Výsledky vyhledávání - "Shraddha Kamdar"

Akademický článek

Activation of Lymphocytes in Healthy Neonates Within Hours of Birth

Autor: Gaayathri Ariyakumar, Sarah Gee, Abhishek Das, Shraddha Kamdar, Rachel M. Tribe, Deena L. Gibbons

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

It is now established that immune maturation occurs along a defined trajectory in the weeks and months after birth, but the immediate changes that occur within immune cells following birth is less clear. In this study, we monitored the immune profile

Externí odkaz: https://doaj.org/article/ebc822e6be6540438cc5ce0064f29f2b

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Rapid immune perturbations during sepsis and necrotising enterocolitis in preterm babies

Autor: Abhishek Das, Gaayathri Ariyakumar, Shraddha Kamdar, Adele Barugahare, Deanna Deveson, Sarah Gee, Kate Costeloe, Martin Davey, Paul Fleming, Deena Gibbons

Deaths complicated by infection are a major cause of mortality in preterm babies. Here we study the influence of bacterial sepsis and the gut inflammatory disorder necrotising enterocolitis (NEC), frequently associated with bacterial complications, o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f1531610c1252e033bb83ec7a722ca7
https://doi.org/10.21203/rs.3.rs-2017208/v1

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Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study

Publikováno v: Lancet oncology
22 (2021): 765–778. doi:10.1016/S1470-2045(21)00213-8
info:cnr-pdr/source/autori:Monin, Leticia; Laing, Adam G.; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; del Molino del Barrio, Irene; Alaguthurai, Thanussuyah; Domingo-Vila, Clara; Hayday, Thomas S.; Graham, Carl; Seow, Jeffrey; Abdul-Jawad, Sultan; Kamdar, Shraddha; Harvey-Jones, Elizabeth; Graham, Rosalind; Cooper, Jack; Khan, Muhammad; Vidler, Jennifer; Kakkassery, Helen; Sinha, Shubhankar; Davis, Richard; Dupont, Liane; Francos Quijorna, Isaac; O'Brien-Gore, Charlotte; Lee, Puay Ling; Eum, Josephine; Conde Poole, Maria; Joseph, Magdalene; Davies, Daniel; Wu, Yin; Swampillai, Angela; North, Bernard V.; Montes, Ana; Harries, Mark; Rigg, Anne; Spicer, James; Malim, Michael H.; Fields, Paul; Patten, Piers; Di Rosa, Francesca; Papa, Sophie; Tree, Timothy; Doores, Katie J.; Hayday, Adrian C.; Irshad, Sheeba/titolo:Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study/doi:10.1016%2FS1470-2045(21)00213-8/rivista:Lancet oncology (Print)/anno:2021/pagina_da:765/pagina_a:778/intervallo_pagine:765–778/volume:22
The Lancet. Oncology

Summary Background The efficacy and safety profiles of vaccines against SARS-CoV-2 in patients with cancer is unknown. We aimed to assess the safety and immunogenicity of the BNT162b2 (Pfizer–BioNTech) vaccine in patients with cancer. Methods For t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd7e59dcd46956cf15585304c1e9092d
https://doi.org/10.1016/s1470-2045(21)00213-8

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Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 119(34)

Whereas pathogen-specific T and B cells are a primary focus of interest during infectious disease, we have used COVID-19 to ask whether their emergence comes at a cost of broader B cell and T cell repertoire disruption. We applied a genomic DNA-based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d30cd379a7c09962953e558243f5a1
https://pubmed.ncbi.nlm.nih.gov/35943978

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Activation of the neonatal immune system in healthy neonates within hours of birth

Autor: Gaayathri Ariyakumar, Sarah Gee, Abhishek Das, Shraddha Kamdar, Rachel M Tribe, Deena L Gibbons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acf7bbb22e7dc5f37e1ac72fcaf89b2e
https://doi.org/10.1101/2022.02.25.481959

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Interim results of the safety and immune-efficacy of 1 versus 2 doses of COVID-19 vaccine BNT162b2 for cancer patients in the context of the UK vaccine priority guidelines

BackgroundThe efficacy and safety profile of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been definitively established in immunocompromised patient populations. Patients with a known cancer diagnosis were hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f306c775f6a44fc6cb777201f33ee31d
https://doi.org/10.1101/2021.03.17.21253131

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Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients

Autor: Sheeba Irshad, Paul Fields, Doraid Alrifai, Richard Davis, Yin Wu, Isaac Francos Quijorna, Anna Lorenc, Eva Bugallo-Blanco, Julie Nuo En Chan, Anne Rigg, Jennifer Vidler, Adrian Hayday, Aadil A. Khan, Julien de Naurois, Charlotte Moss, Sultan Abdul-Jawad, Pierre Vantourout, Louisa Mcdonald, Duncan R. McKenzie, Mieke Van Hemelrijck, Paul R. Barber, Irene del Molino del Barrio, Sophie Papa, Katharine Bailey, Deborah Enting, Beth Russell, Sophie Hazell, Sarah Gee, Tony Ng, Sarah Ryan, You Zhou, Anthony C. C. Coolen, Iva Zlatareva, Piers E.M. Patten, Adam Laing, Sophia N. Karagiannis, Miguel Muñoz-Ruiz, Luca Bau, Thomas Hayday, Yadanar Lwin, Shraddha Kamdar, Matthew Fish, Reuben Benjamin, Rozalyn Yorke, Aislinn Jennings, Katie J. Doores, Mayur Kumar, Thanussuyah Alaguthurai, Leticia Monin, Mark Rowley, James Spicer

