Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shrey Sindhwani"'
Autor:
Shrey Sindhwani, Zachary P. Lin, Ben Ouyang, Jessica Ngai, Benjamin R. Kingston, Presley MacMillan, Abdullah Muhammad Syed, Warren C. W. Chan
Publikováno v:
ACS Nano. 15:14080-14094
The successful delivery of nanoparticles to solid tumors depends on their ability to pass through blood vessels and into the tumor microenvironment. Here, we discovered a subset of tumor endothelial cells that facilitate nanoparticle transport into s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38d09c859d5c6616457d2e6ff903b7d
https://doi.org/10.1021/acsnano.1c04510
https://doi.org/10.1021/acsnano.1c04510
Autor:
Jonathan R. Krieger, Shrey Sindhwani, Fayi Song, Benjamin Stordy, James Lazarovits, Yuwei Zhang, Julie Audet, Abdullah Muhammad Syed, Anthony J. Tavares, Warren C. W. Chan
Publikováno v:
ACS Nano. 13:8023-8034
The surface of nanoparticles changes immediately after intravenous injection because blood proteins adsorb on the surface. How this interface changes during circulation and its impact on nanoparticle distribution within the body is not understood. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3914bd770597d6c89970046700801113
https://doi.org/10.1021/acsnano.9b02774
https://doi.org/10.1021/acsnano.9b02774
Autor:
Warren C. W. Chan, Shrey Sindhwani
Publikováno v:
Journal of internal medicineReferences. 290(3)
The field of nanotechnology has been a significant research focus in the last thirty years. This emphasis is due to the unique optical, electrical, magnetic, chemical and biological properties of materials approximately ten thousand times smaller tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307d58cf77974aa08ef3fa7c05f5211d
https://pubmed.ncbi.nlm.nih.gov/33480120
https://pubmed.ncbi.nlm.nih.gov/33480120
Autor:
Maneesha A Rajora, Marta Overchuk, Danielle M. Charron, Brian C. Wilson, Shrey Sindhwani, Warren C. W. Chan, Gang Zheng, Martin G. Pomper, Abdullah Muhammad Syed, Adam Koebel, Juan Chen, Kara M. Harmatys
Publikováno v:
Nano letters. 21(1)
Limited tumor nanoparticle accumulation remains one of the main challenges in cancer nanomedicine. Here, we demonstrate that subtherapeutic photodynamic priming (PDP) enhances the accumulation of nanoparticles in subcutaneous murine prostate tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69bac7275dbfcbb5d434dca22d3431b1
https://pubmed.ncbi.nlm.nih.gov/33301689
https://pubmed.ncbi.nlm.nih.gov/33301689
Autor:
Pablo Llano-Suárez, Stefan Wilhelm, Warren C. W. Chan, Benjamin R. Kingston, Suresh Gadde, Abdullah Muhammad Syed, Shrey Sindhwani, Zachary Pengju Lin, Ben Ouyang, Jamie L. Y. Wu, Jessica Ngai, Zaina Kahiel, Presley MacMillan
Publikováno v:
Nano letters. 20(2)
Three-dimensional (3D) optical microscopy can be used to understand and improve the delivery of nanomedicine. However, this approach cannot be performed for analyzing liposomes in tissues because the processing step to make tissues transparent for im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea9b80dd417ebe607672e4ecdb53b19
https://pubmed.ncbi.nlm.nih.gov/31928014
https://pubmed.ncbi.nlm.nih.gov/31928014
Publikováno v:
Small Methods. 6:2101233
Diagnostic tests can detect diseases, monitor responses, and inform treatments. They are vital to the effective management of disease. There have been significant advances in the engineering of new diagnostic technologies. These technologies may forg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ac606b8afea7a02dbecb41a1705201
https://doi.org/10.1002/smtd.202101233
https://doi.org/10.1002/smtd.202101233
Autor:
Qin Dai, Stefan Wilhelm, Yih Yang Chen, Warren C. W. Chan, Ding Ding, Shrey Sindhwani, Abdullah Muhammad Syed, Presley MacMillan, Yuwei Zhang
Publikováno v:
ACS Nano. 12:8423-8435
Coating the nanoparticle surface with cancer cell recognizing ligands is expected to facilitate specific delivery of nanoparticles to diseased cells in vivo. While this targeting strategy is appealing, no nanoparticle-based active targeting formulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082d6d7fdf61effdf655180604859fc9
https://doi.org/10.1021/acsnano.8b03900
https://doi.org/10.1021/acsnano.8b03900
Publikováno v:
Nature Reviews Materials. 6:1070-1070
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7094bec7c2aced8b01db8cae346dc58d
https://doi.org/10.1038/s41578-021-00391-z
https://doi.org/10.1038/s41578-021-00391-z
Autor:
Warren C. W. Chan, Stefan Wilhelm, Dennis S. W. Lee, Jennifer L. Gommerman, Benjamin R. Kingston, Shrey Sindhwani, Abdullah Muhammad Syed
Publikováno v:
Journal of the American Chemical Society. 139:9961-9971
Chemical probes are key components of the bioimaging toolbox, as they label biomolecules in cells and tissues. The new challenge in bioimaging is to design chemical probes for three-dimensional (3D) tissue imaging. In this work, we discovered that li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9ec0efa4cbfe3074cc4a7d2b11fd59
https://doi.org/10.1021/jacs.7b04022
https://doi.org/10.1021/jacs.7b04022
Autor:
Abdullah Muhammad Syed, Warren C. W. Chan, Pamuditha N. Silva, Yih Yang Chen, Shrey Sindhwani, Jonathan V. Rocheleau
Publikováno v:
Proceedings of the National Academy of Sciences. 113:14915-14920
On-chip imaging of intact three-dimensional tissues within microfluidic devices is fundamentally hindered by intratissue optical scattering, which impedes their use as tissue models for high-throughput screening assays. Here, we engineered a microflu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3267ee382118816d3b4e516146f5f3f0
https://doi.org/10.1073/pnas.1609569114
https://doi.org/10.1073/pnas.1609569114