Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Shreshtha Rojesh"'
Autor:
Ji Young Kim, Yuntao Bai, Laura A. Jayne, Ralph D. Hector, Avinash K. Persaud, Su Sien Ong, Shreshtha Rojesh, Radhika Raj, Mei Ji He Ho Feng, Sangwoon Chung, Rachel E. Cianciolo, John W. Christman, Moray J. Campbell, David S. Gardner, Sharyn D. Baker, Alex Sparreboom, Rajgopal Govindarajan, Harpreet Singh, Taosheng Chen, Ming Poi, Katalin Susztak, Stuart R. Cobb, Navjot Singh Pabla
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Protein kinases have emerged as critical regulators of disease pathogenesis. Here, the authors have utilized kinome-wide screening approaches to reveal a pathogenic role of CDKL5 kinase in acute kidney injury, which is dependent on suppression of a S
Externí odkaz:
https://doaj.org/article/f36413dcdc0f4c47bbdac00ac1a34b20
Autor:
Katalin Susztak, Taosheng Chen, John W. Christman, Yuntao Bai, Stuart Cobb, Ming Poi, Harpreet Singh, Sharyn D. Baker, Rajgopal Govindarajan, Rachel E. Cianciolo, Jiyoung Kim, Sangwoon Chung, Radhika Raj, Alex Sparreboom, Laura A. Jayne, Navjotsingh Pabla, Shreshtha Rojesh, David S. Gardner, Ralph D. Hector, Moray J. Campbell, Mei Ji He Ho Feng, Avinash K. Persaud, Su Sien Ong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Kim, J Y, Bai, Y, Jayne, L A, Hector, R, Persaud, A K, Ong, S S, Rojesh, S, Feng, M J H H, Chung, S, Cianciolo, R E, Christman, J W, Campbell, M J, Gardner, D S, Baker, S D, Sparreboom, A, Govindarajan, R, Singh, H, Chen, T, Po, M, Susztak, K, Cobb, S & Pabla, N S 2020, ' A Kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury ', Nature Communications . https://doi.org/10.1038/s41467-020-15638-6
Kim, J Y, Bai, Y, Jayne, L A, Hector, R, Persaud, A K, Ong, S S, Rojesh, S, Feng, M J H H, Chung, S, Cianciolo, R E, Christman, J W, Campbell, M J, Gardner, D S, Baker, S D, Sparreboom, A, Govindarajan, R, Singh, H, Chen, T, Po, M, Susztak, K, Cobb, S & Pabla, N S 2020, ' A Kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury ', Nature Communications . https://doi.org/10.1038/s41467-020-15638-6
Renal tubular epithelial cells (RTECs) perform the essential function of maintaining the constancy of body fluid composition and volume. Toxic, inflammatory, or hypoxic-insults to RTECs can cause systemic fluid imbalance, electrolyte abnormalities an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5c57fa795f052eac079df1d6607f67
https://doaj.org/article/f36413dcdc0f4c47bbdac00ac1a34b20
https://doaj.org/article/f36413dcdc0f4c47bbdac00ac1a34b20