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of 8
pro vyhledávání: '"Shraddheya Kumar Patel"'
Autor:
Satya Ranjan Sahu, Abinash Dutta, Doureradjou Peroumal, Premlata Kumari, Bhabasha Gyanadeep Utakalaja, Shraddheya Kumar Patel, Narottam Acharya
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1254-1283 (2024)
Abstract Disseminated fungal infections account for ~1.5 million deaths per year worldwide, and mortality may increase further due to a rise in the number of immunocompromised individuals and drug-resistance fungal species. Since an approved antifung
Externí odkaz:
https://doaj.org/article/b93bc1c0f9664b2b9dc23a43d020d6e8
Autor:
Shraddheya Kumar Patel, Satya Ranjan Sahu, Bhabasha Gyanadeep Utkalaja, Swagata Bose, Narottam Acharya
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTCandida albicans is a pathobiont that inflicts serious bloodstream fungal infections in individuals with compromised immunity and gut dysbiosis. Genomic diversity in the form of copy number alteration, ploidy variation, and loss of heterozygo
Externí odkaz:
https://doaj.org/article/4096e3b998dd4ba995d0f0ba7a9d723f
Autor:
Satya Ranjan Sahu, Swagata Bose, Manish Singh, Premlata Kumari, Abinash Dutta, Bhabasha Gyanadeep Utkalaja, Shraddheya Kumar Patel, Narottam Acharya
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Candidiasis is a mycosis caused by opportunistic Candida species. The occurrence of fungal infections has considerably increased in the last few years primarily due to an increase in the number of immune-suppressed individuals. Alarming bloodstream i
Externí odkaz:
https://doaj.org/article/3238cda19b4d4db5aeb3da941c744618
Autor:
Kodavati Manohar, Dileep Vasudevan, Rajivgandhi Sundaram, Narottam Acharya, Shraddheya Kumar Patel
Publikováno v:
FEBS Letters. 595:1328-1349
An assembly of multiprotein complexes achieves chromosomal DNA replication at the replication fork. In eukaryotes, proliferating cell nuclear antigen (PCNA) plays a vital role in the assembly of multiprotein complexes at the replication fork and is e
Autor:
Kodavati, Manohar, Prashant, Khandagale, Shraddheya Kumar, Patel, Jugal Kishor, Sahu, Narottam, Acharya
Publikováno v:
The Journal of Biological Chemistry
DNA polymerase eta (Polη) is a unique translesion DNA synthesis (TLS) enzyme required for the error-free bypass of ultraviolet ray (UV)-induced cyclobutane pyrimidine dimers in DNA. Therefore, its deficiency confers cellular sensitivity to UV radiat
Publikováno v:
Biochemical Society transactions. 48(6)
Interaction of PCNA with DNA polymerase is vital to efficient and processive DNA synthesis. PCNA being a homotrimeric ring possesses three hydrophobic pockets mostly involved in an interaction with its binding partners. PCNA interacting proteins cont
Autor:
Narottam Acharya, Prashant Khandagale, Satya Ranjan Sahu, Kodavati Manohar, Shraddheya Kumar Patel, Doureradjou Peroumal, Premlata Kumari
Publikováno v:
Current genetics. 65(3)
DNA polymerases are evolved to extend the 3′-OH of a growing primer annealed to a template DNA substrate. Since replicative DNA polymerases have a limited role while replicating structurally distorted template, translesion DNA polymerases mostly fr
Autor:
Premlata Kumari, Doureradjou Peroumal, Kodavati Manohar, Narottam Acharya, Shraddheya Kumar Patel, Satya Ranjan Sahu
Publikováno v:
Cellular microbiologyREFERENCES. 21(12)
Deletion of DNA polymerase eta (Rad30/Polη) in pathogenic yeast Candida albicans is known to reduce filamentation induced by serum, ultraviolet, and cisplatin. Because nonfilamentous C. albicans is widely accepted as avirulent form, here we explored