Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Shravan, Madireddi"'
Autor:
Marcin Kowanetz, Thomas Powles, Hartmut Koeppen, Jane Grogan, Patrick Caplazi, Ira Mellman, Wei Zou, Sanjeev Mariathasan, Priti S. Hegde, Mark McCleland, Jacqueline McBride, Zora Modrusan, Romain Banchereau, Avantika S. Chitre, Alexis Scherl, Thomas D. Wu, Namrata S. Patil, Patricia de Almeida, Edward E. Kadel, III, Shravan Madireddi, Amelia Au-Yeung, Chikara Takahashi, Ying-Jiun Chen, Rhea Nersesian, Ehab A. El-Gabry, Mark D. Robida, Jeffrey C. Hung, Shadi Toghi Eshgi, W. Rodney Mathews, William E O'Gorman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background CD8+ tissue-resident memory T (TRM) cells, marked by CD103 (ITGAE) expression, are thought to actively suppress cancer progression, leading to the hypothesis that their presence in tumors may predict response to immunotherapy.Methods Here,
Externí odkaz:
https://doaj.org/article/ccc1e210948b41af9f921790f0cfde0d
Autor:
Haval Shirwan, Esma S. Yolcu, Kathryn J. MacLeod, Robert W. Miller, Zhenping Zhong, Hong Zhao, Shravan Madireddi, Kutlu G. Elpek, Abhishek K. Srivastava, Rich-Henry Schabowsky, Rajesh K. Sharma
Supplementary Figures 1-5, Methods from 4-1BB Ligand as an Effective Multifunctional Immunomodulator and Antigen Delivery Vehicle for the Development of Therapeutic Cancer Vaccines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d862589cdd94ed5132c29996098a81d
https://doi.org/10.1158/0008-5472.22381974.v1
https://doi.org/10.1158/0008-5472.22381974.v1
Autor:
Haval Shirwan, Esma S. Yolcu, Kathryn J. MacLeod, Robert W. Miller, Zhenping Zhong, Hong Zhao, Shravan Madireddi, Kutlu G. Elpek, Abhishek K. Srivastava, Rich-Henry Schabowsky, Rajesh K. Sharma
Therapeutic subunit vaccines based on tumor-associated antigens (TAA) represent an attractive approach for the treatment of cancer. However, poor immunogenicity of TAAs requires potent adjuvants for therapeutic efficacy. We recently proposed the tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e901b4db577ef7712b6cd2fb033b0f8
https://doi.org/10.1158/0008-5472.c.6500049.v1
https://doi.org/10.1158/0008-5472.c.6500049.v1
Autor:
Soyoung A. Oh, Kate Senger, Shravan Madireddi, Ilseyar Akhmetzyanova, Isabel E. Ishizuka, Somayeh Tarighat, Jerry H. Lo, David Shaw, Benjamin Haley, Sascha Rutz
Publikováno v:
Journal of Experimental Medicine. 219
Genome engineering of T lymphocytes, the main effectors of antitumor adaptive immune responses, has the potential to uncover unique insights into their functions and enable the development of next-generation adoptive T cell therapies. Viral gene deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9160930b3f6ed11d269afa4ab49e7d91
https://doi.org/10.1084/jem.20211530
https://doi.org/10.1084/jem.20211530
Autor:
Mahrukh A, Huseni, Lifen, Wang, Joanna E, Klementowicz, Kobe, Yuen, Beatrice, Breart, Christine, Orr, Li-Fen, Liu, Yijin, Li, Vinita, Gupta, Congfen, Li, Deepali, Rishipathak, Jing, Peng, Yasin, Şenbabaoǧlu, Zora, Modrusan, Shilpa, Keerthivasan, Shravan, Madireddi, Ying-Jiun, Chen, Eleanor J, Fraser, Ning, Leng, Habib, Hamidi, Hartmut, Koeppen, James, Ziai, Kenji, Hashimoto, Marcella, Fassò, Patrick, Williams, David F, McDermott, Jonathan E, Rosenberg, Thomas, Powles, Leisha A, Emens, Priti S, Hegde, Ira, Mellman, Shannon J, Turley, Mark S, Wilson, Sanjeev, Mariathasan, Luciana, Molinero, Mark, Merchant, Nathaniel R, West
Publikováno v:
Cell reports. Medicine.
