Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shreyas N. Dahotre"'
Autor:
Lena Gamboa, Shreyas N. Dahotre, Brandon Alexander Holt, Quoc D. Mac, Fang-Yi Su, Anirudh Sivakumar, Gabriel A. Kwong
Publikováno v:
Emerging Technologies in Biophysical Sciences: A World Scientific Reference ISBN: 9789811226083
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed9069c42d04f733bb4ec6bf3a0b520
https://doi.org/10.1142/9789811226113_0001
https://doi.org/10.1142/9789811226113_0001
Autor:
Fang-Yi Su, Qingyang Henry Zhao, Shreyas N. Dahotre, Lena Gamboa, Swapnil Subhash Bawage, Aaron D. Silva Trenkle, Ali Zamat, Hathaichanok Phuengkham, Rafi Ahmed, Philip J. Santangelo, Gabriel A. Kwong
Publikováno v:
Science advances. 8(8)
Simultaneous delivery of mRNA to multiple populations of antigen (Ag)–specific CD8+T cells is challenging given the diversity of peptide epitopes and polymorphism of class I major histocompatibility complexes (MHCI). We developed Ag-presenting nano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc69e1ceb2c64084544c57e76e10195
https://pubmed.ncbi.nlm.nih.gov/35196075
https://pubmed.ncbi.nlm.nih.gov/35196075
Autor:
Lena Gamboa, Ali H. Zamat, Daryll Vanover, Chloé A. Thiveaud, Hannah E. Peck, Hathaichanok Phuengkham, Anirudh Sivakumar, Adrian M. Harris, Shreyas N. Dahotre, Fang-Yi Su, Philip J. Santangelo, Gabriel A. Kwong
CAR T cell immunotherapy relies on CAR targeting of tumor-associated antigens, yet heterogenous antigen expression, interpatient variation, and off-tumor expression by healthy cells remain barriers. Here, we develop synthetic antigens to sensitize so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3dbbada2c580ebfbc394cd30ecd7998
https://doi.org/10.1101/2021.12.11.472238
https://doi.org/10.1101/2021.12.11.472238
Autor:
Fang-Yi Su, Aaron D. Silva Trenkle, Rafi Ahmed, Hathaichanok Phuengkham, Philip J. Santangelo, Shreyas N. Dahotre, Lena Gamboa, Ali Zamat, Qingyang Zhao, Gabriel A. Kwong, Swapnil Subhash Bawage
Simultaneous delivery of mRNA to multiple populations of antigen (Ag)-specific CD8+T cells is challenging given the diversity of peptide epitopes and polymorphism of class I major histocompatibility complexes (MHCI). We developed Ag-presenting nanopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b0ef59010f04a7ccbb9a9404da26a77
https://doi.org/10.1101/2021.10.14.464373
https://doi.org/10.1101/2021.10.14.464373
Publikováno v:
Proceedings of the National Academy of Sciences. 115:4357-4362
The ability to analyze and isolate cells based on the expression of specific surface markers has increased our understanding of cell biology and produced numerous applications for biomedicine. However, established cell-sorting platforms rely on label
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e023f2082d706d85f1e72ed878c284e
https://doi.org/10.1073/pnas.1714820115
https://doi.org/10.1073/pnas.1714820115
Antigen-specific T cells are found at low frequencies in circulation but carry important diagnostic information as liquid biomarkers in numerous biomedical settings, such as monitoring the efficacy of vaccines and cancer immunotherapies. To enable de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccd4661f5810b72e13b39062cccc24e
https://europepmc.org/articles/PMC6399736/
https://europepmc.org/articles/PMC6399736/
Publikováno v:
Adv Ther (Weinh)
Adoptive T cell therapies are transforming the treatment of solid and liquid tumors, yet their widespread adoption is limited in part by the challenge of generating functional cells. T cell activation and expansion using conventional antigen-presenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aec6d3053fe4dc34ecdf622928010d3
https://doi.org/10.1002/adtp.202100034
https://doi.org/10.1002/adtp.202100034
Publikováno v:
Journal of Controlled Release. 178:63-68
A poly(N-isopropylacrylamide-co-acrylamide) (NIPAAm-co-AAm) hydrogel with near-infrared (NIR) absorbing silica–gold nanoshells was designed as a platform for pulsatile delivery of cancer therapeutics. This hydrogel was designed to have a lower crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ebf17dc2522086eb9fd61b6684443e
https://doi.org/10.1016/j.jconrel.2014.01.014
https://doi.org/10.1016/j.jconrel.2014.01.014