Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Shraddha Bhutkar"'
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Akademický článek
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3
Repurposing an Antiepileptic Drug for the Treatment of Glioblastoma
Autor: Anjali Yadav, Ali Alnakhli, Hari Priya Vemana, Shraddha Bhutkar, Aaron Muth, Vikas V. Dukhande
Publikováno v: Pharm Res
PURPOSE: Glioblastoma multiforme (GBM) is a grade IV, highly proliferative, and malignant form of brain tumor with a 5-year survival rate at ~ 5%. Current treatment strategies for GBM include surgery, radiation, and chemotherapy. Major challenges in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf335f6be8af1976b7cb3624da17f20
https://doi.org/10.1007/s11095-022-03399-4
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6
Akademický článek
Liver Biopsy Hydroxyproline Content Is a Diagnostic for Hepatocellular Carcinoma in Murine Models of Nonalcoholic Steatohepatitis
Autor: Tyler L. Bissoondial, Yiguang Han, Stephanie Mullan, Amrit K. Pabla, Kiera Spahn, Steven Shi, Lana Zheng, Ping Zhou, Kai Jiang, Natalia Prakash, Shraddha Bhutkar, Quaisar Ali, Jingsong Li, Zhijian Hu, Anthony J. Pellicano, Itzhak D. Goldberg, Prakash Narayan
Publikováno v: Diagnostics, Vol 10, Iss 10, p 784 (2020)
There is increasing evidence that nonalcoholic steatohepatitis (NASH) is a risk factor for hepatocellular carcinoma (HCC) in the absence of cirrhosis, a phenomenon termed noncirrhotic HCC. Early diagnosis of HCC is critical to a favorable prognosis.
Externí odkaz: https://doaj.org/article/135af65593844de493e4173d5d75c0ff
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7
Metabolic Alterations and Mitochondrial Dysfunction Underlie Hepatocellular Carcinoma Cell Death Induced by a Glycogen Metabolic Inhibitor
Autor: Shrikant Barot, Olivia J. Stephenson, Hari Priya Vemana, Anjali Yadav, Shraddha Bhutkar, Louis D. Trombetta, Vikas V. Dukhande
Publikováno v: Biochem Pharmacol
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths. There is an urgent need for new targets to treat HCC due to limited treatment options and drug resistance. Many cancer cells are known to have high amount of glycog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107e75cc3e1aa4cb719e5466623c8402
https://europepmc.org/articles/PMC10039449/
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8
A novel gene therapy for neurodegenerative Lafora disease via EPM2A-loaded DLinDMA lipoplexes
Autor: Vikas V. Dukhande, Aishwarya Saraswat, Shraddha Bhutkar, Ketan Patel, Hari Priya Vemana
Publikováno v: Nanomedicine. 16:1081-1095
Aim: To develop novel cationic liposomes as a nonviral gene delivery vector for the treatment of rare diseases, such as Lafora disease – a neurodegenerative epilepsy. Materials & methods: DLinDMA and DOTAP liposomes were formulated and characterize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35cd6a19ed246a064a9b1bd59151c9b3
https://doi.org/10.2217/nnm-2020-0477
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10
A novel gene therapy for neurodegenerative Lafora disease via
Autor: Hari Priya, Vemana, Aishwarya, Saraswat, Shraddha, Bhutkar, Ketan, Patel, Vikas V, Dukhande
Publikováno v: Nanomedicine (Lond)
AIM: To develop novel cationic liposomes as a nonviral gene delivery vector for the treatment of rare diseases, such as Lafora disease – a neurodegenerative epilepsy. MATERIALS & METHODS: DLinDMA and DOTAP liposomes were formulated and characterize
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::80fe4ed32a32b577f5c573519301d7c5
https://pubmed.ncbi.nlm.nih.gov/33960213
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