Výsledky vyhledávání - "Shravani Kakarla"

Akademický článek

Direct differentiation of human pluripotent stem cells into vascular network along with supporting mural cells

Autor: Taylor Bertucci, Shravani Kakarla, Max A. Winkelman, Keith Lane, Katherine Stevens, Steven Lotz, Alexander Grath, Daylon James, Sally Temple, Guohao Dai

Publikováno v: APL Bioengineering, Vol 7, Iss 3, Pp 036107-036107-17 (2023)

During embryonic development, endothelial cells (ECs) undergo vasculogenesis to form a primitive plexus and assemble into networks comprised of mural cell-stabilized vessels with molecularly distinct artery and vein signatures. This organized vascula

Externí odkaz: https://doaj.org/article/298466156c8b467783a1161fb7d5c0cf

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Interstitial flow enhances the formation, connectivity, and function of 3D brain microvascular networks generated within a microfluidic device

Autor: Guohao Dai, Diana Y Kim, Nathaniel Silvia, Shravani Kakarla, Alexander Grath, Max A Winkelman

Publikováno v: Lab Chip

The convective transport of fluid through tissue is an important factor in human biology, including the development of brain microvascular networks (MVNs) with a functional blood-brain barrier (BBB). Engineering a functional 3D brain vascular network

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0694fb22fbd98c49c8955da1445d26a
https://pubmed.ncbi.nlm.nih.gov/34881385

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Differentiating Human Pluripotent Stem Cells to Vascular Endothelial Cells for Regenerative Medicine, Tissue Engineering, and Disease Modeling

Autor: Taylor B. Bertucci, Shravani Kakarla, Diana Kim, Guohao Dai

Publikováno v: Methods in Molecular Biology ISBN: 9781071617076

Vasculature plays a vital role in human biology as blood vessels transport nutrients and oxygen throughout the body. Endothelial cells (ECs), specifically, are key as they maintain barrier functions between the circulating blood and the surrounding t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ee92705b714b1ee63f47828030379e1
https://doi.org/10.1007/978-1-0716-1708-3_1