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pro vyhledávání: '"Shreya Narasimha"'
P62/SQSTM1 is a novel leucine-rich repeat kinase 2 (LRRK2) substrate that enhances neuronal toxicity
Autor:
Marc Bolliger, Anna Memou, Hardy J. Rideout, Alexia F. Kalogeropulou, William H. Wilson, Jing Zhao, R. Jeremy Nichols, Tyler P. Molitor, Shreya Narasimha
Publikováno v:
Biochemical Journal. 475:1271-1293
Autosomal-dominant, missense mutations in the leucine-rich repeat protein kinase 2 (LRRK2) gene are the most common genetic predisposition to develop Parkinson's disease (PD). LRRK2 kinase activity is increased in several pathogenic mutations (N1437H
Publikováno v:
Frontiers in Systems Neuroscience, Vol 14 (2021)
Several physiology signals, including heart rate and pupil size, have been widely used as peripheral indices of arousal to evaluate the effects of arousal on brain functions. However, whether behavior depends differently on arousal indexed by these p
Externí odkaz:
https://doaj.org/article/610cdad5fc034c36a495dde2b41852ee