Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shreerang A Bhide"'
Autor:
Isla Leslie, Kate Newbold, Pablo Nenclares, Lucinda Gunn, Heba Soliman, Mateo Bover, Amy Trinh, Kee Howe Wong, Chris M Nutting, Derfel ap Dafydd, Shreerang A Bhide
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Previous studies have suggested that inflammatory markers (neutrophil-to-lymphocyte ratio (NLR), lactate dehydrogenase (LDH) and fibrinogen) are prognostic biomarkers in patients with a variety of solid cancers, including those treated wit
Externí odkaz:
https://doaj.org/article/80225158d9a34767b69b73a1138ee17b
Autor:
Marco Borri, Maria A Schmidt, Ceri Powell, Dow-Mu Koh, Angela M Riddell, Mike Partridge, Shreerang A Bhide, Christopher M Nutting, Kevin J Harrington, Katie L Newbold, Martin O Leach
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138545 (2015)
PURPOSE:To describe a methodology, based on cluster analysis, to partition multi-parametric functional imaging data into groups (or clusters) of similar functional characteristics, with the aim of characterizing functional heterogeneity within head a
Externí odkaz:
https://doaj.org/article/0188356f33854b9cb081b39028b4680d
Autor:
Shane Zaidi, Martin McLaughlin, Shreerang A Bhide, Suzanne A Eccles, Paul Workman, Christopher M Nutting, Robert A Huddart, Kevin J Harrington
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35436 (2012)
Heat shock protein 90 (HSP90) is a molecular chaperone responsible for the conformational maintenance of a number of client proteins that play key roles in cell cycle arrest, DNA damage repair and apoptosis following radiation. HSP90 inhibitors exhib
Externí odkaz:
https://doaj.org/article/08a586a1c76b454e94482aefa4f9bc63
Autor:
Pablo Nenclares, Adrian Larkeryd, Floriana Manodoro, Jen Y. Lee, Susan Lalondrelle, Duncan C. Gilbert, Marco Punta, Ben O’Leary, Antonio Rullan, Anguraj Sadanandam, Benny Chain, Alan Melcher, Kevin J. Harrington, Shreerang A. Bhide
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundThe effect of chemoradiation on the anti-cancer immune response is being increasingly acknowledged; however, its clinical implications in treatment responses are yet to be fully understood. Human papillomavirus (HPV)-driven malignancies exp
Externí odkaz:
https://doaj.org/article/dfbf765b6f314f468732baee3f145325
Autor:
Stacey J. Bryan, Jen Lee, Richard Gunu, Allison Jones, Adeola Olaitan, Adam N. Rosenthal, Ros J. Cutts, Isaac Garcia-Murillas, Nick Turner, Susan Lalondrelle, Shreerang A. Bhide
Publikováno v:
Cancers, Vol 15, Iss 9, p 2590 (2023)
Background: High-risk HPV infection is responsible for >99% of cervix cancers (CC). In persistent infections that lead to cancer, the tumour breaches the basement membrane, releasing HPV-DNA into the bloodstream (cHPV-DNA). A next-generation sequenci
Externí odkaz:
https://doaj.org/article/79198e0181da4cfcb09a4f4898e00a85
Autor:
Susan Lalondrelle, Jen Lee, Rosalind J. Cutts, Isaac Garcia Murillas, Nik Matthews, Nicholas Turner, Kevin Harrington, Katherine Vroobel, Emily Moretti, Shreerang A. Bhide
Publikováno v:
Cancers, Vol 15, Iss 5, p 1387 (2023)
Background: The majority of locally advanced cervical cancers (LaCC) are causally related to HPV. We sought to investigate the utility of an ultra-sensitive HPV-DNA next generation sequencing (NGS) assay—panHPV-detect—in LaCC treated with chemora
Externí odkaz:
https://doaj.org/article/4005ecb0034c4137a63c400d206bcc3e
Autor:
Kevin J. Harrington, Martin McLaughlin, Christopher M. Nutting, Kate L. Newbold, Shreerang A. Bhide, Hind Hafsi, Malin Pedersen, Holly E. Barker, Magnus T. Dillon
Supplementary figures 1-4, supplementary table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d33e773df37337cb3f3754278872ff2
https://doi.org/10.1158/1535-7163.22508769.v1
https://doi.org/10.1158/1535-7163.22508769.v1
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
Scatter plots comparing individual MRI measurements (tumor volume, baseline R2* and percentage of fluctuating volume) against pathology (Hoechst 33342 uptake for perfusion, pimonidazole adduct formation for hypoxia) determined from the cohort of CALR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5643aca51f2f005b04bc89db1f4677
https://doi.org/10.1158/1078-0432.22467878
https://doi.org/10.1158/1078-0432.22467878
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
Fluctuating volume percentages detected for HNSCC metastatic lymph node ROIs between two MR sessions 48 hours apart (solid lines - responders, dashed lines - non responders).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326904d68cc016e10569a6c3076ba96c
https://doi.org/10.1158/1078-0432.22467863
https://doi.org/10.1158/1078-0432.22467863
Autor:
Kate L. Newbold, Simon P. Robinson, Martin O. Leach, Suzanne A. Eccles, Carol Box, Cheryl Richardson, Georgina Hopkinson, Christopher M. Nutting, Kevin J. Harrington, Shreerang A. Bhide, James A. d'Arcy, Dualta Mcquaid, Alex Dunlop, Dow-Mu Koh, Angela M. Riddell, Kee H. Wong, Maria A. Schmidt, Lauren C.J. Baker, Liam Welsh, Rafal Panek
Examples of Ktrans and R2* distributions for fluctuating and non-fluctuating parts of human HNSCC (Patient No 5, N2). The non-enhancing part of the tumor (Ktrans = 0) is indicated with an asterisk.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a8b62ffcddd331f0a69c8105b7a2cd
https://doi.org/10.1158/1078-0432.22467866.v1
https://doi.org/10.1158/1078-0432.22467866.v1