Publikováno v: Cancer Cell

Given the immune system's importance for cancer surveillance and treatment, we have investigated how it may be affected by SARS-CoV-2 infection of cancer patients. Across some heterogeneity in tumor type, stage, and treatment, virus-exposed solid can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274ba1e471a9e1eb7ce3ea8ab6a93c1a

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Perinatal inflammation influences but does not arrest rapid immune development in preterm babies

Autor: Deena L. Gibbons, William G. Wade, Kate Costeloe, Adam Laing, Paul Fleming, Michael Millar, Richard Hutchinson, Katherine Ansbro, Shraddha Kamdar, Fiona Stacey

Publikováno v: Kamdar, S, Hutchinson, R, Laing, A, Stacey, F, Ansbro, K, Millar, M R, Costeloe, K, Wade, W G, Fleming, P & Gibbons, D L 2020, ' Perinatal Inflammation Influences but Does Not Arrest Rapid Immune Development in Preterm Babies ', Nature Communications, vol. 11, no. 1, 1284, pp. 1-14 . https://doi.org/10.1038/s41467-020-14923-8
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications

Infection and infection-related complications are important causes of death and morbidity following preterm birth. Despite this risk, there is limited understanding of the development of the immune system in those born prematurely, and of how this de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb6b5374e1813e9d79a8413e086923c
https://doi.org/10.1038/s41467-020-14923-8

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A dynamic COVID-19 immune signature includes associations with poor prognosis

Autor: Aislinn Jennings, Isaac Francos-Quijorna, Manu Shankar-Hari, Adrian Hayday, Duncan R. McKenzie, John Cason, Thomas Hayday, Shraddha Kamdar, Yin Wu, Richard Davis, Matthew Fish, Kate Brooks, Blair Merrick, Katie J. Doores, Eva Bugallo-Blanco, Adam Laing, Kai Kisand, Jeremy Mason, Iva Zlatareva, Kola Babalola, Magdalene Joseph, Francesca Di Rosa, Jeffrey Seow, Philippe Moingeon, Anna Lorenc, Pärt Peterson, Daniel Davies, Mohammad A. A. Ibrahim, Efstathios Theodoridis, Federico Lopez Gomez, Liis Haljasmägi, Pierre Vantourout, Vasiliki Sofra, Abhishek Das, Maria Greco, Christine Mant, Sarah Gee, Julie Nuo En Chan, Carl Graham, Leticia Monin, Loubna Chadli, Irene del Molino del Barrio, Miguel Muñoz-Ruiz, Florencia Cano, Karen Bisnauthsing, Lauren Martinez, Sultan Abdul-Jawad, Sarah Ryan, Jonathan D. Edgeworth, Joshua D. Freedman

Publikováno v: Nature medicine
26 (2020): 1623–1635. doi:10.1038/s41591-020-1038-6
info:cnr-pdr/source/autori:Laing, Adam G.; Lorenc, Anna; del Molino del Barrio, Irene; Das, Abhishek; Fish, Matthew; Monin, Leticia; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; Hayday, Thomas S.; Francos-Quijorna, Isaac; Kamdar, Shraddha; Joseph, Magdalene; Davies, Daniel; Davis, Richard; Jennings, Aislinn; Zlatareva, Iva; Vantourout, Pierre; Wu, Yin; Sofra, Vasiliki; Cano, Florencia; Greco, Maria; Theodoridis, Efstathios; Freedman, Joshua; Gee, Sarah; Chan, Julie Nuo En; Ryan, Sarah; Bugallo-Blanco, Eva; Peterson, Pärt; Kisand, Kai; Haljasmägi, Liis; Chadli, Loubna; Moingeon, Philippe; Martinez, Lauren; Merrick, Blair; Bisnauthsing, Karen; Brooks, Kate; Ibrahim, Mohammad A.A.; Mason, Jeremy; Lopez Gomez, Federico; Babalola, Kola; Abdul-Jawad, Sultan; Cason, John; Mant, Christine; Seow, Jeffrey; Graham, Carl; Doores, Katie J.; Di Rosa, Francesca; Edgeworth, Jonathan; Shankar-Hari, Manu; Hayday, Adrian C./titolo:A dynamic COVID-19 immune signature includes associations with poor prognosis/doi:10.1038%2Fs41591-020-1038-6/rivista:Nature medicine (Print)/anno:2020/pagina_da:1623/pagina_a:1635/intervallo_pagine:1623–1635/volume:26
Nature Medicine

Improved understanding and management of COVID-19, a potentially life-threatening disease, could greatly reduce the threat posed by its etiologic agent, SARS-CoV-2. Toward this end, we have identified a core peripheral blood immune signature across 6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f5fa781e4a5acfc0a8216290f81914
http://www.cnr.it/prodotto/i/439414

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