Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shreya Chand"'
Autor:
Pabitra K. Sahoo, Seung Joon Lee, Poonam B. Jaiswal, Stefanie Alber, Amar N. Kar, Sharmina Miller-Randolph, Elizabeth E. Taylor, Terika Smith, Bhagat Singh, Tammy Szu-Yu Ho, Anatoly Urisman, Shreya Chand, Edsel A. Pena, Alma L. Burlingame, Clifford J. Woolf, Mike Fainzilber, Arthur W. English, Jeffery L. Twiss
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
G3BP1 is RasGAP SH3 domain binding protein 1 that interacts with 48S pre-initiation complex when translation is stalled. Here, Twiss and colleagues show that neuronal G3BP1 can negatively regulate axonal mRNA translation, and inhibit axonal regenerat
Externí odkaz:
https://doaj.org/article/54f17aef7ce54eff8c30573b11316ce9
Autor:
Joanna P Rys, Christopher C DuFort, David A Monteiro, Michelle A Baird, Juan A Oses-Prieto, Shreya Chand, Alma L Burlingame, Michael W Davidson, Tamara N Alliston
Publikováno v:
eLife, Vol 4 (2015)
Cell surface receptors are central to the cell's ability to generate coordinated responses to the multitude of biochemical and physical cues in the microenvironment. However, the mechanisms by which receptors enable this concerted cellular response r
Externí odkaz:
https://doaj.org/article/5f5eb2ea378949ea8e38fcd7184ece77
Autor:
Riki Kawaguchi, Jeffery L. Twiss, David Oliver, Amar N. Kar, Pabitra K. Sahoo, Meir Rozenbaum, Ross J. Taylor, Alma L. Burlingame, Michael Shtutman, Seung Joon Lee, Hao Ji, Juan A. Oses-Prieto, Sharmina Miller-Randolph, Shreya Chand, Giovanni Coppola, Mike Fainzilber
Publikováno v:
Molecular & cellular proteomics : MCP, vol 17, iss 11
mRNA translation in axons enables neurons to introduce new proteins at sites distant from their cell body. mRNA-protein interactions drive this post-transcriptional regulation, yet knowledge of RNA binding proteins (RBP) in axons is limited. Here we
Autor:
Clifford J. Woolf, Edsel A. Peña, Stefanie Alber, Poonam B. Jaiswal, Alma L. Burlingame, Terika P. Smith, Jeffery L. Twiss, Amar N. Kar, Elizabeth E. Taylor, Arthur W. English, Pabitra K. Sahoo, Mike Fainzilber, Anatoly Urisman, Shreya Chand, Seung Joon Lee, Sharmina Miller-Randolph, Tammy Szu-Yu Ho, Bhagat Singh
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature communications, vol 9, iss 1
Nature Communications
Nature communications, vol 9, iss 1
Nature Communications
Critical functions of intra-axonally synthesized proteins are thought to depend on regulated recruitment of mRNA from storage depots in axons. Here we show that axotomy of mammalian neurons induces translation of stored axonal mRNAs via regulation of
Autor:
Martina Sanlorenzo, Sarasa T. Kim, Rosaura Esteve-Puig, Kevin Lai, Gary M. Green, Susana Ortiz-Urda, Shreya Chand, Klemens Rappersberger, Alma L. Burlingame, Mitchell Zekhtser, Juan A. Oses-Prieto, Jeffrey Ma, Brian D. Cholewa, Christian Posch, Renate Panzer-Grümayer, Igor Vujic
Publikováno v:
The Journal of investigative dermatology, vol 136, iss 10
In melanoma, mutant and thereby constantly active neuroblastoma rat sarcoma (NRAS) affects 15-20% of tumors, contributing to tumor initiation, growth, invasion, and metastasis. Recent therapeutic approaches aim to mimic RAS extinction by interfering
Publikováno v:
JSES International, Vol 7, Iss 6, Pp 2473-2475 (2023)
Background: Patient-reported outcome measures (PROMs) are increasingly used to evaluate outcomes in patients undergoing shoulder arthroplasty. The Patient-Reported Outcome Measures Information System (PROMIS) is popular due to low cost and question b
Externí odkaz:
https://doaj.org/article/c4d4f6f600ee408d994dc9d103f67315
Autor:
