Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shravan Babu Girada"'
Autor:
Shilpak Bele, Shravan Babu Girada, Aramita Ray, Abhishek Gupta, Srinivas Oruganti, Phanithi Prakash Babu, Rahul SR Rayalla, Shashi Vardhan Kalivendi, Ahamed Ibrahim, Vishwajeet Puri, Venkateswar Adalla, Madhumohan R Katika, Richard DiMarchi, Prasenjit Mitra
Publikováno v:
eLife, Vol 9 (2020)
Given its glycemic efficacy and ability to reduce the body weight, glucagon-like peptide 1 receptor (GLP-1R) agonism has emerged as a preferred treatment for diabetes associated with obesity. We here report that a small-molecule Class 1 histone deace
Externí odkaz:
https://doaj.org/article/bc7951a1758043849dd74d907661bb2c
Autor:
Shravan Babu Girada, Ramya S. Kuna, Shilpak Bele, Zhimeng Zhu, N.R. Chakravarthi, Richard D. DiMarchi, Prasenjit Mitra
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1173-1185 (2017)
Objective: Upon activation, G protein coupled receptors (GPCRs) associate with heterotrimeric G proteins at the plasma membrane to initiate second messenger signaling. Subsequently, the activated receptor experiences desensitization, internalization,
Externí odkaz:
https://doaj.org/article/eca9030a2630473eac6dfff70f2f8824
Autor:
Richard D. DiMarchi, Rahul Sr Rayalla, Venkateswar Adalla, Vishwajeet Puri, Prasenjit Mitra, Shravan Babu Girada, Ahamed Ibrahim, Aramita Ray, Srinivas Oruganti, Abhishek Gupta, Phanithi Prakash Babu, Shashi Vardhan Kalivendi, Shilpak Bele, Madhumohan R. Katika
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Given its glycemic efficacy and ability to reduce the body weight, glucagon-like peptide 1 receptor (GLP-1R) agonism has emerged as a preferred treatment for diabetes associated with obesity. We here report that a small-molecule Class 1 histone deace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ada8ca07a981d7d9e0d0a6a953d3d52
https://doi.org/10.7554/elife.52212
https://doi.org/10.7554/elife.52212
Autor:
David Gonzalez, Jacob M. Wozniak, Ying Lin, Anand Patwardhan, Shravan Babu Girada, JoAnn Trejo, Thomas H. Smith, John D. Lapek, Neil Grimsey, Olivia Molinar-Inglis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 9
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Thrombin, a procoagulant protease, cleaves and activates protease-activated receptor-1 (PAR1) to promote inflammatory responses and endothelial dysfunction. In contrast, activated protein C (APC), an anticoagulant protease, activates PAR1 through a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea19d49efc22e33a4087cbfa3525dfdb
https://escholarship.org/uc/item/3mt8v038
https://escholarship.org/uc/item/3mt8v038
Autor:
Olivia Molinar-Inglis, JoAnn Trejo, Ying Lin, Jacob M. Wozniak, Shravan Babu Girada, Anand Patwardan, Neil Grimsey, John D. Lapek, David Gonzalez, Thomas W. Smith
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9768dbbbc7bb930cadfff983930658a2
https://doi.org/10.1096/fasebj.2020.34.s1.04784
https://doi.org/10.1096/fasebj.2020.34.s1.04784
Autor:
Zhimeng Zhu, Ramya S. Kuna, Prasenjit Mitra, Richard D. DiMarchi, Shravan Babu Girada, Shilpak Dilip Bele, N.R. Chakravarthi
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 10, Pp 1173-1185 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1173-1185 (2017)
Objective Upon activation, G protein coupled receptors (GPCRs) associate with heterotrimeric G proteins at the plasma membrane to initiate second messenger signaling. Subsequently, the activated receptor experiences desensitization, internalization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47c561ab427b8c813b998a2e1c04832
https://pubmed.ncbi.nlm.nih.gov/29031718
https://pubmed.ncbi.nlm.nih.gov/29031718
Autor:
Subbareddy Maddika, Ramya S. Kuna, Joyprashant Vallentyne, David L. Smiley, Shravan Babu Girada, Suman Asalla, Prasenjit Mitra, James Patterson, Richard D. DiMarchi
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 305:E161-E170
Glucagon-like peptide-1 receptor (GLP-1R) plays a major role in promoting glucose-stimulated insulin secretion in pancreatic β-cells. In the present study, we synthesized a novel functional analog of GLP-1 conjugated to tetramethyl rhodamine to moni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d358279603a1658515616bd6eb8c5c
https://doi.org/10.1152/ajpendo.00551.2012
https://doi.org/10.1152/ajpendo.00551.2012
Autor:
Anupama T. Row, Manika Pal Bhadra, Shasi V. Kalivendi, Debabrata Chowdhury, Swetha Pavani Rao, Partha P. Ghosh, Suman Asalla, Bhaskar Kandagatla, Prasenjit Mitra, Ramya S. Kuna, Utpal Bhadra, Ahamed Ibrahim, Srinivas Oruganti, Shravan Babu Girada
Publikováno v:
Scientific Reports
Dyslipidemia, particularly the elevated serum cholesterol levels, aggravate the pathophysiology of type 2 diabetes. In the present study we explored the relationship between fasting blood sugar and serum lipid parameters in human volunteers which rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2096cc694fa68d0a7c5639fd27877f3
https://doi.org/10.1038/srep27513
https://doi.org/10.1038/srep27513