Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shraddha S, Rane"'
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 548 (2024)
Psoriasis is a lifelong, systemic, immune mediated inflammatory skin condition, affecting 1–3% of the world’s population, with an impact on quality of life similar to diseases like cancer or diabetes. Genetics are the single largest risk factor i
Externí odkaz:
https://doaj.org/article/33d477433b9b43ca93d617a4da90ccdf
Publikováno v:
Journal of Immunotoxicology, Vol 19, Iss 1, Pp 1-7 (2022)
Biotherapeutic monoclonal antibodies (mAb) play important roles in clinical medicine but their potential to elicit immune responses in patients remains a major issue. In a study designed to investigate the effect of aggregation on immunogenic respons
Externí odkaz:
https://doaj.org/article/16b939625b724fcaace297b900668148
Autor:
Rebecca J. Dearman, Shahid Uddin, Adrian Podmore, Stephen Bishop, Maryam Shah, Jeremy P. Derrick, Ian Kimber, Shraddha S. Rane, Alain Pluen
Publikováno v:
Rane, S, Dearman, R, Kimber, I, Uddin, S, Bishop, S, Shah, M, Podmore, A, Pluen, A & Derrick, J 2019, ' Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies ', Pharmaceutical Research, vol. 36, no. 4, 51 . https://doi.org/10.1007/s11095-019-2586-7
Pharmaceutical Research
Pharmaceutical Research
Purpose Anti-drug antibodies can impair the efficacy of therapeutic proteins and, in some circumstances, induce adverse health effects. Immunogenicity can be promoted by aggregation; here we examined the ability of recombinant mouse heat shock protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a230ed03e5ebb514aaf478cca821d3
https://doi.org/10.1007/s11095-019-2586-7
https://doi.org/10.1007/s11095-019-2586-7
Autor:
Robert C. Rees, Morgan G. Mathieu, Rachael L. Metheringham, Danielle McDonald, Murrium Ahmad, Shraddha S. Rane, Jaimy Saif, Lindy G. Durrant, A. Graham Pockley, Jayakumar Vadakekolathu, Stephanie E. B. McArdle
Publikováno v:
European Journal of Immunology. 44:994-1004
Treatment options for patients with advanced prostate cancer remain limited and rarely curative. Prostatic acid phosphatase (PAP) is a prostate-specific protein overexpressed in 95% of prostate tumours. An FDA-approved vaccine for the treatment of ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1591aa6423fb051307e3e3432f40d75b
https://doi.org/10.1002/eji.201343863
https://doi.org/10.1002/eji.201343863
Publikováno v:
Cancer Immunology ISBN: 9783662449455
The aim of the immunotherapy and peptide therapeutics is to destroy cancer cells without eliciting lethal side effects and sustain the long-lasting immune memory. Targeting major histocompatibility complex (MHC) class I and class II epitopes and mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::379e23a9c1f7810ded16fb2f3ec41cd4
https://doi.org/10.1007/978-3-662-44946-2_4
https://doi.org/10.1007/978-3-662-44946-2_4
Autor:
Jaimy M S, Saif, Jayakumar, Vadakekolathu, Shraddha S, Rane, Danielle, McDonald, Murrium, Ahmad, Morgan, Mathieu, A Graham, Pockley, Lindy, Durrant, Rachael, Metheringham, Robert C, Rees, Stephanie E B, McArdle
Publikováno v:
European journal of immunology. 44(4)
Treatment options for patients with advanced prostate cancer remain limited and rarely curative. Prostatic acid phosphatase (PAP) is a prostate-specific protein overexpressed in 95% of prostate tumours. An FDA-approved vaccine for the treatment of ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0bd21f227a6086cef8d1bae5c7f154e8
https://pubmed.ncbi.nlm.nih.gov/24338683
https://pubmed.ncbi.nlm.nih.gov/24338683
Autor:
Rane S; School of Health Sciences, Purdue University, West Lafayette, IN, USA., Harris J; School of Health Sciences, Purdue University, West Lafayette, IN, USA.
Publikováno v:
Risk analysis : an official publication of the Society for Risk Analysis [Risk Anal] 2021 Aug; Vol. 41 (8), pp. 1257-1273. Date of Electronic Publication: 2020 Nov 17.
Autor:
Fernandes L; Department of Pulmonary Medicine, Goa Medical College, Goa, India., Rane S; Department of Pulmonary Medicine, Goa Medical College, Goa, India., Mandrekar S; Department of Pathology, Goa Medical College, Goa, India., Mesquita AM; Department of Pulmonary Medicine, Goa Medical College, Goa, India.
Publikováno v:
Journal of health & pollution [J Health Pollut] 2019 Nov 27; Vol. 9 (24), pp. 191209. Date of Electronic Publication: 2019 Nov 27 (Print Publication: 2019).
Autor:
Rane S; 1School of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907., Harris JT, Foss EK, Sheffield C; School of Health Sciences, Purdue University, 550 Stadium Mall Drive, West Lafayette, IN 47907.
Publikováno v:
Health physics [Health Phys] 2018 Nov; Vol. 115 (5), pp. 637-645.