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Autor:
Maria L. Avantaggiati, Giuseppe Giaccone, Harvey R Fernandez, Chris Albanese, Mayalin Laforteza, Mikell Paige, Yu-Wen Zhang, Kyu Ah Kim, Shreyas Grade
Publikováno v:
Cancer Research. 76:LB-229
Lung cancer therapy failure is attributed not only to the genetic heterogeneity of tumors, but is also promoted by the functional and phenotypic plasticity of different cell populations. The cancer stem cell (CSC) theory postulates that an under-repr