Although immune checkpoint inhibitors (ICIs) are established as effective cancer therapies, overcoming therapeutic resistance remains a critical challenge. Here we identify interleukin 6 (IL-6) as a correlate of poor response to atezolizumab (anti-PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcbbc350b5cf438cceeb2d1bb3b0f44b
https://pubmed.ncbi.nlm.nih.gov/36599350
https://pubmed.ncbi.nlm.nih.gov/36599350
Autor:
Thomas Powles, Vinita Gupta, Zora Modrusan, Shravan Madireddi, Kobe C. Yuen, Romain Banchereau, Darren Tayama, Jane L. Grogan, Deepali Rishipathak, Patrick Williams, Edward E. Kadel, Sanjeev Mariathasan, Kenji Hashimoto, Jonathan E. Rosenberg, Shilpa Keerthivasan, Ying-Jiun Chen, Hartmut Koeppen, David F. McDermott, Congfen Li, Mahrukh Huseni, A. Thåström, X. Shen, Ning Leng, Li-Fen Liu, Michiel S. van der Heijden, Priti S. Hegde
Publikováno v:
Nature medicine, 26(5), 693-698. Nature Publishing Group
Nat Med
Nat Med
Although elevated plasma interleukin-8 (pIL-8) has been associated with poor outcome to immune checkpoint blockade 1, this has not been comprehensively evaluated in large randomized studies. Here we analyzed circulating pIL-8 and IL8 gene expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e57f9c6f06d90af2db552915b0ec30
https://doi.org/10.1038/s41591-020-0860-1
https://doi.org/10.1038/s41591-020-0860-1
Autor:
Mahrukh A. Huseni, Lifen Wang, Joanna E. Klementowicz, Kobe Yuen, Beatrice Breart, Christine Orr, Li-fen Liu, Yijin Li, Vinita Gupta, Congfen Li, Deepali Rishipathak, Jing Peng, Yasin Şenbabaoǧlu, Zora Modrusan, Shilpa Keerthivasan, Shravan Madireddi, Ying-Jiun Chen, Eleanor J. Fraser, Ning Leng, Habib Hamidi, Hartmut Koeppen, James Ziai, Kenji Hashimoto, Marcella Fassò, Patrick Williams, David F. McDermott, Jonathan E. Rosenberg, Thomas Powles, Leisha A. Emens, Priti S. Hegde, Ira Mellman, Shannon J. Turley, Mark S. Wilson, Sanjeev Mariathasan, Luciana Molinero, Mark Merchant, Nathaniel R. West
Publikováno v:
Cell Reports Medicine. 4:100878
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0d80979e302b8951f90b2e33323465f
https://doi.org/10.1016/j.xcrm.2022.100878
https://doi.org/10.1016/j.xcrm.2022.100878
Autor:
Yanli Yang, Sherry H. Yeh, Shravan Madireddi, Wadim L. Matochko, Chen Gu, Patricia Pacheco Sanchez, Mark Ultsch, Gladys De Leon Boenig, Seth F. Harris, Brandon Leonard, Suzie J. Scales, Jing W. Zhu, Erin Christensen, Julie Q. Hang, Randall J. Brezski, Scot Marsters, Avi Ashkenazi, Siddharth Sukumaran, Henry Chiu, Rafael Cubas, Jeong M. Kim, Greg A. Lazar
Publikováno v:
mAbs
Agonism of members of the tumor necrosis factor receptor superfamily (TNFRSF) with monoclonal antibodies is of high therapeutic interest due to their role in immune regulation and cell proliferation. A major hurdle for pharmacologic activation of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5a54c9991525ce536360d89bf35e3c
http://europepmc.org/articles/PMC6748612
http://europepmc.org/articles/PMC6748612
Autor:
W. Rodney Mathews, Ying-Jiun Chen, Marcin Kowanetz, Jane L. Grogan, Chikara Takahashi, Mark McCleland, Ira Mellman, Thomas Powles, Jacqueline McBride, Mark D. Robida, Avantika S. Chitre, William E. O'Gorman, Shravan Madireddi, Hartmut Koeppen, Edward E. Kadel, Zora Modrusan, Patrick Caplazi, Thomas D. Wu, Shadi Toghi Eshgi, Alexis Scherl, Rhea Nersesian, Ehab Elgabry, Amelia Au-Yeung, Jeffrey Hung, Namrata Patil, Wei Zou, Priti Hegde, Patrícia de Almeida, Sanjeev Mariathasan, Romain Banchereau
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundCD8+ tissue-resident memory T (TRM) cells, marked by CD103 (ITGAE) expression, are thought to actively suppress cancer progression, leading to the hypothesis that their presence in tumors may predict response to immunotherapy.MethodsHere, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973117f29bc29683e2495f0620864a71
https://jitc.bmj.com/content/9/4/e002231.full
https://jitc.bmj.com/content/9/4/e002231.full
Autor:
Julie Hunkapiller, Maciej Migdal, Sanjeev Mariathasan, Matthew L. Albert, Edward E. Kadel, Diana Chang, Suresh Selvaraj, Suchit Jhunjhunwala, Jieming Chen, Deepti R. Nagarkar, Jason A. Vander Heiden, Kiran Mukhyala, Matthew J. Brauer, Shravan Madireddi, Christian Hammer
Publikováno v:
Briefings in Bioinformatics
Immunogenetic variation in humans is important in research, clinical diagnosis and increasingly a target for therapeutic intervention. Two highly polymorphic loci play critical roles, namely the human leukocyte antigen (HLA) system, which is the huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da1499b3d9934090bab7d49bd0a6cd7
https://doi.org/10.1101/2020.04.24.060459
https://doi.org/10.1101/2020.04.24.060459