Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shreya Dharadhar"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 21, Iss , Pp - (2020)
TRIM family of E3 ubiquitin ligases have an amino-terminal conserved tripartite motif consisting of RING, B-Box, coiled-coil domain and different C-terminal domain leading it to classification into 11 subclasses. TRIM72 is an E3 ligase of class IV an
Externí odkaz:
https://doaj.org/article/4c20597c16a94d51a7a24be481592923
Autor:
Doreth Bhairosing-Kok, Flora S. Groothuizen, Alexander Fish, Titia K. Sixma, Shreya Dharadhar, Herrie H.K. Winterwerp
Publikováno v:
Nucleic Acids Research
'Nucleic Acids Research ', vol: 47, pages: 8888-8898 (2019)
'Nucleic Acids Research ', vol: 47, pages: 8888-8898 (2019)
DNA mismatch repair (MMR) corrects mismatches, small insertions and deletions in DNA during DNA replication. While scanning for mismatches, dimers of MutS embrace the DNA helix with their lever and clamp domains. Previous studies indicated generic fl
Publikováno v:
EMBO Reports
During DNA replication, the deubiquitinating enzyme USP1 limits the recruitment of translesion polymerases by removing ubiquitin marks from PCNA to allow specific regulation of the translesion synthesis (TLS) pathway. USP1 activity depends on an allo
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 21, Iss, Pp-(2020)
Biochemistry and Biophysics Reports, Vol 21, Iss, Pp-(2020)
TRIM family of E3 ubiquitin ligases have an amino-terminal conserved tripartite motif consisting of RING, B-Box, coiled-coil domain and different C-terminal domain leading it to classification into 11 subclasses. TRIM72 is an E3 ligase of class IV an
Publikováno v:
Methods in enzymology. 618
Ubiquitin-specific proteases (USPs) are an important class of deubiquitinating enzymes (DUBs) that carry out critical roles in cellular physiology and are regulated at multiple levels. Quantitative characterization of USP activity is crucial for mech
Ubiquitin-specific proteases (USPs) are an important class of deubiquitinating enzymes (DUBs) that carry out critical roles in cellular physiology and are regulated at multiple levels. Quantitative characterization of USP activity is crucial for mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::217feb2249d239cbdfba1c493c1249c9
https://doi.org/10.1016/bs.mie.2018.12.023
https://doi.org/10.1016/bs.mie.2018.12.023
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 84:1761-1766
Monopolar spindle 1 (Mps1, also known as TTK) is a protein kinase crucial for ensuring that cell division progresses to anaphase only after all chromosomes are connected to spindle microtubules. Incomplete chromosomal attachment leads to abnormal chr
Publikováno v:
Proteins. 84(12)
Monopolar spindle 1 (Mps1, also known as TTK) is a protein kinase crucial for ensuring that cell division progresses to anaphase only after all chromosomes are connected to spindle microtubules. Incomplete chromosomal attachment leads to abnormal chr
Publikováno v:
Journal of Structural Biology
Regulation of deubiquitinating enzyme (DUB) activity is an essential step for proper function of cellular ubiquitin signals. UAF1 is a WD40 repeat protein, which binds and activates three important DUBs, USP1, USP12 and USP46. Here, we report the cry