Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shreena Joshi"'
Autor:
Alison M. Gurney, Roman Mizera, Vojtech Sedivy, Youssef Ghaly, Marie Zaloudikova, Jana Novotná, Jan Herget, Shreena Joshi, Sean Brennan
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Hypoxic pulmonary vasoconstriction (HPV) is a beneficial mechanism that diverts blood from hypoxic alveoli to better ventilated areas of the lung, but breathing hypoxic air causes the pulmonary circulation to become hypertensive. Responses to airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989ccd24974a88e5a777ac043e6152b0
https://doi.org/10.1152/ajplung.00362.2013
https://doi.org/10.1152/ajplung.00362.2013
Autor:
Shreena Joshi, Karen D. McCloskey, Louise Johnston, Christopher Carson, U.A. Anderson, Alison M. Gurney
Publikováno v:
British Journal of Pharmacology. 169:1290-1304
Background and Purpose The aim of the study was to determine whether KCNQ channels are functionally expressed in bladder smooth muscle cells (SMC) and to investigate their physiological significance in bladder contractility.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3dc7bf2fd5a5571b6dc133a331d534
https://doi.org/10.1111/bph.12210
https://doi.org/10.1111/bph.12210
Publikováno v:
British Journal of Pharmacology. 165:455-466
BACKGROUND AND PURPOSE: Relaxation of corpus cavernosum smooth muscle (CCSM) is induced by NO. NO promotes the formation of cGMP, which activates cGMP-dependent protein kinase I (PKGI). The large conductance calcium-activated potassium (BK(Ca) ) chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3e5ffce4c91d52b6891a4c9508e6826
https://doi.org/10.1111/j.1476-5381.2011.01569.x
https://doi.org/10.1111/j.1476-5381.2011.01569.x
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 329:368-376
Potassium channels are central to the regulation of pulmonary vascular tone. The smooth muscle cells of pulmonary artery display a background K+ conductance with biophysical properties resembling those of KCNQ (KV7) potassium channels. Therefore, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a704f9fd88b97a2ce5b3ba6c9cd72e
https://doi.org/10.1124/jpet.108.147785
https://doi.org/10.1124/jpet.108.147785
Publikováno v:
British journal of pharmacology. 165(2)
Relaxation of corpus cavernosum smooth muscle (CCSM) is induced by NO. NO promotes the formation of cGMP, which activates cGMP-dependent protein kinase I (PKGI). The large conductance calcium-activated potassium (BK(Ca) ) channel is regarded as a maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9098dee96728b74d8867aa94649988e
https://pubmed.ncbi.nlm.nih.gov/21718308
https://pubmed.ncbi.nlm.nih.gov/21718308
Publikováno v:
Journal of Urology. 185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c62a104ac0684e95037199d4dfd442e
https://doi.org/10.1016/j.juro.2011.02.719
https://doi.org/10.1016/j.juro.2011.02.719
Publikováno v:
Advances in experimental medicine and biology. 661
Smooth muscle cells regulate the diameter of pulmonary arteries and the resistance to blood flow in the pulmonary circulation. These cells are normally relaxed to maintain low intrinsic vessel tone, but are contracted in pulmonary arterial hypertensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e530ac7a0de4f8d1d81959858908b6fe
https://pubmed.ncbi.nlm.nih.gov/20204745
https://pubmed.ncbi.nlm.nih.gov/20204745
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781607614999
Smooth muscle cells regulate the diameter of pulmonary arteries and the resistance to blood flow in the pulmonary circulation. These cells are normally relaxed to maintain low intrinsic vessel tone, but are contracted in pulmonary arterial hypertensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8a7389f65a601a3e5dcd4e5d49df44f
https://doi.org/10.1007/978-1-60761-500-2_26
https://doi.org/10.1007/978-1-60761-500-2_26
Autor:
Shreena Joshi, Alison M. Gurney
Publikováno v:
Signalling Pathways in Acute Oxygen Sensing: Novartis Foundation Symposium 272
Hypoxic pulmonary vasoconstriction (HPV) describes the vasoconstrictor response of pulmonary arteries to hypoxia, which directs blood flow towards better ventilated areas of the lung. Exactly how pulmonary arteries sense oxygen and mediate this respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3530fc8a73243bf6bd407f2623844f
https://doi.org/10.1002/9780470035009.ch17
https://doi.org/10.1002/9780470035009.ch17
Autor:
Alison M, Gurney, Shreena, Joshi
Publikováno v:
Novartis Foundation symposium. 272
Hypoxic pulmonary vasoconstriction (HPV) describes the vasoconstrictor response of pulmonary arteries to hypoxia, which directs blood flow towards better ventilated areas of the lung. Exactly how pulmonary arteries sense oxygen and mediate this respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b304752cd751ac42d922932f9c6cac2
https://pubmed.ncbi.nlm.nih.gov/16686438
https://pubmed.ncbi.nlm.nih.gov/16686438