Robert Damoiseaux, Michelle Y. S. Shih, Harley I. Kornblum, Jonathan Nakashima, Nicholas Orozco, Koppany Visnyei, Thomas J. Crisman, Shreya Chand, Kirsten Ludwig, Daniel Azzam, Anjelica Cardenas, Michael C. Condro, Juan A. Oses-Prieto, Alvaro G. Alvarado, Fuying Gao, Alma L. Burlingame, Ankur A. Gholkar, Serli Nazarian, Jorge Z. Torres, Jantzen Sperry, Dan R. Laks, Giovanni Coppola
Publikováno v:
Neuro-oncology, vol 20, iss 6
Laks, DR; Oses-Prieto, JA; Alvarado, AG; Nakashima, J; Chand, S; Azzam, DB; et al.(2018). A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma. NEURO-ONCOLOGY, 20(6), 764-775. doi: 10.1093/neuonc/nox215. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8001k7vm
Laks, DR; Oses-Prieto, JA; Alvarado, AG; Nakashima, J; Chand, S; Azzam, DB; et al.(2018). A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma. NEURO-ONCOLOGY, 20(6), 764-775. doi: 10.1093/neuonc/nox215. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8001k7vm
Author(s): Laks, Dan R; Oses-Prieto, Juan A; Alvarado, Alvaro G; Nakashima, Jonathan; Chand, Shreya; Azzam, Daniel B; Gholkar, Ankur A; Sperry, Jantzen; Ludwig, Kirsten; Condro, Michael C; Nazarian, Serli; Cardenas, Anjelica; Shih, Michelle YS; Damoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ee1ce385c3ecd208aa4aa8a9546055
https://escholarship.org/uc/item/8001k7vm
https://escholarship.org/uc/item/8001k7vm
Autor:
Shreya Chand, Shilpi Mahajan, Burcu Hasdemir, Dimitris K. Grammatopoulos, Michael J. Woolley, Aditi Bhargava, Alma L. Burlingame, Juan A. Oses-Prieto
Publikováno v:
Molecular biology of the cell, vol 28, iss 18
Molecular Biology of the Cell
Molecular Biology of the Cell
A physical interaction is shown between CRF1R and CRF2R, two class B G protein–coupled receptors that mediate stress and immune responses. Trafficking of CRF2R but not CRF1R is actin dependent, and coexpression of the two receptors alters actin-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06283358155b591d54cb93eb5098c80
https://escholarship.org/uc/item/87j2w394
https://escholarship.org/uc/item/87j2w394
Autor:
Jessica K. Roberts, Shreya Chand, Philip L. Ballard, Anne Marie Barrette, Alma L. Burlingame, Mark R. Segal, Edmund A. Egan, Juan A. Oses-Prieto, Cheryl J. Chapin
Publikováno v:
American journal of respiratory cell and molecular biology, vol 55, iss 5
Barrette, AM; Roberts, JK; Chapin, C; Egan, EA; Segal, MR; Oses-Prieto, JA; et al.(2016). Antiinflammatory Effects of Budesonide in Human Fetal Lung. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 55(5), 623-632. doi: 10.1165/rcmb.2016-0068OC. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9tt8794j
Barrette, AM; Roberts, JK; Chapin, C; Egan, EA; Segal, MR; Oses-Prieto, JA; et al.(2016). Antiinflammatory Effects of Budesonide in Human Fetal Lung. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 55(5), 623-632. doi: 10.1165/rcmb.2016-0068OC. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9tt8794j
Lung inflammation in premature infants contributes to the development of bronchopulmonary dysplasia (BPD), a chronic lung disease with long-term sequelae. Pilot studies administering budesonide suspended in surfactant have found reduced BPD without t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee1dea588911b3627f3528f3c981a0d7
https://escholarship.org/uc/item/9tt8794j
https://escholarship.org/uc/item/9tt8794j
Autor:
Kevin Lai, Juan A. Oses-Prieto, Kevin Lin, Martina Sanlorenzo, Shreya Chand, D. Lee, José Luis Rodríguez-Peralto, Jeffrey Ma, Susana Ortiz-Urda, Marin Vujic, Christian Posch, Igor Vujic, Alma L. Burlingame
Publikováno v:
Journal of proteomics. 144
Mutations in the proto-oncogene c-KIT (KIT) are found in several cancers, and the site of these mutations differs markedly between cancer types. We used site directed mutagenesis to induce KIT559, KIT642 and KIT816 mutations in primary human melanocy