been reported in patents and publications, is the pref
Publikováno v:
CrystEngComm. 22:6137-6151
Drug–drug cocrystals of anticancer drugs erlotinib and gefitinib with furosemide and mefenamic acid, respectively, have been synthesized. The 1 : 1 erlotinib–furosemide cocrystal crystallizes in the monoclinic centrosymmetric P21/n space group co
Publikováno v:
New Journal of Chemistry. 42:1078-1086
Diastereomeric ‘2RS,4R’-2-arylthiazolidine-4-carboxylic acids (ATCAs) were synthesized and their resolution to chiraly pure N-BOC derivatives was attempted by column chromatography. The absolute stereochemistry of the resolved compounds was ascer
Autor:
Shridhar H. Thorat, Rajesh G. Gonnade, Santosh S. Chavan, Shafeek A. R. Mulla, Taufeekaslam M. Y. Shaikh, Mohsinkhan Y. Pathan
Publikováno v:
ChemistrySelect. 2:9147-9152
A novel one-pot multicomponent reaction (MCR) protocol has been demonstrated for the first time for sustainable and facile synthesis of spirooxindoles and 3, 3’-disubstituted oxindoles in an excellent yield via sp3 C−H activation/functionalizatio
Autor:
Rajesh G. Gonnade, Ray J. Butcher, Sakshi Sharma, V. Haridas, Jerry P. Jasinski, Shridhar H. Thorat
Publikováno v:
European Journal of Organic Chemistry. 2017:1120-1124
We present here a rational design strategy for the synthesis of molecules with figure-eight topology. The design concept was based on the incorporation of turn units in the backbone of the macrocycle. The molecular structure and folding are studied b
Autor:
Debasis Saha, Arnab Mukherjee, Dinesh Mullangi, Aamod V. Desai, Puyam S. Singh, Ankit M. Kansara, Sujit K. Ghosh, Rajesh G. Gonnade, Soumya Mukherjee, Shridhar H. Thorat, Biplab Manna
Publikováno v:
Chemistry - A European Journal. 22:10937-10943
Derived from a strategically chosen hexafluorinated dicarboxylate linker aimed at the designed synthesis of a superhydrophobic metal-organic framework (MOF), the fluorine-rich nanospace of a water-stable MOF (UHMOF-100) exhibits excellent water-repel
Publikováno v:
CrystEngComm. 18:7078-7094
A small library of 13 (3a–m) compounds with modular positioning of iodide and urea/thiourea groups was synthesized in excellent yields in a single step synthetic protocol. The existence of the anticipated (thio)urea derivatives was unambiguously es
Autor:
Rajesh G. Gonnade, Ekta Sangtani, Parthapratim Munshi, Kunal Kumar Jha, Rupesh L. Gawade, Shridhar H. Thorat, Sanjay Kumar Sahu
Publikováno v:
Crystal Growth & Design. 15:5858-5872
Furosemide (FS), a loop diuretic drug commonly used for the treatment of hypertension and edema, exhibited color cocrystal polymorphism with coformer 4,4′-bipyridine (4BPY) in the stoichiometry 2:1, albeit both the API and the cocrystal former are
Autor:
Aslam C. Shaikh, Arunava Maity, Dnyanesh S. Ranade, Rajesh G. Gonnade, Prasad P. Kulkarni, Nitin T. Patil, Shridhar H. Thorat, Parthapratim Munshi
Publikováno v:
Chemical Communications. 51:16115-16118
Molecular fluorophores based on N,C-chelate, four-coordinate organoborons exhibit tunable solid-state emission colors that cover the whole visible region from blue to red. The emission color can be tuned through the substituents on either quinolines
Publikováno v:
Chemical Communications. 51:13690-13693
Presented herein is the reaction of N-heterocyclic carbenes (NHCs) with chalcones resulting in the isolation of the deoxy-Breslow intermediate in the oxidized form. In addition, the tetrahedral intermediate formed by the initial 1,4-addition of NHC t